与 «CLEAVABILITY»相关的英语书籍
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Amultibasic cleavagesiteisnotthe onlyrequirement forhigh cleavability.Another
important determinantisa carbohydrate sidechain close to the cleavagesite that
interferes with protease accessibility. Lossofthis carbohydrateresulted
inenhanced ...
Robert G. Webster, Arnold S. Monto, Thomas J. Braciale, 2014
A multibasic cleavage site is not the only requirement for high cleavability.
Another important determinant is a carbohydrate side chain close to the cleavage
site that interferes with protease accessibility. Loss of this carbohydrate resulted
in ...
Hans-Dieter Klenk, Mikhail N. Matrosovich, Jürgen Stech, 2008
3
Macromolecular Anticancer Therapeutics
Cleavability. of. Conjugates. Release of the drug from HPMA-based polymeric
backbone was generally agreed to be a prerequisite for efficacy of polymeric
conjugates. Comparison of in vivo efficacy of conjugates with cleavable GFLG
and ...
L. Harivardhan Reddy, Patrick Couvreur, 2010
4
Encyclopedia of General Topology
This yields cleavability of perfectly normal metacompact scattered spaces (in
particular, metrizable scattered spaces). The class of cleavable spaces is not
closed underproducts: the product I ×D(τ) of the closed interval I and the discrete
space ...
K.P. Hart, Jun-iti Nagata, J.E. Vaughan, 2003
Cleavability. — The test for cleavability should be applied by an experienced
workman. The block should be freshly quarried, unfrozen, and moist. The chisel
should be very thin and about 2 inches wide. The cost of slate is closely related to
...
Investigations have shown in certain instances that the cleavability of a rock
varies with its composition." This expresses also the fact that cleavability varies
with mineralogical composition. In the development of flow cleavage in a
noncleavable ...
Charles Kenneth Leith, 1905
7
Modulating Lipsomal Stealth Properties to Evade RES and ...
THIOLYTIC CLEAVABILITY OF DSPE-S-S-PEG The thiolytic cleavability of the
conjugate was confirmed by treating 1 mM mic in PBS for 30 min at 37°C. LC
ellar conjugate with cysteine of 10 mM concentration The degree of cleavage
was ...
Kathleen Margaret McNeeley, 2008
8
Influenza Virus Sialidase - A Drug Discovery Target
Recently, two serine proteases (TMPRSS2 and HAT) from human airway
epithelium have been found to activate human influenza A viruses as well as a
LPAI virus [151]. Bacterial proteases may also activate HAs of restricted
cleavability and ...
9
The Reactive Site Loop Cleavage Motif of Baculovirus P49 ...
In fact, the greatest increase in P49 cleavability by a single amino acid
substitution was the P3 Val to Ala substitution, which increased DRONC
cleavability by ~8-fold (Fig. 3.2C). P49PDTATD substrate was a ~ 10-fold better
DRONC-His6 ...
10
Animal Viruses: Molecular Biology
Loss of this carbohydrate resulted in enhanced HA cleavability and pathogenicity
(Kawaoka et al., 1984). However, masking of the cleavage site by this
oligosaccharide was overcome when the number of basic amino acids was
increased ...
Thomas C. Mettenleiter, Francisco Sobrino, 2008