KSIĄŻKI POWIĄZANE ZE SŁOWEM «TUMORIGENICITY»
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1
Process Validation in Manufacturing of Biopharmaceuticals: ...
Due to concerns related to the presence of activated oncogenes or tumorigenic
viruses in these cells, requirements for in vivo and/or in vitro tumorigenicity
assays were established for cell lines. In 1993, the U.S. FDA discontinued the ...
2
Handbook of Laboratory Animal Science
The difference should be kept in mind when working with tumor transplantation in
this model. Tumorigenicity Based on observations of extensive materials, it is
obvious that some tumor types are extremely difficult to establish in nude mice,
and ...
Jann Hau, Per Svendsen, Steven J. Schapiro, 1994
tumorigenicity, or an induced transformation during the course of the
tumorigenicity assay. Reliable methods for distinguishing between these
alternatives do not presently exist. Two Of the established lines most frequently
used as normal ...
4
Drug Biotechnology Regulation: Scientific Basis and Practices
E. Tumorigenicity The Points to Consider recommends that the cell line (WCB) he
tested for tumorigenicity [2]. 1t also states that a positive result from the
tumorigenicity test will not necessarily prevent the qualification of the cell line as
a ...
5
The Nude Mouse in Experimental and Clinical Research
tial existed for the use of this animal as a model system for the assay of cellular
tumorigenicity. Giovanella et al. (1973, 1974) began studies along these lines
with an investigation of the tumorigenicity of cell lines derived from human
malignant ...
6
Genetic Analysis of Tumour Suppression
In addition, such studies may provide considerable information on the interaction
of tumorigenicity-promoting genes. Some of the hybrids in the experiment just
described with Wilms' cells are much more tumorigenic than the parental D98
cells ...
CIBA Foundation Symposium, 2008
7
Transformation of Human Epithelial CellsMolecular and ...
into Wilms' tumor cells suppresses the tumorigenicity of these cells. 8- Likewise,
Barrett, Oshimura, and co-workers have observed similar suppression in cervical
carcinoma cell lines,8384 as have Stanbridge et al., using HeLa cells.85 In ...
George E. Milo, Bruce C. Casto, Charles F. Shuler, 1992
8
Encyclopedia of Environmetrics
Constant risk differences in the analysis of animal tumorigenicity data. Biometrics
47, 681-700. [12] Dinse, G. (1998). Tumor incidence experiments, in
Encyclopedia of Biostatistics, Vol. 6, P. Armitage & T. Colton, eds, John Wiley,
Chichester.
Abdel H. El-Shaarawi, Walter W. Piegorsch, 2001
9
Prostate Cancer: New Insights for the Healthcare ...
In mouse models, Pim1 is known to cooperate with c-Myc to promote
tumorigenicity,” investigators in the United States report. “However, there has
been limited analysis of the tumorigenic potential of Pim1 overexpression in
benign and ...
10
Cell Biology, Four-Volume Set: A Laboratory Handbook
Tumorigenicity is defined as the ability of viable cultured cells to give rise to
progressively growing tumor nodules, showing viable and mitotically active cells,
in immunologically nonresponsive animals over a limited observation period (
WHO, ...
Julio E. Celis, Nigel Carter, Kai Simons, 2005
WIADOMOŚCI, KTÓRE ZAWIERAJĄ SŁOWO «TUMORIGENICITY»
Sprawdź, o czym dyskutuje się w prasie krajowej i zagranicznej oraz jak jest stosowane słowo
tumorigenicity w wiadomościach.
International Stem Cell Corporation Submits Remaining Requested …
... announced today the submission of the final safety (tumorigenicity) and biodistribution study report that has been requested by the Australian Therapeutics ... «CNNMoney, Lip 15»
B7-H3 silencing by RNAi inhibits tumor progression and enhances …
U937 xenograft models were used to assess the effects of B7-H3 on tumorigenicity and the therapeutic effect of B7-H3 knockdown in combination with ... «Dove Medical Press, Lip 15»
Mitochondria control oncogenesis through metabolic reprogramming
Tumorigenicity was found to be suppressed when the cytoplasm of enucleated normal cells was fused with nucleated tumor cells. In other words normal ... «Medical Xpress, Lip 15»
Independent Data Safety and Monitoring Board Recommends …
Expression of EGFRvIII correlates with increased tumorigenicity in mouse models and poor long term survival in clinical studies of patients with glioblastoma ... «GlobeNewswire, Cze 15»
The oncogenic role of the cochaperone Sgt1
To test the effect of Sgt1 reduction on tumorigenicity, we conducted an allograft experiment in which Hras-transduced Sgt1+/+ p53−/− and Sgt1+/− p53−/− MEF ... «Nature.com, Maj 15»
Pharmacological targeting of guanosine monophosphate synthase …
However, because of the newly revealed importance of guanylate metabolism in control of melanoma cell invasion and tumorigenicity, GMPS emerges as an ... «Nature.com, Kwi 15»
OncoMed Presents Data on Clinical and Preclinical Anti-Cancer …
"Tarextumab (Anti-NOTCH2/3) reverses NOTCH2 and NOTCH3-dependent tumorigenicity and metastases in small cell lung cancer" (Abstract number: 2323) ... «GlobeNewswire, Kwi 15»
Melanoma Metastatic Potential is Fuelled by CXCR3 Signaling
... CXCR3 induced the expression of IL-8, which has been previously shown to significantly increase RGP melanoma tumorigenicity and metastatic potential. «Melanoma News Today, Kwi 15»
PIM Kinase Inhibitor AZD1208 for Treatment of MYC-Driven Prostate …
Background PIM1 kinase is coexpressed with c-MYC in human prostate cancers (PCs) and dramatically enhances c-MYC-induced tumorigenicity. Here we ... «Medscape, Lut 15»
Editorial: A new checkpoint in the path to GVHD? How bedside-to …
Out of this has emerged suppression of tumorigenicity 2 (ST2) as the single-most accurate predictor of GVHD incidence severity and associated mortality that ... «Journal of Leukocyte Biology, Lut 15»
