COREPRESSOR SÖZCÜĞÜ İNGILIZCE DİLİNDE NE ANLAMA GELİR?
ortak tutucu
Moleküler biyoloji alanında, bir çekip veren, genlerin sentezlenmesini engelleyen bir maddedir. Prokaryotlarda korrezyon küçük moleküller iken ökaryotlarda korrezyonlar proteintir. Bir çekirgeççi doğrudan DNA'ya bağlanmaz, bunun yerine represörlere bağlanarak dolaylı olarak gen ifadesini düzenler. Bir çekip baskılayıcı, bir baskılayıcı transkripsiyon faktörüne bağlanarak ve aktive ederek genlerin ekspresyonunu indirgemektedir. Bastırıcı bir gen promotörüne bağlanır ve böylece o genin transkripsiyonunu bloke eder.
İngilizce sözlükte corepressor sözcüğünün tanımı
Korpresörün sözlükte tanımlanması, bir baskılayıcı ile birleştirilen ve aktive eden küçük bir moleküldür.
«COREPRESSOR» İLE İLİŞKİLİ İNGILIZCE KİTAPLAR
corepressor sözcüğünün kullanımını aşağıdaki kaynakça seçkisinde keşfedin.
corepressor ile ilişkili kitaplar ve İngilizce edebiyattaki kullanımı ile ilgili bağlam sağlaması için küçük metinler.
1
Diabetes Mellitus: A Fundamental and Clinical Text
The receptor-coactivator interaction requires AF2 in the active orientation;
receptor-corepressor interactions are masked by AF2 (81). Finally, coactivators
are part of larger protein complexes that possess histone acetylase activity,
whereas ...
Derek LeRoith, Simeon I. Taylor, Jerrold M. Olefsky,
2004
2
Biochemical and Functional Analysis of Transcriptional ...
KEYWORDS. transcription; transcriptional repression; corepressor complexes; chromatin; coregulators; cancer; nuclear receptor corepressor (N-CoR); zinc finger protein 217 (ZNF217); pre-mRNA processing 4 kinase (PRP4K)
Jeffrey J. M. Cowger,
2007
3
Transcriptional Corepressors: Mediators of Eukaryotic Gene ...
LBD. proximal to the COR box, that is divergent in sequence between the
different RAR isoforms (Wong and Pri vaisk y l998c) These results confirm a role
for the LBD helix l. if not the COR box motif per se, in regulating corepressor
recruitment ...
Martin L. Privalsky,
2001
4
Molecular and Physiologic Significance of the Nuclear ...
This work extends our understanding of the molecular mechanism by which NRs repress transcription and provides initial in vivo analyses into how the mechanism of repression translates into physiologic importance.
5
Syndromes of Hormone Resistance on the ...
Paolo Beck-Peccoz. (a) WIld Type (b) Mutant f Corepressor^ I complex J
CorepressorN A Corepressor "N complex J (^ complex J TRE TRE Target gene] (
Corepressor A /' Corepressor complex J \ complex ...
6
Molecular Biology of Steroid and Nuclear Hormone Receptors
These results led to the postulation that the LBD peptide competed with TR for a
regulatory molecule, termed a corepressor, that exists in unfractionated nuclear
extracts and is essential for efficient receptor-mediated gene repression.
Leonard P. Freedman,
1998
7
Steroid Receptors—Advances in Research and Application: 2012 ...
Urology, University of Washington, Seattle, WA, United States. (2011 OCT 26)
University of Wisconsin, Madison: Ligand-dependent corepressor acts as a novel
androgen receptor corepressor, inhibits prostate cancer growth, and is
functionally ...
8
Regulation of Organelle and Cell Compartment Signaling
Ligand binding of NRs induces the TBL1/TBL1 dependent recruitment of the E3
ubiquitin-conjugating enzyme UbcH5 and displaces corepressor molecules like
NCoR and HDAC3 in exchange for coactivator complexes that promote gene ...
Ralph A. Bradshaw, Edward A. Dennis,
2011
9
Comprehensive Toxicology
... SMRT) Corepressor Nuclear receptor-interacting protein 1 (NRIP-1, RIP-140)
Corepressor PPAR Nuclear receptor corepressor-1 (NCOR1), -2 (NCOR2, SMRT
) Corepressor Histone deacetylase-3 (HDAC3) Corepressor Scaffold attachment
...
10
Handbook of Cell Signaling, 2/e
Ligand binding of NRs induces the TBL1/TBL1 dependent recruitment of the E3
ubiquitin-conjugating enzyme UbcH5 and displaces corepressor molecules like
NCoR and HDAC3 in exchange for coactivator complexes that promote gene ...
Ralph A. Bradshaw, Edward A. Dennis,
2009
«COREPRESSOR» TERİMİNİ İÇEREN HABERLER
Ulusal ve uluslararası basında konuşulanları ve
corepressor teriminin aşağıdaki haberlerde hangi bağlamda kullanıldığını keşfedin.
MDM4/HIPK2/p53 cytoplasmic assembly uncovers coordinated …
HIPK2 is a member of nuclear Ser/Thr kinase family originally identified as corepressor for homeodomain transcription factors. It activates ... «Nature.com, May 15»
RUNX1/ETO blocks selectin-mediated adhesion via epigenetic …
... O. TEL-AML1 preleukemic activity requires the DNA binding domain of AML1 and the dimerization and corepressor binding domains of TEL. «Nature.com, Nis 15»
Toward understanding the role of the neuron-specific BAF chromatin …
These miRNAs are known targets of RE1-silencing transcription factor (REST), which acts with a corepressor to repress neuronal genes in ... «Nature.com, Nis 15»
Our Viral Inheritance May Make Us Smarter
This mechanism involves a corepressor called TRIM28. The Lund University team, led by Johan Jakobsson, Ph.D., detailed its work January 6 ... «Genetic Engineering & Biotechnology News, Oca 15»
Preventing "Genomic Parasites" from Causing Age-Related Diseases
“Specifically, Sirt6 binds to the 5′-UTR of L1 loci, where it mono-ADP ribosylates the nuclear corepressor protein, KAP1, and facilitates KAP1 ... «Genetic Engineering & Biotechnology News, Eyl 14»
BCM Research Reveals Gene Knockdown Affects Aggression in …
Researchers did a similar knockdown of Atrophin which is a corepressor of tailless. They discovered that the fruit flies were also aggressive. «BioNews Texas, Şub 14»
Rockefeller University's C. David Allis Wins Japan Prize
... researcher Stuart Schreiber and colleagues published a study showing the first known histone deacetylase was a transcription corepressor, ... «Genetic Engineering News, Oca 14»
Oncofetal Gene May Be Marker for Aggressive Liver Cancer
In xenograft models in vivo, blocking SALL4–corepressor interactions released suppression of the phosphatase and tensin homolog protein ... «Medscape, Haz 13»
Scientists engineer 'super mice'
The researchers reduced the expression of a nuclear receptor corepressor (NCoR1) in the muscles tissue, which lead to increased muscle ... «ZME Science, Kas 11»
Gene tweak turns regular mouse into Mighty Mouse
The therapy works by knocking out the gene that makes a protein called nuclear receptor corepressor 1, or NCoR1, which is present in the ... «Mother Nature Network, Kas 11»