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在"英语"词典里azathioprine}的意思

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词典
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单词 AZATHIOPRINE的词源

From aza- + thio- + p(u)rine.
info
语源学是对单词起源和它们的结构和意义变化的研究
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英语中AZATHIOPRINE的发音

azathioprine  [ˌæzəˈθaɪəˌpriːn] play
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AZATHIOPRINE的语法类别

noun
形容词
动词
副词
代词
介词
连词
限定词
感叹词

AZATHIOPRINE在英语中的意思是什么?

点击查看«azathioprine»在英语词典里的原始定义
点击查看在中文词典里此定义的自动翻译

硫唑嘌呤

Azathioprine

硫唑嘌呤是用于器官移植和自身免疫疾病的免疫抑制药物,属于嘌呤类似物的化学类别。 1957年最初作为癌症药物和巯嘌呤的前药合成,已被广泛用作50多年的免疫抑制剂。 硫唑嘌呤作为巯基嘌呤的前药,抑制DNA合成所需的酶。 因此,它最强烈地影响增殖细胞,例如免疫系统的T细胞和B细胞。 硫唑嘌呤的主要不利影响是骨髓抑制,这可能是危及生命的,特别是在硫代嘌呤S-甲基转移酶基因缺乏的人群中。 它也被国际癌症研究机构列为第1类致癌物。 硫唑嘌呤由不同品牌的多家制造商生产。 在世界卫生组织的基本药物清单中,列出了基本卫生系统所需的最重要的药物。 Azathioprine is an immunosuppressive drug used in organ transplantation and autoimmune diseases and belongs to the chemical class of purine analogues. Synthesized originally as a cancer drug and a prodrug for mercaptopurine in 1957, it has been widely used as an immunosuppressant for more than 50 years. Azathioprine acts as a prodrug for mercaptopurine, inhibiting an enzyme that is required for the synthesis of DNA. Thus it most strongly affects proliferating cells, such as the T cells and B cells of the immune system. The main adverse effect of azathioprine is bone marrow suppression, which can be life-threatening, especially in people with a genetic deficiency of the enzyme thiopurine S-methyltransferase. It is also listed by the International Agency for Research on Cancer as a Group 1 carcinogen. Azathioprine is produced by a number of manufacturers under different brand names. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

在英语 词典里azathioprine的定义

字典中硫唑嘌呤的定义是抑制机体正常免疫反应的合成药物,并且在器官移植过程中和之后以及在某些类型的自身免疫性疾病中口服给药。 分子式:C 9 H 7 N 7 O 2 S.

The definition of azathioprine in the dictionary is a synthetic drug that suppresses the normal immune responses of the body and is administered orally during and after organ transplantation and also in certain types of autoimmune disease. Formula: C9H7N7O2S.

点击查看«azathioprine»在英语词典里的原始定义
点击查看在中文词典里此定义的自动翻译

AZATHIOPRINE押韵的英语 单词


Adiprene
ˈædɪpriːn
chloroprene
ˈklɔːrəʊˌpriːn
evergreen
ˈɛvəˌɡriːn
figurine
ˌfɪɡəˈriːn
green
ɡriːn
Greene
ɡriːn
isoprene
ˈaɪsəʊˌpriːn
isoxsuprine
aɪˈsɒksəˌpriːn
marine
məˈriːn
neoprene
ˈniːəʊˌpriːn
on-screen
ˌɒnˈskriːn
outpreen
ˌaʊtˈpriːn
polychloroprene
ˌpɒlɪˈklɔːrəʊˌpriːn
polyisoprene
ˌpɒlɪˈaɪsəˌpriːn
preen
priːn
screen
skriːn
submarine
ˈsʌbməˌriːn
vitrine
ˈvɪtriːn
widescreen
ˈwaɪdˌskriːn
wolverine
ˈwʊlvəˌriːn

AZATHIOPRINE一样开头的英语单词

az
az.
azalea
azan
Azania
Azanian
AZAPO
Azazel
Azbine
azedarach
azeotrope
azeotropic
azeotropy
Azerbaijan
Azerbaijani
Azeri
AZERTY
azerty keyboard
azide
azido

AZATHIOPRINE一样开头的英语单词

aquamarine
brine
caprine
Catherine
chlorine
cyprine
doctrine
endocrine
exocrine
Katharine
Katherine
margarine
murine
poitrine
serine
shrine
tangerine
trine
urine
uterine

英语近义词词典里azathioprine的近义词和反义词

近义词

«azathioprine»的25种语言翻译

翻译者
online translator

AZATHIOPRINE的翻译

通过我们的英语多语言翻译器,找到azathioprine25种语言翻译
该章节所呈现的将azathioprine由 英语向其他语言的翻译是通过自动统计翻译获得的;在英语中基本的翻译单位是单词«azathioprine»。

翻译者英语 - 中文

硫唑嘌呤
1,325 数百万发言者

翻译者英语 - 西班牙语

azatioprina
570 数百万发言者

英语

azathioprine
510 数百万发言者

翻译者英语 - 印地语

azathioprine
380 数百万发言者
ar

翻译者英语 - 阿拉伯语

الآزوثيوبرين
280 数百万发言者

翻译者英语 - 俄语

азатиоприн
278 数百万发言者

翻译者英语 - 葡萄牙语

azatioprina
270 数百万发言者

翻译者英语 - 孟加拉语

azathioprine
260 数百万发言者

翻译者英语 - 法语

azathioprine
220 数百万发言者

翻译者英语 - 马来语

Azathioprine
190 数百万发言者

翻译者英语 - 德语

Azathioprin
180 数百万发言者

翻译者英语 - 日语

アザチオプリン
130 数百万发言者

翻译者英语 - 韩语

아자 티오 프린
85 数百万发言者

翻译者英语 - 印尼爪哇语

Azathioprine
85 数百万发言者
vi

翻译者英语 - 越南语

azathioprine
80 数百万发言者

翻译者英语 - 泰米尔语

அசாதியோப்ரின்
75 数百万发言者

翻译者英语 - 马拉地语

अझॅथीओप्रिन
75 数百万发言者

翻译者英语 - 土耳其语

azatioprin
70 数百万发言者

翻译者英语 - 意大利语

azatioprina
65 数百万发言者

翻译者英语 - 波兰语

azatiopryna
50 数百万发言者

翻译者英语 - 乌克兰语

азатіоприн
40 数百万发言者

翻译者英语 - 罗马尼亚语

azatioprina
30 数百万发言者
el

翻译者英语 - 希腊语

αζαθειοπρίνη
15 数百万发言者
af

翻译者英语 - 布尔语(南非荷兰语)

azathioprine
14 数百万发言者
sv

翻译者英语 - 瑞典语

azatioprin
10 数百万发言者
no

翻译者英语 - 挪威语

azatioprin
5 数百万发言者

azathioprine的使用趋势

趋势

词语 «AZATHIOPRINE»的使用趋势

0
100%
频率
经常使用
64
/100
此处所显示的地图给出了词语«azathioprine»在不同国家的使用频率。
azathioprine的主要搜索趋势和常见用法
用户为查找我们的英语在线词典以及单词«azathioprine»的最常用表达而进行的主要搜索的列表。

词语«AZATHIOPRINE» 随时间而变化的使用频率

该图表展现了单词«azathioprine»在过去500年中的用法频率的每年演化其实施是基于分析词语«azathioprine»从1500年到现在在 英语数字出版物中出现的频率。

azathioprine的英语文献、引用和新闻中的使用范例

示例

«AZATHIOPRINE»相关的英语书籍

在以下的参考文献中发现azathioprine的用法。与azathioprine相关的书籍以及同一来源的简短摘要提供其在 英语文献中的使用情境。
1
Current Therapy in Neurologic Disease
Because the beneficial effects of azathioprine may take more than 6 months to appear, the combination of azathioprine and steroids or azathioprine and IVIg affords the relatively rapid onset of immunosuppression produced by the steroids or ...
Richard Tidball Johnson, John W. Griffin, Justin C. McArthur, 2006
2
Drugs in Pregnancy and Lactation: A Reference Guide to Fetal ...
Intrauterine growth restriction also has been reported, but this effect may have been a consequence of multiple factors, one of which was azathioprine, working in combination. Taken in sum, however, the evidence suggests that the maternal  ...
Gerald G. Briggs, Roger K. Freeman, Sumner J. Yaffe, 2011
3
Chemical Stability of Pharmaceuticals: A Handbook for ...
4. cx>. C9H7N702S mol. wt . 277.3 Forms Available Free acid ( az a t h 1 o pr i ne ) ; sodium a z a t h i op r i ne , Na( C9H6N702S) . Physical Properties Azathioprine melts at approximately 240°C (1). Solubility: 0.130 mg/mL in water at 25°C (2) ...
Kenneth Antonio Connors, 1986
4
Pediatric Gastrointestinal Disease: Pathophysiology, ...
or colonic resection.162 Another study suggested that aza- thioprine heals recurrent ileitis developing in the neoter- minal ileum.163 Azathioprine also has been widely used in the therapy of inflammatory bowel disease. The results suggest ...
W. Allan Walker, 2004
5
Advanced Therapy of Inflammatory Bowel Disease: Ulcerative ...
CONCLUSION In summary, the immunomodulators 6-MP and azathioprine are some of the best therapies currently available for the treatment of chronic UC. They are usually well tolerated and easy to dose. Unfortunately, many clinicians ...
Theodore M. Bayless, Stephen B. Hanauer, 2011
6
Textbook of Atopic Dermatitis
o Subjects receiving azathioprine 2.5 mg/kg/day (n = 18) followed by placebo (n = 1 1 ) 0 Subjects receiving placebo (n = 17) followed by azathioprine (n = 15) Figure 18.4 Mean SASSAD scores during treatment for 3 months with azathioprine ...
Sakari Reitamo, Thomas A. Luger, Martin Steinhoff, 2008
7
A Manual of Adverse Drug Interactions
In the treatment of psoriatic arthritis there is the clinical belief that azathioprine is more effective for the arthritic element and methotrexate for the dermatological manifestations. In myasthenia gravis where thymectomy is not advisable ...
J.P. Griffin, P.F. D'Arcy, 1997
8
European Drug Index: European Drug Registrations, Fourth Edition
Azathioprinum 50mg (L04AX01) (BG) Azathioprine (Generics) tab.: Azathioprinum 50mg(L04AX01)(BG) Azathioprinetablets 50 mg Azathioprine ( L04AX01)(RUS) Azathioprine 50mg(Medexport V/O Moscow) tab.: Azathioprinum (L04AX01) ...
Muller, 1998
9
Kidney Transplantation - Principles and Practice
Azathioprine and 6-mercaptopurine are thiopurines, and azathioprine is an imidazolyl derivative of 6-mercaptopurine. Azathioprine is metabolized in the liver before becom- ing active. One metabolic pathway is through its con- version to ...
Peter Morris, Stuart J. Knechtle, 2013
10
Concepts in Immunology and Immunotherapeutics
The therapeutic use of azathioprine in renal transplantation. Pharmacotherapy. 1987; 7(5):165–177. 96. Van Scoik KG, Johnson CA, Porter WR. The pharmacology and metabolism of the thiopurine drugs 6-mercaptopurine and azathioprine.
Blaine T. Smith, 2008

包含词语«AZATHIOPRINE»的新条目

找出国内和国际出版社所讨论的内容,以及词语azathioprine在以下新条目的上下文中是如何使用的。
1
Kansas senior's battle with rare disease and how to help. What is …
Immunosuppressant drugs, such as azathioprine and methotrexate, may reduce inflammation in people who do not respond well to prednisone ... «Outbreak News Today, 七月 15»
2
SIMPONI® Receives European Commission Approval for Treatment …
... including corticosteroids and 6-mercaptopurine or azathioprine, or who are intolerant to or have medical contraindications for such therapies. «PharmiWeb.com, 七月 15»
3
Pfizer Announces FDA Acceptance for Review of New Drug …
Use of XELJANZ in combination with biologic DMARDs or potent immunosuppressants, such as azathioprine and cyclosporine is not ... «MarketWatch, 七月 15»
4
Necrotizing Myopathy: Are Statins to Blame?
Treatment of these patients has included prednisone, azathioprine, methotrexate, rituximab, and intravenous immunoglobulin (IVIG). «MedPage Today, 七月 15»
5
Psoriatic Arthritis Pharmacotherapy Market Segment Forecasts up to …
While immunosuppressant helps to control the immune system including azathioprine and cyclosporine. TNF-α inhibitors assist reducing pain, ... «CSO Australia, 七月 15»
6
As PGx Program Grows, Vanderbilt Hoping to Expand Reported …
... at Vanderbilt have TPMT alleles that placed them at risk for responding poorly to thiopurines — drugs such as azathioprine, mercaptopurine, ... «GenomeWeb, 六月 15»
7
mTOR inhibitor versus mycophenolic acid as the primary …
Since mycophenolic acid (MPA) was introduced into solid organ transplantation, it has largely replaced azathioprine (AZA) as the ... «BMC Blogs Network, 六月 15»
8
EU approves Simponi to treat non-radiographic axial spondyloarthritis
... including corticosteroids and 6-mercaptopurine or azathioprine, or who are intolerant to or have medical contraindications for such therapies. «pharmabiz.com, 六月 15»
9
Infections, age and medications linked to death in patients with …
... followed by intravenous glucocorticoids in 64%, cyclophosphamide in 43%, pulse cyclophosphamide in 49% and azathioprine in 25%. «Healio, 六月 15»
10
Early treatment best for rheumatoid arthritis
Commonly prescribed DMARDs include methotrexate, sulfasalazine, penicillamine, leflunomide, azathioprine, cyclosporin and mycophenolate. «Stuff.co.nz, 六月 15»

参考文献
« EDUCALINGO. Azathioprine [在线]. 可用 <https://educalingo.com/zh/dic-en/azathioprine>. 四月 2024 ».
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