CE ÎNSEAMNĂ POLYMYXIN ÎN ENGLEZĂ?
Polimyxin
Polimixinele sunt antibiotice, cu o structură generală constând dintr-o peptidă ciclică cu coadă lungă hidrofobă. Ele perturbe structura membranei celulare bacteriene prin interacțiunea cu fosfolipidele sale. Acestea sunt produse de sisteme de sintetază peptidică nonribozomală în bacterii gram-pozitive cum ar fi Paenibacillus polymyxa și sunt selectiv toxice pentru bacteriile Gram-negative datorită specificității lor pentru molecula de lipopolizaharidă care există în multe membrane externe gram-negative. Polimixinele B și E sunt utilizate în tratamentul infecțiilor bacteriene gram-negative. Problema globală de avansare a rezistenței antimicrobiene a condus la un interes din ce în ce mai recent în utilizarea lor. Polimixina M este, de asemenea, cunoscută sub numele de "mattacin".
Definiția polymyxin în dicționarul Engleză
Definiția polimixinei în dicționar este oricare dintre mai multe antibiotice polipeptidice active împotriva bacteriilor gram-negative, obținute de la bacteria solului Bacillus polymyxa.
CĂRȚI ÎN ENGLEZĂ ÎN LEGĂTURĂ CU «POLYMYXIN»
Descoperă întrebuințarea
polymyxin în următoarea selecție bibliografică. Cărți în legătură cu
polymyxin și extrase din aceasta pentru a furniza contextul de întrebuințare al acestuia în literatura Engleză.
1
Equine Infectious Diseases
Assuming that the underlying cause of endotoxemia can be corrected, the benefit
of administering polymyxin B is likely limited to the first 24 to 48 hours of
treatment, and prolonged use is not expected to provide additional advantages.
96 ...
Debra C. Sellon, Maureen Long,
2013
2
Critical Care Nephrology
Polymyxins. Polymyxins constitute a class of antibiotics, discovered in the late
1940s, characterized by their extreme efficiency against gram-negative bacteria.
Of the five polymyxins (A, B, C, D, and E), only polymyxin B and polymixin ...
Claudio Ronco, Rinaldo Bellomo, John A. Kellum,
2008
3
Veterinary Pharmacology and Therapeutics
The largest use of polymyxin has been in topical ointment preparations.
Polymyxin B sulfate is a mixture of polymyxin Bl (C5gH98N16O3) and polymyxin
B2 (CjjHggNjgO^); polymyxin E is more commonly known as colistin (Harvey
1985).
Jim E. Riviere, Mark G. Papich,
2013
4
Remington: The Science and Practice of Pharmacy
It usually is combined with neomycin and polymyxin B sulfate. Development of
bacterial resistance is much less frequent and slower for bacitracin than for
penicillin, and for most organisms it is essentially nil. In addition to renal damage,
toxic ...
David B. Troy, Paul Beringer,
2006
5
Disinfection, Sterilization, and Preservation
Eradication of MRS A with bacitracin-polymyxin B-gramicidin was successful in 9
of 1 1 patients. Bacitracin-polymyxin-neoinycin ointments have been used for
many years as prophylactic antiseptic agents for the prevention of catheter-
related ...
Seymour Stanton Block,
2001
Cortisporin Otic Suspension contains neo- mycin sulfate, polymyxin B,
hydrocortisone, cetyl alcohol, propylene glycol, polysorbate 80, and thimerosal. 4
. Pedi-Otic Suspension contains the same ingredients as Cortisporin Otic
Suspension with ...
Peter S. Roland, John A. Rutka,
2004
7
The Handbook of Microbiological Media for the Examination of ...
Preparation of Medium: Add components—ex- cept egg yolk emulsion, 50%, and
polymyxin B solution—to distilled/deionized water and bring volume to 940.0mL.
Mix thoroughly. Gently heat and bring to boiling. Autoclave for 15 min at 15 psi ...
8
Fisher's Contact Dermatitis
This was inhibited by a simultaneous local injection of the antihistamine
mepyramine, which also abolished the vascular response to histamine and to the
histamine liberator polymyxin B. Depletion of cutaneous histamine by
pretreatment with ...
Robert L. Rietschel, Alexander A. Fisher, Joseph F. Fowler,
2008
9
The Antimicrobial Drugs
Changes in cellular permeability as a result of exposure to polymyxin have also
been demonstrated with a dye compound. The dye N-toly-ot-napthylamine-
8sulfonic acid fluoresces under ultraviolet light when it is bound to protein.
Eric M. Scholar Associate Professor of Pharmacology University of Nebraska College of Medicine, William B. Pratt Professor of Pharmacology University of Michigan Medical School,
2000
10
L.S.A., List of C.F.R. Sections Affected
(6) Bacitracin zinc-polymyxin B sulfate ointment containing, in each gram, 500
units of bacitracin and 10,000 units of polymyxin B in a suitable ointment base. (7
) Bacitracin zinc-polymyxin B sulfate topical aerosol containing, in each gram,
120 ...
ȘTIRI NOI CARE INCLUD TERMENUL «POLYMYXIN»
Află ce ziare naționale și internaționale au scris despre și cum este întrebuințat termenul
polymyxin în contextul următoarelor știri.
Wayne State to Lead $4.8 Million NIH Study That Will Teach an Old …
The study, “Optimizing clinical use of polymyxin B: teaching an old drug to treat superbugs,” will focus on Gram-negative bacteria resistant to all ... «Newswise, Iul 15»
Prevention of Infection in Cataract Surgery Gets Easier Regimen
A team of researchers lead by Dr. Martin Nentwich compared the effect of applying a solution of neomycin/polymyxin-B eye drops (antibiotics), ... «Cataract News Today, Iun 15»
Sepsis caused by Listeria monocytogenes during chemotherapy for …
In addition, to control immuno-responsiveness, endotoxin adsorption with blood adsorption therapy using a polymyxin B column was reported ... «BMC Blogs Network, Iun 15»
Novel bio-inspired antibiotic compound series created
"The main goal of the study has been to design, synthetize and prove in vitro activity and in vivo toxicity of a new series of polymyxin, which ... «Vaccine News Daily, Iun 15»
Researchers develop a new family of bioinspired antibiotic …
"The main goal of the study has been to design, synthetize and prove in vitro activity and in vivo toxicity of a new series of polymyxin, which ... «Phys.Org, Iun 15»
Antibiotic prophylaxis 1 day or 1 hour before surgery reduces …
Sixty-four eyes (group 1) received four applications of topical 3,500 IU/mL of neomycin sulfate, 6,000 IU/mL of polymyxin B sulfate plus 1 mg/mL ... «Healio, Iun 15»
Drug development critical to combating antibiotic resistance
Polymyxin B is a good example of this, she said. Largely abandoned because of its toxicity, polymyxin B is demonstrating effectiveness against some resistant ... «Healio, Iun 15»
An 8-year-old made this creepy handprint that gives a whole new …
Scientists use some of these species to synthesize antibiotics like bacitracin and polymyxin and while some can cause illness, most are are ... «Business Insider, Iun 15»
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After dialysis against the Tris-HCl buffer, the sample was further purified to remove endotoxin by polymyxin B column (Bio-Rad, USA). «BMC Blogs Network, Iun 15»
Synereca Pharmaceuticals Appoints Dr. Mark Corrigan to Its Board …
... (polymyxin E, colistimethate sodium) for the treatment of serious hospital-associated infections caused by resistant Gram-Negative bacteria, ... «PR Newswire, Mai 15»