ЧТО ОЗНАЧАЕТ СЛОВО HYDROXYUREA
Гидроксикарбамид
Гидроксикарбамид или гидроксимочевина представляет собой противоопухолевое лекарственное средство, впервые синтезированное в 1869 году, используемое при миелопролиферативных нарушениях, в частности, полицитемии и существенной тромбоцитемии. Он также используется для снижения частоты болевых приступов при серповидноклеточной болезни и обладает антиретровирусными свойствами при таких заболеваниях, как СПИД. Он относится к Перечню основных лекарственных средств Всемирной организации здравоохранения, который содержит список наиболее важных лекарств, необходимых для базовой системы здравоохранения.
Значение слова hydroxyurea в словаре английский языка
Определение гидроксимочевины в словаре - это препарат, который предотвращает развитие опухолей и используется для лечения определенных видов рака, а также для лечения серповидноклеточных заболеваний и СПИДа.
КНИГИ НА АНГЛИЙСКИЙ ЯЗЫКЕ, ИМЕЮЩЕЕ ОТНОШЕНИЕ К СЛОВУ «HYDROXYUREA»
Поиск случаев использования слова
hydroxyurea в следующих библиографических источниках. Книги, относящиеся к слову
hydroxyurea, и краткие выдержки из этих книг для получения представления о контексте использования этого слова в литературе на английский языке.
1
Defining a Novel Role of
Hydroxyurea on Erythrocytes
Recent findings implicate the red blood cell (RBC) as a determinant in physiological events that regulate the blood flow in the circulatory system.
Madushi Upendrika Raththagala,
2008
2
The AARP Guide to Pills: Essential Information on More Than ...
Hydroxyurea is a medicine that must be handled with care. People who are not
taking hydroxyurea should not be exposed to the powder in the open capsules. If
the powder from the capsule is spilled, it should be wiped up immediately with a ...
3
Meningiomas: Diagnosis, Treatment, and Outcome
Hydroxyurea is an antimetabolite that is orally absorbed, which allows ease of
administration. Its effects appear to be specific to the S phase of the cell cycle.
The molecular target is likely DNA synthesis mechanisms, and the drug causes ...
4
Drugs in Pregnancy and Lactation: A Reference Guide to Fetal ...
Antineoplastic PREGNANCY RECOMMENDATION: Limited Human Data -
Animal Data Suggest Risk BREASTFEEDING RECOMMENDATION:
Contraindicated PREGNANCY SUMMARY Although hydroxyurea is teratogenic
in animals, ...
Gerald G. Briggs, Roger K. Freeman, Sumner J. Yaffe,
2011
5
Disorders of Hemoglobin: Genetics, Pathophysiology, and ...
when hydroxyurea is used in myeloproliferative disorders. How and if the
myeloproliferative disorders equate to a disease without cancer-promoting
mutations but with lifelong expanded erythropoiesis remains to be seen. Acute
leukemia has ...
Martin H. Steinberg,
2001
6
HIV Chemotherapy: A Critical Review
Several pilot studies that examined the safety and efficacy of hydroxyurea
demonstrated that hydroxyurea monotherapy was not effective in decreasing
plasma HIV RNA, but in combination with didanosine a significant reductions in
viral load ...
Salvatore T. Butera,
2005
7
Frontiers in Medicinal Chemistry , Volume (4)
HYDROXYUREA PHARMACOKINETICS AND METABOLISM The
pharmacokinetics and pharmacodynamics of hydroxyurea have recently been
reviewed [20]. In general, hydroxyurea crosses the intestinal wall easily and
demonstrates ...
Atta-ur-Rahman, Allen B. Reitz, M. Iqbal Choudhary,
2009
8
Nitric Oxide Donors: For Pharmaceutical and Biological ...
0.15 mM hydroxyurea solution decomposes after 9 months at 4°C in neutral
aqueous solution [105]. Hydroxyurea also does not decompose in alkaline
solutions (pH 14, 30 min, 25°C) or in acidic conditions (pH 1–1.5, 3 h, 25°C) but
hydrolyzes ...
Peng George Wang, Tingwei Bill Cai, Naoyuki Taniguchi,
2005
9
Evidence-Based Hematology
Introduction Hydroxyurea is the only medication approved by the U.S. Food and
Drug Administration to treat SCD. The exact mechanism(s) of action resulting in
beneficial effects in SCD is not known. In addition to increasing fetal hemoglobin
...
Mark A. Crowther, Jeffrey Ginsberg, Holger Schünemann,
2009
10
Wintrobe's Clinical Hematology
Figure 33.12. effect of hydroxyurea on red blood cells. A. Peripheral blood smear
of patient with Hb SS prior to treatment with hydroxyurea showing sickle forms (
solid arrow), polychromasia, Howell-Jolly body (dashed arrow), and anisocytosis.
John P. Greer, Daniel A. Arber, Bertil Glader,
2013
НОВОСТИ, В КОТОРЫХ ВСТРЕЧАЕТСЯ ТЕРМИН «HYDROXYUREA»
Здесь показано, как национальная и международная пресса использует термин
hydroxyurea в контексте приведенных ниже новостных статей.
New Drug Offers Hope for Sickle Cell Patients
It uses a drug called hydroxyurea. The drug is already widely used in the U.S, but at Mulago it is still undergoing clinical trials. Kiragga and his ... «AllAfrica.com, Июл 15»
Third Rock's GBT swings for a $115M IPO to push its pill for sickle cell
Standard treatment for the disease relies on toxic treatments like hydroxyurea, or inconvenient blood transfusions and bone marrow transplants ... «FierceBiotech, Июл 15»
Screen children early for sickle cell disease
Dr Osei-Tutu hinted that plans were far advanced to have hydroxyurea (a drug for sickle-cell patients) on the National Health Insurance drug list ... «Graphic Online, Июл 15»
The Regulatory Quagmire Of Treatments For Sickle Cell Disease
Hydroxyurea is being studied in pediatric patients under the National Institute for Child Health And Human Development's (NICHD) program, ... «Forbes, Июл 15»
Ruxolitinib is useful for long-term treatment of polycythemia vera
In the study, 222 patients who were intolerant or resistant to hydroxyurea were randomized to open-label ruxolitinib 10 mg BID or best available ... «Medical News Today, Июн 15»
Persons with sickle cell disease can now benefit from NHF
"He got a stroke when he was five and they put him on hydroxyurea after that, so it is quite expensive. "And he has to do physiotherapy and stuff ... «Jamaica Observer, Июн 15»
CSCF observes World Sickle Cell Day
Through the initiative, approximately 20 percent more individuals suffering from the disease have been able to access Hydroxyurea, the only ... «New Pittsburgh Courier, Июн 15»
Federal employees honored for innovation
Rodgers' first major contribution to sickle cell research was work on developing a drug, hydroxyurea, which is used to treat it. Now his team at ... «Baltimore Sun, Июн 15»
Sickle Cell Disease and Clinical Trials
Hydroxyurea: Patients can take this oral medication to help reduce the frequency of pain crises and the need for blood transfusions. «FDA.gov, Июн 15»
Sickle Cell Is a Hereditary Disease of the Blood
A compound hydroxyurea reduces the frequency of painful crises possibly by stimulating the body to continue producing foetal haemoglobin, ... «AllAfrica.com, Июн 15»