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1
Using
Animal Models in Biomedical Research: A Primer for the ...
Using this formula, Table 3.9.1 highlights the sample size required Rodent
Sentinel Programme 131 Selection of Sentinel Animal Age and Sex of Sentinel
Number of Sentinels and Identification.
Pierce K. H. Chow, Robert T. H. Ng, Bryan E. Ogden, 2008
2
Environmental Toxicology and Risk Assessment: Biomarkers and ...
The classic example of the use of a sentinel animal model entailed the use of
canaries in underground mines as early warning systems for changes in air
quality, generally due to the accumulation of the odorless carbon monoxide2.
David A. Bengtson, Diane S. Henshel, 1996
3
The Mouse in Biomedical Research: Normative Biology, ...
Care must be taken that the sentinel animal is clearly identified. If males are
present, fighting may occur due to the introduction of a new animal. Some
facilities utilize ovariectomized females to avoid the possibility of pregnancy and
birth by the ...
4
Animal Disease Surveillance and Survey Systems: Methods and ...
G It of a sentinel animal's response to the infectious agent of interest is hed
through clinical examination, serological testing, or identifica2 infectious agent
itself. Using clinical examinations as the sole detera positive sentinel animal is
tenuous.
5
Animals as Sentinels of Environmental Health Hazards
Those circumstances include the following: • Accumulated chemicals—cases in
which the agent under investigation is persistent and stored in animal tissues, so
a sentinel animal could serve as a sampling and averaging device. • Complex ...
Committee on Animals as Monitors of Environmental Hazards, Board on Environmental Studies and Toxicology, Commission on Life Sciences, 1991
6
Clinical Laboratory
Animal Medicine: An Introduction
Transferring soiled bedding material to sentinel animal cages is usually effective.
Airborne spread of infection is less reliable and impeded when microisolator or
ventilated caging systems are used. The increased use of individually ventilated
...
Karen Hrapkiewicz, Leticia Medina, 2013
7
The Importance of laboratory
animal genetics Health, and the ...
I think something we've sort of stumbled on accidentally was to start serially
bleeding the same sentinel animal so that we'd have an easy way to tell if we had
a false positive without waiting a long period of time; so we sequentially bleed the
...
Edward C. Jr. Melby, 1984
8
Infectious Disease Surveillance
Sentinel animal surveillance Active monitoring of animals for zoonotic pathogens
can provide early recognition of human health risks and may allow for control
efforts prior to the transmission of disease to humans. Serologic testing is often ...
Nkuchia M. M'ikanatha, Ruth Lynfield, Chris A. Van Beneden, 2013
9
Ecotoxicity and Human Health: A Biological Approach to ...
ANIMAL SENTINELS When exposed to environmental levels of contamination, a
"sentinel" animal exhibits measureable biological changes that can be used to
evaluate the degree of contamination and provide an early warning of its
potential ...
Arthur D. Bloom, Frederick de Serres, 1995
10
Technical Report on Toxicology and Carcinogenesis Studies of ...
The Sentinel Animal Program is part of the periodic monitoring of animal health
that occurs during the toxicologic evaluation of chemical compounds. Under this
program, the disease state of the rodents is monitored via serology on sera from ...
