KSIĄŻKI POWIĄZANE ZE SŁOWEM «SOFT DRUG»
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1
Sequencing and Prediction of Adolescent
Soft Drug ...
The systematic review cross-validation involved comparing the quantitative findings for two major hypotheses to those yielded from 36 primary studies examined in the systematic review.
2
An Introduction to
Drug Design
Definition and claimed advantages: (i) Soft Drug: The term 'Soft Drug' is taken
from the concept of Hard and Soft acids and bases. Thus a hard drug means a
compound which is hard to metabolise and is non-metabolisable, whereas a soft
...
S. N. Pandeya, J. R. Dimmock, 1997
3
Dermal Absorption and Toxicity Assessment, Second Edition
Michael S. Roberts. Prodrug Soft drug + Pro-soft drug P Pharmacologically
inactive Site of pharmacological action Site of metabolism + Pharmacologically
inactive (A) Parent drug Promoeity Detoxification Detoxification P Elim. P P P +P
Elim.
4
Drug Metabolism: Current Concepts
A soft drug is a pharmacologically active compound that is deactivated in a
predictable and controllable way after it has fulfilled its therapeutic role [14]. A soft
drug, therefore, not only possesses the required pharmacological activity, but
also ...
Corina Ionescu, Mino R. Caira, 2006
5
Pharmacology: Principles and Practice
Uncontrolled duration Potential toxicity Shorten duration via metabolism/
elimination Scheme 19.13 Contrasting dispositions of a drug, prodrug, and soft
drug. (A) depicts a generalized version of a standard drug's pattern of observed
activities.
Miles Hacker, William S. Messer II, Kenneth A. Bachmann, 2009
6
Current Medicinal Chemistry
In vivo metabolic pathways for an ideal soft drug. Bodor and coworkers have
proposed the concept of soft drugs to minimize the problems associated with
hard drugs in eliciting selective local action [2-6]. Soft drugs are "
pharmacologically ...
7
Drug Misusing Offenders and the Criminal Justice System: The ...
Two countries - the United States and Northern Ireland - differ remarkably in this
respect, with rates of more than 40 percent of all soft drug users who ever
consume hard drugs. This may be due to the more trivial nature of some popular "
hard" ...
8
Ocular Theraputics and
Drug Delivery
One aspect of Bodor' s work has been used to successfully design novel drugs
for the eye using a soft drug approach. This design process starts with either a
known inactive metabolite or a close analog. The metabolite is then chemically ...
9
New Drugs for Asthma, Allergy and COPD
Pharmacological and Chemical Aims for Soft-Drug Development A soft drug is
active by itself, has therapeutic efficacy at the site of application, and is rapidly
and predictably inactivated during its systemic uptake and distribution [10]. A soft
ICS ...
Trevor T. Hansel, Peter J. Barnes, 2001
10
Prodrugs and Targeted Delivery: Towards Better ADME Properties
The term “soft drug” (sometimes called “antedrug”) was first introduced by Bodor [
1] about 30 years ago to contrast Ariens' drug design concept of nonmetabolized
“hard drugs,” the latter intending to avoid problems caused by reactive species ...
WIADOMOŚCI, KTÓRE ZAWIERAJĄ SŁOWO «SOFT DRUG»
Sprawdź, o czym dyskutuje się w prasie krajowej i zagranicznej oraz jak jest stosowane słowo
soft drug w wiadomościach.
Police commissioner's cannabis U-turn after suggesting people …
“It does send a message that drugs are OK - there can be no doubt that there a significant amount of people ... Do we stop looking at burglaries, soft drug use? «Mirror.co.uk, Lip 15»
Techno guru: "Legalise soft drugs"
Peter Decuypere, the founder of the I Love Techno rave, has written an open letter in which he calls for the legalisation of soft drugs. Mr Decuypere intervenes in ... «Expatica Belguim, Lip 15»
'You will not be arrested for using drugs': What a sane drug policy …
Dutch law distinguishes between "soft drugs," like marijuana, and "hard" ones, like cocaine and heroin. Possession and use of up to 5 grams of marijuana, and 1 ... «Washington Post, Gru 14»
'Marijuana is no soft drug'
"DON'T believe anyone who tells you marijuana is a soft drug." This was the advice Judge Michael Rackemann gave to Joshua Matthew Gillham as he stood in ... «Mackay Daily Mercury, Sie 14»
Fight organized crime by legalizing soft drugs
Does caffeine lead to cocaine use? Obviously not. But if caffeine were outlawed, a black market would emerge. Drug gangs, which are highly skilled at operating ... «National Post, Lip 14»
Classifying between hard and soft drugs should be shunned …
Those caught in possession of cannabis – perceived by many as being a “soft” drug – would instead be exempted from appearing before the social board, ... «MaltaToday, Lip 14»
Pope for Legal Dope? Still Nope.
In 2001, the Vatican's Pontifical Council for Health Care urged governments to resist legalization even on soft drugs in the manual “Church, Drugs, and Drug ... «TIME, Cze 14»
NZ's world-high drug use no surprise - Experts
The use of drugs like methamphetamine and ecstasy was also the highest in the world, ... "We've treated cannabis as a soft drug and we've ignored the risk of ... «New Zealand Herald, Sty 12»
Dutch fear threat to liberalism in "soft drugs" curbs
The push to clamp down on soft drugs has come mainly from the Christian Democrats, the junior partner in the minority government and one of the larger parties ... «Reuters, Paz 11»
Celebrities write to David Cameron urging decriminalisation of drug …
If you decriminalise soft drugs but not hard drugs, all the profits for the drug barons will be in the hard drugs and those drugs will therefore be pushed to an even ... «Mirror.co.uk, Cze 11»
