KSIĄŻKI POWIĄZANE ZE SŁOWEM «SYNGENEIC»
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1
Effective Combination of
Syngeneic HCT with CRCL Vaccination ...
CD4+CD25+ regulatory T cells (Treg) play a central role in the prevention of autoimmunity and in the control of immune responses by down-regulating the function of effector CD4+ or CD8+ T cells.
2
Haematological Oncology
syngeneic GVHD results in just an acute form of syngeneic GVHD in the
recipients, that resolves within 2 weeks. The addition of CD4+ T-cells from the
animals with syngeneic GVHD both augmented the transfer of the acute form of
syngeneic ...
Armand Keating, Adrian Newland, James O. Armitage, 1992
3
Graft-vs.-Host Disease, Second Edition,
after syngeneic BMT and CsA therapy and after allogeneic BMT are
indistinguishable histologically, this single observation also reverses a landmark
concept that histocompatibility differences are absolute requirements for the
induction of ...
James Ferrara, Kenneth R. Cooke, H. Joachim Deeg, 1996
4
Thomas' Hematopoietic Cell Transplantation
The preclinical literature contains conflicting reports regarding the efficacy of
syngeneic HCT in curing autoimmune syndromes [7]. Until the late 1980s, it was
generally believed that syngeneic HCT would have no effect on AD pathogenesis
.
Frederick R. Appelbaum, Stephen J. Forman, Robert S. Negrin, 2011
5
Analyzing T Cell Responses: How to analyze cellular immune ...
Early studies suggesting the response to syngeneic tumors (e.g. chemically
induced fibrosarcomas) is cell-mediated were carried out by George Klein and
his associates. They found that mixing tumor cells with lymphocytes from
syngeneic ...
Dirk Nagorsen, Francesco M. Marincola, 2006
6
Natural Immunity to Normal Hemopoietic Cells
the lymph nodes and that recovered from the liver of syngeneic hosts, and a good
quality suspension is typically associated with a high level of LNR and a
relatively low liver label.8 When the donor lymphocytes are damaged prior to i.v.
...
7
T-Lymphocytes and Their Receptors in Immunologic Recognition
Although T cells proliferating in human syngeneic MLC do not differ in phenotype
from helper T cells, they make up only a small fraction (6%-9%) of the total T-cell
population and can be separated from other T cells as they express the TQ1 ...
8
Tumor Models in Cancer Research
Chapter. 3. Transplantable. Syngeneic. Rodent. Tumors: Solid. Tumors. in. Mice.
Lisa Polin, Thomas H. Corbett, Bill J. Roberts, Alfred J. Lawson, Wilbur R.
Leopold III, Kathryn White, Juiwanna Kushner, Stuart Hazeldine, Richard Moore,
James ...
The 5TMM series of syngeneic murine models were originally developed by Radl
et al. [1]. Multiple myeloma was shown to develop spontaneously, at a frequency
of 0.5%, in inbred C57BL/KaLwRij mice that were older than 2 years. Myeloma ...
10
The Immunological Barriers to Regenerative Medicine
Table 2.1 Summary of previous studies demonstrating immune rejection of
transplanted ES cells Cell type Transplant Transplant site Results Ref tYP¢(S)
mES cells: undifferentiated I Syngeneic Intramyocardial I Increasing infiltration of
graft by ...
WIADOMOŚCI, KTÓRE ZAWIERAJĄ SŁOWO «SYNGENEIC»
Sprawdź, o czym dyskutuje się w prasie krajowej i zagranicznej oraz jak jest stosowane słowo
syngeneic w wiadomościach.
Asia Pacific to Dominate the Global Stem Cell Market - Vericel …
... Cell Therapy, Syngeneic Stem Cell Therapy) and Geography (North America, Europe, Asia Pacific, Middle East & Africa, Latin America and Rest of the World). «MarketWatch, Lip 15»
Thymoquinone enhances cisplatin-response through direct tumor …
... through direct tumor effects in a syngeneic mouse model of ovarian cancer ... in cultured ovarian cancer cells and in an established murine syngeneic model ... «7thSpace Interactive, Lip 15»
Calithera Biosciences Selects Immuno-Oncology Clinical Candidate …
Calithera has discovered novel, orally active arginase inhibitors that have shown inhibition of tumor growth in immunocompetent syngeneic mice. This inhibition ... «GlobeNewswire, Cze 15»
Therapeutic resistance Fibroblasts restrain drug sensitivity
... BRAF-V600E-mutant mouse melanoma cell lines were sensitive to the BRAF-V600E inhibitor PLX4720 in vitro, but when grown as syngeneic tumours in vivo, ... «Nature.com, Maj 15»
MiR-34a Link to PD-L1 May Mean New Immunotherapy in NSCLC
The delivery of miR-34a in the form of MRX34 to the syngeneic mouse model resulted in increased levels of CD8+ TILs and reduced levels of CD8+ PD-1+ cells. «Targeted Oncology, Maj 15»
6 Department of Molecular and Cellular Physiology, Louisiana State …
Blockade of CCR7, or treatment with a p38 MAP kinase inhibitor, reduced lymphatic dissemination of EMT cells in syngeneic mice. On the other hand, TGF-β1 ... «Nature.com, Maj 15»
Curis Presents Preclinical Data on CUDC-427 at AACR Annual …
... vivo studies where daily dosing of CUDC-427 induced tumor regression or stasis in certain DLBCL xenograft and B-cell lymphoma syngeneic mouse models. «GlobeNewswire, Kwi 15»
Better Tools for Improved Immuno-Oncology Research
Syngeneic models use a tumor and host that are of rodent origin, requiring mouse variants of the biologics being tested. Patient-derived tumor xenografts (PDXs) ... «Genetic Engineering & Biotechnology News, Mar 15»
Lycera to Present at the 2015 American Association for Cancer …
These activities translate into robust anti-tumor effects in syngeneic tumor models and represent a promising approach for the treatment of cancer. Authors: Xiao ... «PR Newswire, Mar 15»
New Data Investigating Merck's KEYTRUDA® (pembrolizumab) in …
(Abstract #1328) Poster Presentation: Molecular characterization of mouse syngeneic tumor models in response to treatment with anti-PD-1 immunotherapy. «Business Wire, Mar 15»
