ஆங்கிலம் வினைச்சொல் PARP இன் இணைப்பு
PRESENT
Present
I parp
you parp
he/she/it parps
we parp
you parp
they parp
Present continuous
I am parping
you are parping
he/she/it is parping
we are parping
you are parping
they are parping
Present perfect
I have parped
you have parped
he/she/it has parped
we have parped
you have parped
they have parped
Present perfect continuous
I have been parping
you have been parping
he/she/it has been parping
we have been parping
you have been parping
they have been parping
PAST
Past
I parped
you parped
he/she/it parped
we parped
you parped
they parped
Past continuous
I was parping
you were parping
he/she/it was parping
we were parping
you were parping
they were parping
Past perfect
I had parped
you had parped
he/she/it had parped
we had parped
you had parped
they had parped
Past perfect continuous
I had been parping
you had been parping
he/she/it had been parping
we had been parping
you had been parping
they had been parping
FUTURE
Future
I will parp
you will parp
he/she/it will parp
we will parp
you will parp
they will parp
Future continuous
I will be parping
you will be parping
he/she/it will be parping
we will be parping
you will be parping
they will be parping
Future perfect
I will have parped
you will have parped
he/she/it will have parped
we will have parped
you will have parped
they will have parped
Future perfect continuous
I will have been parping
you will have been parping
he/she/it will have been parping
we will have been parping
you will have been parping
they will have been parping
CONDITIONAL
Conditional
I would parp
you would parp
he/she/it would parp
we would parp
you would parp
they would parp
Conditional continuous
I would be parping
you would be parping
he/she/it would be parping
we would be parping
you would be parping
they would be parping
Conditional perfect
I would have parp
you would have parp
he/she/it would have parp
we would have parp
you would have parp
they would have parp
Conditional perfect continuous
I would have been parping
you would have been parping
he/she/it would have been parping
we would have been parping
you would have been parping
they would have been parping
IMPERATIVE
Imperative
you parp
we let´s parp
you parp
NONFINITE VERB FORMS
Present Participle
parping
«PARP» தொடர்புடைய ஆங்கிலம் புத்தகங்கள்
பின்வரும் புத்தக விவரத்தொகுப்புத் தேர்ந்தெடுப்பில்
parp இன் பயன்பாட்டைக் கண்டறியுங்கள்.
parp தொடர்பான புத்தகங்கள் மற்றும் ஆங்கிலம் இலக்கியத்தில் அதன் பயன்பாட்டுச் சூழலை வழங்குவதற்கு அதிலிருந்து பெறப்பட்ட சுருக்கமான சாரங்களைத் தொடர்புபடுத்துகின்றன.
1
PARP as a Therapeutic Target
PARP as a Therapeutic Target provides a comprehensive understanding of how PARP works to aid in the better design of its inhibitors for therapeutic purposes.
derived from PARP-1 deficient mice.2'3 This chapter summarizes the data
obtained from molecular and genetic approaches developed in our laboratory to
better understand the structure-function relationship of the mouse PARP-2.
3
New Developments in Stem Cell Research
With exposure to a high concentration of /V-methyl-iV-nitro-N- nitrosoguanidine (
MNNG). cell death was altered in Parp-1" as compared with Parp-P+ ES cells, but
apoptosis was evident after 24 hrs. These results suggest that Parp-1 is ...
4
New Research on DNA Repair
Mean fold-increase + S.E. in expression of PARP or Pms2 after treatment. *
indicates p< 0.05 [using the paired t-test (one-tailed distribution)], i. e. a
significant increase in expression of PARP or Pms2 in the treated cells compared
to the ...
5
Cell Death: The Role of
PARP
The Role of PARP Csaba Szabo. antagonist group.173,174 The ratio of pro- and
antiapoptotic Bcl proteins is thought to determine the fate of stimulated cells,
death vs. survival.173 The mechanism of action of Bcl-2 involves blocking of the ...
6
Critical Care Nephrology
Poly(ADP)-ribose polymerase (PARP), the most abundant enzyme in the nucleus
, plays an important role in DNA repair, depletion of cellular ATP pools, and
transcriptional control of pro-inflammatory genes.80 PARP is activated by means
of ...
Claudio Ronco, Rinaldo Bellomo, John A. Kellum, 2008
7
Apoptosis, Genomic Integrity, and Cancer
fluorescent antibodies to three critical compounds: Poly(ADP)ribose (PAR),
PARP, and tke cleavage fragment of frARP containing the DMA binding domain (
including lh<? two zinc fingers). The fate of these compounds was followed at two
, ...
Julien L. Van Lancker, 2006
8
Handbook of Neurochemistry and Molecular Neurobiology: ...
... poly(ADP- ribose) polymerase PARP-1 NM_013063 TGATCTGCCTG 0 5 6
MGC5178: hypothetical protein MGC5178; encoded protein has nuclease
domain putatively involved in DNA repair BC000803 Miscellaneous
TAGAGCGTGCT 11 ...
Abel Lajtha, Regino Perez-Polo, Steffen Roßner, 2008
9
Intensive Care Medicine: Annual Update 2008
It has been shown that the PARP inhibitor, BGP-15, ameliorates the renal
damage caused by injection of cisplatin in mice and rats, suggesting that
activation of PARP-1 is implicated in the etiology of cisplatin nephrotoxicity [30].
Burkle et al.
10
Tumor Suppressor Genes
I may be a consequence of PARP-1 depletion, rather than the reduced levels of
p53 transcript [38]. The stable transfection of knockout PARP-1 cells with PARP
cDNA, on the other hand, partially restored p53 expression in PARP-1'/" cells.
Katherine R. Polinsky, 2007
«PARP» வார்த்தையைக் கொண்டுள்ள புதிய உருப்படிகள்
பின்வரும் செய்தி உருப்படிகளின் சூழலில்
parp என்ற வார்த்தையைப் பயன்படுத்துவது பற்றியும் எப்படிப் பயன்படுத்துவது என்பதைப் பற்றியும் தேசிய மற்றும் பன்னாட்டு அச்சகங்கள் என்ன பேசியிருக்கின்றன என்பதைக் கண்டறியுங்கள்.
Fighting womb cancer with PARP inhibitors
In the summer of 2013, mum of two, Suzanne Harford went to see the doctor after noticing unusual changes in her monthly cycle. Thinking that ... «Medical Xpress, ஜூலை 15»
Breast cancer A mouse model for metaplastic breast carcinoma
As BRCA1 deficiency sensitizes tumours to poly(ADP-ribose) polymerase (PARP) inhibitors and most MBCs harbour mutations in BRCA1, Jos ... «Nature.com, ஜூலை 15»
AbbVie's (ABBV) CEO Richard Gonzalez on Q2 2015 Results …
Veliparib is our PARP inhibitor being investigated as a treatment for several solid tumor types. In contrast other PARP inhibitors in development ... «Seeking Alpha, ஜூலை 15»
Active Biotech Stock News -BioMarin Pharmaceutical Inc. (NASDAQ …
The company, on July 20, 2015, declared an update on the ABRAZO Phase 2 study of its poly ADP-ribose polymerase (PARP) inhibitor, ... «Wall Street Observer, ஜூலை 15»
Hitting the self-destruct switch – standing up to womb cancer with …
With support from Stand Up To Cancer, hope is on the horizon in the form of a brand new class of drugs, known as PARP inhibitors. «Cancer Research UK, ஜூலை 15»
That's heaven-scent - clothes that can stop your farts from smelling
UK company Shreddies has been marketing parp-proof pants since 2013, and now they've gone and created jeans and pyjamas for those of us ... «Mirror.co.uk, ஜூலை 15»
Dual Targeted Rx Tested in Breast, Ovarian Cancers
In this study, the PARP inhibitor, olaparib (Lynparza, AstraZeneca), which already has an indication for advanced germline BRCA ... «Clinical Oncology News, ஜூலை 15»
MD Anderson Researchers Identify Mutations in ARID1a Gene That …
“Our results showed, particularly in the ARID1a deficient cells, PARP inhibitors are more effective than in other cancer cells,” said in a news ... «BioNews Texas, ஜூலை 15»
BioMarin provides programme update for talazoparib in metastatic …
BioMarin has provided an update on the ABRAZO Phase 2 study of its poly ADP-ribose polymerase (PARP) inhibitor, talazoparib for the ... «European Pharmaceutical Review, ஜூலை 15»
The 'LinkedIn' for Cancer
On a hunch, Weiss treated her with an experimental drug called a PARP inhibitor as part of a clinical trial. In earlier studies, PARP inhibitors ... «Newsweek, ஜூலை 15»
இல் உள்ள வார்த்தைகளில் மறைக்கப்பட்டிருக்கும் எல்லாவற்றையும் கண்டறியுங்கள் 
