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1
Abnormal Skeletal Phenotypes: From Simple Signs to Complex ...
Preaxial Polydactyly [Increased number of digits on the radial side of the hand]
Polydactyly is a relatively common congenital defect, with an estimated birth
prevalence rate of about 170 in 100,000 (Castilla et al. 1996). In declining order
of ...
Alessandro Castriota-Scanderbeg, Bruno Dallapiccola, 2006
2
Anatomy: Embryology, Gross Anatomy, Neuroanatomy, Microanatomy
A. Limb rotation: After formation of limb buds, the axis of the limb rotates 90°
medially so the preaxial (flexor) musculature comes to lie posteriorly and
postaxial (extensor) musculature moves anteriorly. B. Innervation pattern: In the
lower limb, ...
Raymond E. Papka, J.J. Tomasek, 1995
3
The Bedside Dysmorphologist
10.1. Preaxial. Polydactyly. Recognizing the Sign Hallucal reduplication is
unlikely to be missed. However, subclinical forms should be suspected in
halluces that are clinically broad, the wide toe perhaps representing an
underlying ...
Crumlin William Reardon Consultant Clinical Geneticist Our Lady's Hospital for Sick Children, Dublin, 2007
Several sets of monozygous twins have been discordant for preaxial polydactyly (
78, 79). The rate of concordance in monozygous twins has not been established.
Genetic Factors The likelihood of inheritance of the preaxial polydactyly varies ...
5
Fundamentals of Hand and Wrist Imaging
Unilateral polydactyly is more common in preaxial than in postaxial polydactyly.
The delta phalanx anomaly (longitudinally bracketed diaphysis) is a distinct
fusion anomaly, characterized by a trapezoid-shaped diaphyseal-metaphyseal
unit, ...
Giuseppe Guglielmi, Cornelis Van Kuijk, Harry K. Genant, 2001
6
Fins into Limbs: Evolution, Development, and Transformation
Each appendage is oriented with anterior (preaxial) upward and distal to the right
. Figures are not to scale. describe the early pectoral fin development of
Polyodon as arising out of a single cartilaginous plate, termed the endochondral
disc.
7
Clinical Anatomy for Students: Problem Solving Approach
In the embryo the upper limb bud carries within it the ventral rami from C5 to Tl
segments of the spinal cord. Each limb bud has ventral and dorsal surfaces and
preaxial (cranial) and postaxial (caudal) borders. The upper limb bud undergoes
...
8
NORD Guide to Rare Disorders
The phenotype is characterized by preaxial and postaxial polydactyly, syndactyly
of fingers and toes, and macrocephaly resulting in apparent hypertelorism.
SYNONYM: Polysyndacryly with peculiar skull shape. DIFFERENTIAL
DIAGNOSIS: ...
National Organization for Rare Disorders, 2003
9
Physical Diagnosis in Neonatology
When a deficiency is preaxial, the association with malformations in other
systems is far greater than in postaxial deficiencies. Radial defects in particular
are strongly associated with other malformations, with reported involvement
ranging up ...
10
In Vitro Methods in Developmental Toxicology: Use in ...
Treatment with BUdR at stages and dosages that produce a high incidence of
preaxial polydactylism prevents expression of PCD in the fpp, but not in the AER.
59 This represents a primary modification, as the regimen did not induce a prior ...
Gary L. Kimmel, Devendra M. Kochhar, 1989
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Surgical strategy for polydactyly of the thumb
Polydactyly of the thumb, radial polydactyly, or preaxial polydactyly is common in all races, and about 20 percent of them occur bilaterally. «BMC Blogs Network, 五月 15»
Which Dog Breeds Have the Most Toes?
The trait is due to a non-sex-linked recessive gene, and is technically called hind-limb-specific preaxial polydactyly. Yeah, we'll call them "rear ... «Dog Channel, 一月 15»
Sexual dimorphism in large-sized, long-snout ichthyosaurs
In most described large-sized long-snout ichthyosaur specimens, the hindfin is relatively thin and long, and with no preaxial accessory digit ... «Phys.Org, 十二月 13»
The problem with polydactylism
The 27- year-old was born with six toes on each foot — an extra toe on the side of each of her big toe and was diagnosed with preaxial ... «Trinidad & Tobago Express, 九月 13»
Coelacanths are unexceptional products of evolution
The three first preaxial radials are numbered from proximal to distal. In L. chalumnae the fin appears nearly symmetrical because radial bones ... «ScienceBlogs, 四月 13»
Highlights of the BMC-series: February 2013
Preaxial polydactyly type I (PPD1), the most common form of polydactyly is typically characterized by the doubling of one or more skeletal ... «BMC Pediatrics, 三月 13»
Epidemiology of isolated preaxial polydactyly type I: Data from the …
Preaxial polydactyly type I (PPD1) is the most frequent form of preaxial polydactyly. The etiology of sporadic PPD1 remains largely unknown ... «BMC Pediatrics, 二月 13»
For Whom the Cell Mutates: The Origins of Genetic Quirks
When found in felines, the condition, formally known as preaxial polydactyly, is now commonly referred to as a “Hemingway cat.” The origins of ... «New York Times, 三月 11»
MSNBC's Birthday Present to Charles Darwin: Puff-Pieces on …
It requires some pesky evolutionary reversals, as the Nature piece states: "If our interpretations are correct, the preaxial pattern of digital ... «Discovery Institute, 二月 09»
Hydrolethalus Syndrome: Neuropathology of 21 Cases Confirmed …
In addition, this fetus had palatoschisis, micrognathia, hypertelorism, broad nose, postaxial polydactyly in hands, and preaxial polydactyly in ... «RedOrbit, 九月 08»
