КНИГИ НА АНГЛИЙСКИЙ ЯЗЫКЕ, ИМЕЮЩЕЕ ОТНОШЕНИЕ К СЛОВУ «PLEIOTROPISM»
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1
The Skull, Volume 1: Development
Pleiotropism Because skeletal genes are often a long way from the primary gene
effect, they are often pleiotropic: that is, the same genes act in many tissues and
changes in such genes tend to produce a suite of changes, often expressed as a
...
James Hanken, Brian K. Hall, 1993
2
The Genetic Basis of Common Diseases
The second general feature is pleiotropism, which refers to multiple effects of a
single gene. An example of pleiotropism is the Marfan syndrome in which a
single abnormal gene can produce changes in the skeleton, eyes, heart, and
great ...
Institute of Human Genetics University of Minnesota Medical School Richard A. King Department of Medicine, Division of Medical Genetics Jerome I. Rotter Director, Cedars-Sinai Board of Governors' Chair in Medical Genetics, Arno G. Motulsky Departments of Medicine and Gerome Sciences University of Washington School of Medicine, 2002
3
Marfan Syndrome: A Primer For Clinicians And Scientists
Clinical delineation of the Marfan syndrome involved consideration of three main
principles of clinical genetics: pleiotropism (already mentioned), genetic
heterogeneity, and variability. Pleiotropism is important to clinical genetics
because one ...
Peter N. Robinson, Maurice Godfrey, 2004
4
Genetics And Plant Breeding
Pleiotropism Pleiotropism is defined as the effect of a single gene upon two or
more characters which are not related. In Drosophila, the recessive gene for
vestigial wings (vg) produces vestigial wings in homozygous condition. In
addition to ...
Autosomal dominant disorders may exhibit several important general features:
pleiotropism, variable expressivity and delayed age of onset, and variable
penetrance. PLEIOTROPISM Pleiotropism refers to the phenomenon in which
multiple, ...
6
Animal Behavior Desk Reference: A Dictionary of Animal ...
pleiotropism argument, pleiotropism hypothesis, pleiotropism theory See
hypothesis: hypothesis of divergent evolution of animal genitalia: pleiotropism
hypothesis. ♢ pleiotropy n. 1. The same gene's, or set of genes', control of more
than one of ...
7
Emery and Rimoin's Principles and Practice of Medical Genetics
The three main principles of clinical genetics (perhaps they should be called the
three main phenomena of significance to clinical genetics) are pleiotropism,
genetic heterogeneity, and variability. The history of our under— standing of each
...
David L. Rimoin, Reed E. Pyeritz, Bruce Korf, 2013
8
Victor McKusick and the History of Medical Genetics
It was Glass who impressed upon Victor that pleiotropism of a single mutant gene
was a more likely explanation for the association between polyps and spots
rather than genetic linkage. Victor's early work in cardiology is well known. Early
in ...
Krishna R. Dronamraju, Clair A. Francomano, 2012
9
Cell Biology and Genetics
1 1 6.8 What is pleiotropism ? Give some examples of pleiotropism in man.
Pleiotropism In gene interaction several genes interact to produce a character. In
contrast, a single gene may have multiple effects. When a gene causes changes
in ...
Geeta Bansal, M. C. Bhatnagar
10
Neurobehavioral Genetics: Methods and Applications
Gruneberg10 introduced the concepts of genuine and spurious pleiotropism. In
genuine pleiotropism the phenotypic effects would be the result of multiple
primary gene effects. Examples of genuine pleiotropism are difficult to determine
and ...
Byron C. Jones, Pierre Mormede, 1999
