КНИГИ НА АНГЛИЙСКИЙ ЯЗЫКЕ, ИМЕЮЩЕЕ ОТНОШЕНИЕ К СЛОВУ «MEFLOQUINE»
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CHAPTER 10.4 MEFLOQUINE PATRICIA SCHLAGENHAUF-LAWLOR Abstract
Mefloquine is a widely used, orally administered blood schizonticide for the
chemoprophylaxis of malaria. Steady-state pharmacokinetics of weekly
prophylaxis in ...
Patricia Schlagenhauf-Lawlor, 2008
2
Pharmacotherapeutics for Advanced Practice: A Practical Approach
Mefloquine Mefloquine, a4-quinolinemethanol derivative, is chemically related to
quinine. In chloroquine-resistant areas, meflo- quine is the drug of choice. As a
blood schizonticide, it prevents the replication of erythrocytic parasites but has no
...
Virginia Poole Arcangelo, Andrew M. Peterson, 2006
3
The Antimicrobial Drugs
Mefloquine interacts relatively weakly with free heme and has been shown to
inhibit heme polymerization in vitro with a similar or lower efficiency than
chloroquine.5“*“"'*'1'9 Given the lower basicity of mefloquine, it seems unlikely
that it would ...
Eric M. Scholar Associate Professor of Pharmacology University of Nebraska College of Medicine, William B. Pratt Professor of Pharmacology University of Michigan Medical School, 2000
4
Drug Design, Molecular Modelling, and QSAR Studies of ...
... Table 3.2 Regression model for 20 mefloquine derivatives using all functional
group indicator variables ....................................................................................................
...............................................................26 Table 3.3 Activity, Estimate and Residual ...
THE WORLD Health Organization has warned that the new antimalarial drug,
mefloquine, may cause severe mental disturbances and other psychiatric or
neurological side effects. Airline pilots and others whose jobs involve "fine
coordination ...
6
Side Effects of Drugs Annual: A worldwide yearly survey of ...
Mefloquine (SED-15, 2232) Psychiatry Mefloquine is generally safe but has been
plagued by continued reports of neuropsychiatric disturbances, such as dizziness
and anxiety. It is used mainly as prophylaxis by travellers to malaria endemic ...
7
Textbook Of Pharmacology
DRUG THERAPY OF MALARIA However, resistant organisms accumulate less
mefloquine. Both these drugs produce similar morphological changes in
erythrocytic ring stages of P. falciparum and P. xnvax. Mefloquine probably forms
a toxic ...
8
Integrating and Articulating Environments
(2003) described the tolerability of mefloquine relative to doxycycline,
atovaquone–proguanil, and chloroquine–proguanil in 623 nonimmune Swiss
travelers to sub-Saharan Africa (n= 153 mefloquine users). This study used a
questionnaire in ...
F. Adaman, F. Goksen, J. Grolin, 2003
9
Reemergence of Established Pathogens in the 21st Century
Mefloquine Mefloquine's mechanism of action, like chloroquine, is likely
mediated via inhibition of heme polymerization and detoxification. The precise
mechanism of drug resistance to mefloquine although unknown, appears to be
distinct from ...
I.W. Fong, Karl Drlica, 2003
10
Chirality in Drug Design and Development
Mefloquine is administered as a racemic mixture of the (−)-SR and (+)-RS
diastereomers. Mefloquine exhibits much higher plasma and blood
concentrations of the (−) enantiomer than the (+) enantiomer [36,37]. In plasma of
subjects given 250 ...
Indra K. Reddy, Reza Mehvar, 2004
НОВОСТИ, В КОТОРЫХ ВСТРЕЧАЕТСЯ ТЕРМИН «MEFLOQUINE»
Здесь показано, как национальная и международная пресса использует термин
mefloquine в контексте приведенных ниже новостных статей.
New Long-Acting Malaria Drug Looks Promising
Drugs that do treat malaria can cause serious side-effects. Mefloquine hydrochloride, sold under brand names including Lariam, Mephaquin or ... «NBCNews.com, Июл 15»
The Woman Determined to End Drug-Resistant Malaria
Resistance developed to chloroquine in the late-1950s, sulfadoxine-pyrimethamine and quinine in the mid-1960s, and mefloquine in the ... «Huffington Post, Июл 15»
Monitoring PfMDR1 transport in Plasmodium falciparum
Competition studies of Fluo-4 with chloroquine, quinine and mefloquine were performed on parasites harbouring asparagine at position 1042. «7thSpace Interactive, Июл 15»
Careful, how you use malaria drugs to prevent infection
Using “different medications for chemoprophylaxis in succession”, say using Mefloquine during the first cycle of chemoprophylaxis and then ... «The Observer, Июн 15»
Avanir Pharmaceuticals Announces Positive Top-line Results from …
... containing quinidine, quinine, or mefloquine and in patients with a known hypersensitivity to these drugs or any of NUEDEXTA's components. «Satellite PR News, Июн 15»
David Swanson: Human experimentation is a CIA habit
At Guantanamo, the CIA gave huge doses of the terror-inducing drug mefloquine to prisoners without their consent, as well as the supposed ... «Madison.com, Июн 15»
Human Experimentation
At Guantanamo, the CIA gave huge doses of the terror-inducing drug mefloquine to prisoners without their consent, as well as the supposed ... «CounterPunch, Июн 15»
New Book: Antimalarial Drugs Part of Secret Program to Torture …
Mefloquine administration was standard operating procedure upon admission. The official story, first reported to Jason Leopold and me and ... «Firedoglake, Апр 15»
Former Peace Corps Volunteer Sues over Malaria Drug
Ms. Thompson, 32, said the symptoms began during her Peace Corps service in Africa, where she took the antimalarial drug mefloquine. «Wall Street Journal, Мар 15»
Mefloquine Toxicity and Post Traumatic Stress Injury
Recently, someone asked about certain symptoms of mefloquine toxicity and Post Traumatic Stress. This isn't about the life-threatening ones, ... «ChicagoNow, Фев 15»