КНИГИ НА АНГЛИЙСКИЙ ЯЗЫКЕ, ИМЕЮЩЕЕ ОТНОШЕНИЕ К СЛОВУ «THYMIDYLIC ACID»
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and glycine; they can provide the single carbon fragment necessary for the
formation of thymidylic acid, but they apparently are not intermediates in the
production of this carbon from glucose?“ Arginine is indirectly related to
pyrimidines by the ...
2
Research in Radiotherapy: Approaches to Chemical Sensitization
These extremely potent inhibitors of the enzyme system responsible for the
formation, from folic acid, first of dihydrofolic acid, and then of tetrahydrofolic acid,
affect the formation of thymidylic acid even more markedly than they do the
formation ...
3
Isotopes in Biochemistry
The specific activities of thymidylic acid were low. The specific activities of the
bases from the nucleic acids of regenerating liver are given in Table VI.
Regenerating liver has been studied because it is a rapidly growing tissue, as
are Table VI ...
CIBA Foundation Symposium, 2008
4
Hugo and Russell's Pharmaceutical Microbiology
Figure 12.5 Conversion of uridylic acid to thymidylic acid by the enzyme
thymidylate synthetase, a vital early stage in the synthesis of DNA. The antifungal
agent 5-fluorocytosine also interferes with these early stages of DNA synthesis.
Through ...
Stephen P. Denyer, Norman Hodges, Sean P. Gorman, 2011
5
Biochemical Analysis of the Mycobacterium Tuberculosis ...
Blakley, R. L., and McDougall, B. M. (1962) The biosynthesis of thymidylic acid. III
. Purification of thymidylate synthetase and its spectrophotometric assay, J Biol
Chem 237, 812-818. 2. Blakley, R. L., Ramasastri, B. V., and McDougall, B. M. (1
...
Joshua Hampton Hunter, 2008
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The Treatment of Cancer: With Special Reference to ...
The N,-u, methylene group ( — CH, — ) can become the CH,-group of thymine in
the thymidylic acid synthesis. The same folinic acid (or the corresponding
methenyl [ = CH — ] derivative can form the C,-atom of the future purine ring. The
N10 ...
Joseph Stanley Mitchell, 1965
§Thymidine is the deoxy- form. The ribo- form, ribosylthymine, is not generally
found in nucleic acids. 'Uridine is the ribo- form. Deoxyuridine is not commonly
found, although deoxyuridylic acid is on the pathway for synthesis of thymidylic
acid ...
8
Metabolic Inhibitors V1: A Comprehensive Treatise
The product of this reaction is thymidylic acid which can then be degraded to
thymidine by a phosphatase. This thymidine can be reconverted to thymidylic
acid by a new enzyme. If one supplies an external source of thymidine to the cell,
it is ...
9
Recombinant DNA And Cell Proliferation
REGULATION OF DHF R, TS, AND TK ENZYME LEVELS IN NORMAL CELLS
Thymidylic acid (TMP) is synthesized by two different biochemical pathways, as
shown in Fig. 1. In the de novo synthesis pathway, deoxyuridylic acid (dUMP) is ...
10
INTERNATIONAL REVIEW OF CYTOLOGY
Numerous precursors of DNA (thymidine, thymidylic acid, deoxyuridine,
deoxycytidine, and 5-methyl-deoxycytidine) reverse the effects of the two
inhibitors if they are applied to the bud before or at the same time as the inhibitor.
It may be ...
Geoffrey H. Bourne, James Frederic Danielli, 1967
