PARACRINE SÖZCÜĞÜ İNGILIZCE DİLİNDE NE ANLAMA GELİR?
Parakrin sinyali
Parakrin sinyalizasyon, bir hücrenin yakındaki hücrelerde değişiklikler meydana getirmek için bir sinyal ürettiği, bu hücrelerin davranışını veya farklılaşmasını değiştiren bir hücre-hücre iletişim biçimidir. Parakrin faktörler olarak bilinen sinyal molekülleri, endokrin faktörler ve juxtakrin etkileşimlerinin aksine nispeten kısa mesafelerde yayılır. Parakrin faktörler üreten hücreler onları hücre dışı çevreye salgılarlar. Faktörler, alınan faktörün gradyanının sonucu belirlediği yakındaki hücrelere gider. Bununla birlikte, parakrin faktörlerin nereye kadar gidebileceği kesin değildir. Sinyal transdüksiyon yolaklarına genel bakış. Parakrin sinyalleme, indüklenen hücrelerde çeşitli tepkiler dizisi oluştursa da, parakrin faktörlerin çoğunda nispeten aerodinamik bir dizi reseptör ve yol kullanılır. Aslında, vücudun farklı organları - hatta farklı türler arasında - farklı gelişimde parakrin faktörlerin benzer kümelerini kullandığı bilinmektedir. Oldukça korunan reseptörler ve yolaklar, benzer yapılara dayalı dört ana aileye organize edilebilir: Fibroblast büyüme faktörü ailesi, Hedgehog ailesi, Wnt ailesi ve TGF-β süper ailesi.
İngilizce sözlükte paracrine sözcüğünün tanımı
Sözlükteki parakrin tanımı, salgılanması yalnızca salgılayan salgı bezi çevresindeki dokuyu etkileyen bir hormona ilişkindir.
«PARACRINE» İLE İLİŞKİLİ İNGILIZCE KİTAPLAR
paracrine sözcüğünün kullanımını aşağıdaki kaynakça seçkisinde keşfedin.
paracrine ile ilişkili kitaplar ve İngilizce edebiyattaki kullanımı ile ilgili bağlam sağlaması için küçük metinler.
1
Tumor-stromal Interactions Mediated by
Paracrine Hedgehog ...
SHH paracrine signaling enhances tumor formation in vivo 85 Tumor-associated
stromal cells express a primary cilium 86 SHH paracrine signaling in human
pancreatic fibroblasts 95 Treatment with a neutralizing antibody to SHH (SE1) ...
Jennifer M. Bailey Lundberg,
2009
2
The Role of ATP Release and Autocrine/
paracrine P1/P2 ...
While there is extensive evidence for autocrine/paracrine ATP signaling in many
different cell types (table 2), the actual mechanism for ATP release remains ill
defined. Early studies suggested that the cystic fibrosis transmembrane regulator
...
3
Review of Veterinary Physiology
These neurotransmitters may be released into blood to act as endocrine agents (
neurocrine or neuroendocrine action), or they may be released to act directly on
a target cells in a paracrine fashion (e.g., another nerve, muscle, or endocrine ...
4
Paracrine Regulation of Mammary Ductal Morphogenesis by ...
Our experiments indicate that RAR signaling in adipocytes can regulate the expression of a transmembrane protein, parathyroid hormone receptor (PTHR), and the secreted protein Pleiotrophin (PTN).
Christine V. Marzan,
2008
5
Apoptosis and Inflammation
Deletion can occur as either autocrine (suicide) including AICD, or paracrine (
murder) responses [75]. It is important to note that anergy and apoptosis can be
distinct outcomes of partial activation, and anergy is not simply a prelude to apop-
...
These results suggest that autocrine and/or paracrine signalling by VEGF may
play a role in the pathology of osteoarthritis. VEGF in Hematopoietic Cells and
Hematological Malignancies VEGF plays a central role in hematopoiesis.9 VEGF
is ...
7
Endocrinology: Basic and Clinical Principles
Similarly, growth factors have traditionally been considered as tissue factors,
functioning locally as autocrine or paracrine factors, as compared to hormones
that function in a classic endocrine fashion. We focus here on insulin-like growth
...
Shlomo Melmed, Michael Conn,
2007
8
Stromal-epithelial Hedgehog Signaling in Prostate Cancer
Shh stimulates growth and androgen-independence of tumors, and clinical inhibitors of this pathway should be sure to evaluate the paracrine signaling pathway.
9
Remington: The Science and Practice of Pharmacy
It is regulated by adjacent endocrine, paracrine, and neurocrine cells. The
parietal cell has receptors for acetylcholine (neurocrine), gastrin (endocrine),
histamine (paracrine), somatostatin (endocrine), and prostaglandin E2 (paracrine
).
David B. Troy, Paul Beringer,
2006
10
Endometriosis in Clinical Practice
Thus the modes of action of E and P are complex, cell-type specific, and
dependent on multiple endocrine, paracrine, and autocrine factors. GROWTH
FACTORS AND CYTOKINES The first two growth factors to be discovered were
epidermal ...
«PARACRINE» TERİMİNİ İÇEREN HABERLER
Ulusal ve uluslararası basında konuşulanları ve
paracrine teriminin aşağıdaki haberlerde hangi bağlamda kullanıldığını keşfedin.
Human adipose-derived mesenchymal stem cells attenuate …
In vitro, ASCs inhibit the proliferation of activated lymphocytes via cell-cell binding and paracrine signaling [15]. Expanded ASCs have ... «BMC Blogs Network, Tem 15»
Researchers Identify Potential New Targets for Treating Kidney …
The article, entitled “Paracrine Wnt1 Drives Interstitial Fibrosis without Inflammation by Tubulointerstitial Cross-Talk,” will appear online at ... «Newswise, Tem 15»
iPSCs Show Promise for Kidney Treatment
Second, fibrosis is a marker of progression to chronic kidney disease, suggesting that the paracrine effects could act as preventative therapy for ... «Scicasts, Tem 15»
Induced pluripotent stem cells show promise for kidney treatment
Second, fibrosis is a marker of progression to chronic kidney disease, suggesting that the paracrine effects could act as preventative therapy for ... «Medical Xpress, Tem 15»
Targeting hedgehog signaling reduces self-renewal in embryonal …
... minor inverse-paracrine contribution from the stroma within xenografts (Supplementary Figures 6k and n). Therefore, ligand-based hedgehog ... «Nature.com, Tem 15»
Analysis of the TGFβ-induced program in primary airway epithelial …
The most rapidly inducible, “early” genes were a group encoding cytokines, important in paracrine signaling, whereas late genes were those ... «BMC Blogs Network, Tem 15»
Clinicopathologic analysis of programmed cell death-1 and …
... vivo, various immune and tumor cells produce cytokines that upregulate PD-L1 (CD274) extrinsically in a paracrine and/or autocrine manner. «Nature.com, Tem 15»
Scientific Study Demonstrates That MiMedx Allografts Stimulate …
... shown in previously published peer-reviewed scientific studies to stimulate paracrine responses in cells involved in healing and tissue repair, ... «MarketWatch, Tem 15»
Canine mammary cancer cells direct macrophages toward an …
... to the native receptor (data not shown), indicating that it must depend on either autocrine or paracrine signalling to support cancer expansion. «BMC Blogs Network, Tem 15»
Gene Variant May Affect Postnatal Growth
This therapy may not fully substitute for the auto- and paracrine function of the growth factor, he noted, but "follow-up of our patients shows there ... «MedPage Today, Tem 15»