CO OZNACZA SŁOWO THALIDOMIDE
Talidomid
Talalidomid jest lekiem immunomodulacyjnym i prototypem klasy leków talidomidowych. Został on po raz pierwszy wprowadzony do obrotu w 1957 r. W zachodnich Niemczech pod marką handlową Contergan. Niemiecka firma farmaceutyczna Chemie Grünenthal opracowała i sprzedała lek. Początkowo przepisywany jako środek uspokajający lub hipnotyczny, talidomid twierdził również, że leczy się "lęk, bezsenność, zapalenie żołądka i napięcie", później stosowano ją przeciw nudnościom i łagodzeniu porannej choroby u kobiet w ciąży. 1, 1957. Wkrótce po sprzedaży leku, w Niemczech, urodziło się od 5.000 do 7.000 niemowląt, u których stwierdzono uraz w kończynach, a 40% tych dzieci przeżyło. Na całym świecie odnotowano około 10 000 przypadków niemowląt z fokomelią z powodu talidomid, a tylko 50% spośród 10 000 pacjentów przeżyło, u których poddawano talidomid, podczas gdy w łonie matki doświadczały niedoskonałości kończyn w taki sposób, że długie kończyny nie były rozwinięte lub stawały się kikutami, a także inne zniekształcone oczy i serca, zdeformowane pokarmowe i moczowe ślady i głuchota.
Definicja słowa thalidomide w słowniku
Definicja talidomidu w słowniku jest syntetycznym lekiem stosowanym dawniej jako środek uspokajający i nasennym, ale wycofanym z rynku, gdy stwierdzono, że powoduje nieprawidłowości w rozwoju płodu. Wzór: C13H10N2O4.
KSIĄŻKI POWIĄZANE ZE SŁOWEM «THALIDOMIDE»
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1
Dark Remedy: The Impact Of
Thalidomide And Its Revival As A ...
A parable about compassion-and the absence of it-Dark Remedy is a gripping account of thalidomide's extraordinary impact on the lives of individuals and nations over half a century.
Trent Stephens, Rock Brynner,
2009
2
Dark Remedy: The Impact of Thalidomide and Its Revival as a ...
A study of thalidomide, a sedatuve that maimed and killed thousands and caused untold birth defects during the 1950s, describes how the drug has made a dramatic comeback to provide a successful treatment for millions of people with ...
Trent D. Stephens, Rock Brynner,
2001
3
Dark Remedy: The Impact of Thalidomide and Its Revival As a ...
Describes how thalidomide, a sedative that killed thousands and caused untold birth defects during the 1950s, has made a dramatic comeback to provide successful treatment for millions of people with arthritis, lupus, brain tumors, cancer, ...
Trent D. Stephens, Rock Brynner,
2001
4
Angiogenesis: An Integrative Approach from Science to Medicine
Structure of thalidomide and its IMiD derivatives. The thalidomide structure (a)
was modified by adding an amino (NH2-) group at the 4 position of the phthaloyl
ring to generate the IMiDs CC-5013 and CC-4047 (b). For CC-5013, one of the ...
William Figg, Judah Folkman,
2008
5
Giving
Thalidomide a Second Chance
Thalidomide is not approved for use in the United States; however, in appropriate
circumstances FDA allows restricted investigational use of the drug to treat the
diseases now under clinical trials. Over the vears. thalidomide has been given to
...
6
Encyclopedia of Special Education
Thalidomide was widely distributed in Europe, where it is estimated to have
affected over 7,000 individuals. It was withdrawn from the market in late 1961
before it passed Food and Drug Administration approval in the United States (
Moore, ...
Cecil R. Reynolds, Elaine Fletcher-Janzen,
2007
mentioned. Thalidomide neuropathy has not therefore been excluded. And
statements such as Dr Waters's "we have not observed any evidence of
thalidomide neurotoxicity" (Leprosy Review, vol 42, p 26) have little meaning. No
case of ...
8
Encyclopedia of Women's Health
Thalidomide women with severe morning sickness. It was advertised as a
nontoxic medication, with no side effects, and completely safe for pregnant
women. All of these claims were untrue. A major side effect associated with long-
term use is ...
Sana Loue, Martha Sajatovic, Keith B. Armitage,
2004
9
Drugs in Pregnancy and Lactation: A Reference Guide to Fetal ...
JAMA 1962:180:1106-14. 23. Lenz W. Thalidomide and congenital abnormalities
. Lancet 1962: 1:45. 24. McBride WG. Thalidomide and congenital abnormalities.
Lancet 1961:2:1358. 25. Pfeiffer RA, Kosenow W. Thalidomide and congenital ...
Gerald G. Briggs, Roger K. Freeman, Sumner J. Yaffe,
2008
10
Syndromes of the Head and Neck
Thalidomide embryopathy.(A) Midfacial hemangioma. (B,C) Phocomelia of both
arms, absent ears. Patient also had ankylosis of temporomandibular joint, bifid
uvula, and absence of one parotid gland. Mother had consists of mild enamel ...
M.S. D.Sc. Regents' Professor Emeritus of Oral Pathology and Genetics at School of Dentistry Robert J. Gorlin D.D.S, D.M.D. M. Michael Cohen Jr., Ph.D. Professor Oral Pathology Faculty of Denistry, Ph.D. Department of Pediatrics and Medical Genetics Raoul C.M. Hennekam M.D., Academic Medical Center University of Amsterdam,
2001
WIADOMOŚCI, KTÓRE ZAWIERAJĄ SŁOWO «THALIDOMIDE»
Sprawdź, o czym dyskutuje się w prasie krajowej i zagranicznej oraz jak jest stosowane słowo
thalidomide w wiadomościach.
Globe wins Michener Award for series on thalidomide drug survivors
Nine days after The Globe first published, thalidomide victims met with the federal government, which voted in a rare display of of unanimity to support ... «The Globe and Mail, Cze 15»
New film about Thalidomide victim
Award-winning documentary maker Roger Graef has signed up to make a new film about a Thalidomide victim half a century after he first told his story. «Belfast Telegraph, Cze 15»
For Canadian thalidomide victims, compensation is fair but long …
But the victims of thalidomide now have some redress, some peace of mind in their final years. Late Friday, Health Minister Rona Ambrose announced the ... «The Globe and Mail, Maj 15»
No answers from Ottawa on financial support for thalidomide survivors
Victims of the drug thalidomide came away from a two-hour meeting with Health Canada on Monday voicing “grave concerns” over Ottawa's failure to provide ... «The Globe and Mail, Kwi 15»
Thalidomide survivors want clarity on federal compensation package
A group of Canadian thalidomide survivors is in Ottawa today to get more ... executive director of the Thalidomide Victim's Association, said members of her ... «CBC.ca, Mar 15»
Thalidomide survivors to receive $125000 lump sum payment each
The federal government is offering a $125,000 lump-sum payment to each of Canada's thalidomide victims, but the family of one survivor says it isn't enough. «CBC.ca, Mar 15»
Ottawa to miss deadline for thalidomide victims' financial aid
The federal government will not meet the Monday deadline set by the Thalidomide Victims Association of Canada to announce a financial aid package for ... «The Globe and Mail, Sty 15»
Thalidomide Victims In Spain Still Waiting For Compensation
More than five decades on, the battle for justice over birth defects caused by the drug thalidomide continues in only one European country: Spain. Spanish ... «NPR, Gru 14»
Parliamentary motion for 'full support' for thalidomide survivors …
Members of Parliament rose as one to applaud Canada's thalidomide victims on Monday, and up in the visitors' gallery, the victims watched and wept. As MPs ... «The Globe and Mail, Gru 14»
Former minister says 1991 thalidomide package was 'as generous …
The federal health minister who reached the 1991 compensation deal with Canadian thalidomide victims says he sought as generous a package as possible, ... «The Globe and Mail, Lis 14»