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1
The Chemokine Factsbook: Ligands and Receptors
О )urkat cells stably transfected with IL-8RB bind IL-8, Kd = 3—5 nM4. ° Iurkat cells stably expressing IL-8RB chemotax in response to IL-8, GRO-ot and NAP-23. ° GTP-)IS activation of 3ASubE cells expressing IL-8RB is PT-sensitiveó.
Krishna Vaddi, Margaret Keller, Matthew Newton,
1997
2
The Challenge of Highly Pathogenic Microorganisms: ... - Halaman 128
The failure to bind IL-1ra was logical if the purpose of the virus protein was to block IL-1 mediated signal transduction, but the failure to bind IL-1α was unexpected and indicated that the inhibition of IL-1β was more important for the virus.
Baruch Velan, Avigdor Shafferman, Arie Ordentlich,
2010
3
Leukocyte and Stromal Cell Molecules: The CD Markers - Halaman 357
CDw210b does not bind IL-10 directly, but the functional receptor appears to be a tetramer containing two molecules of CDw210a and two of CDw210b. CDw210b binds IL-22 directly with high affinity, and binding has been reported to IL-26, ...
Moreover, the soluble IL-4 receptor was effectively purified by an IL-4 affinity column.25 These results indicate that a soluble IL-4 receptor is able to bind IL-4 efficiently. Reduction of the soluble IL-4 receptor by dithiothreitol caused a loss of ...
5
Algorithms for Image Processing and Computer Vision - Halaman 92
The program, which will be called BinDil, reads the names of three files from standard input: BinDil Enter input image filename: squares.pbm Enter structuring element filename: simple.pbm Enter output filename: xx.pbm whereupon the ...
6
Human Molecular Biology: An Introduction to the Molecular ...
The homodimeric receptor family: bind EPO, GH, prolactin, and G-CSF. 2. The 130-kDa 3-chain (gp130) receptor family: bind IL-6, IL-11, LIF, oncostatin M, and CNTF. 3. The 140-kDa B-chain receptor family: bind IL-3, IL-5, and GM-CSF. 4.
7
Cytokine Therapies - Halaman 125
We hypothesized that creating a soluble receptor containing both receptor components would bind IL-1 with high affinity, forming a potent antagonist. We created heterodimeric proteins by fusing each extracellular domain to the Fc portion of ...
Raymond P. Donnelly,
2010
8
Colony-Stimulating Factors: Molecular & Cellular Biology, ...
Although the common β-subunit is unable to bind IL-3, IL-5, or GM-CSF when expressed alone, the IL-3-specific p-subunit binds IL-3 with low affinity (21). In vitro, however, both p-subunits appear to produce analogous signals (19).
9
Fundamental Immunology - Halaman 766
On the surface of the cell, IL-1RII, a decoy receptor, may also bind IL-1B (13), but this complex does not recruit IL-1RAcP and there is no signal. In the extracellular space, the extracellular domains (soluble or sIL-1RII) of the IL-1RII bind IL-16 ...
10
Eosinophils in Health and Disease - Halaman 100
Complementary DNA coding for soluble forms of both mIL-5RA and hIL-5RA subunits have been isolated.36,37 CD99-cos7 transfectants expressing recombinant mIL-5RA bind IL-5 with low affinity. The recombinant hIL-5RA subunit ...
James J. Lee, Helene F. Rosenberg,
2012