与 «RACEMATE»相关的英语书籍
在以下的参考文献中发现
racemate的用法。与
racemate相关的书籍以及同一来源的简短摘要提供其在 英语文献中的使用情境。
1
Dictionary of Food Compounds with CD-ROM, Second Edition
Mp 300 (racemate). Exhibits polymorphism. Glycerol 1,2-didecan0ate 3-
tetradecanoate [62833-19-6] T etradecanoic acid 2,3-bis[ (1 -oxodecyl)
oxyjpropyl ester. oi, ß -Dicapromyristin 1,2-Didecanoyl-3-tetradecanoylglycerol [
57416-11-21 ...
2
Pharmacogenetics of Psychotropic Drugs
Escitalopram Enantiomer (S) -Citalopram + + + Citalopram Racemate (S) -
Citalopram + + + Fluoxetine Racemate (S)-and(R)-Fluoxetine + + Paroxetine 3S-
trans- Paroxetine 3S-f rans- Paroxetine + + Sertraline (+)-ds-(15,4S)-Sertraline ...
experimentally determined concentration was found to range between 98 and
104% of the true value with a minimum detection limit of approximately 3% (w/w)
for both the enantiomer and the racemate [35]. 3.4.5 Infrared, Raman, and ...
Kenneth W. Busch, Marianna A. Busch, 2011
4
Chirality in Drug Design and Development
Let us discuss different scenarios that may arise from a racemate consisting of
two enantiomers. In this case, there could be four different scenarios with respect
to the PK and PD of the two enantiomers; same PK and PD (efficacy and toxicity ...
Indra K. Reddy, Reza Mehvar, 2004
5
Dictionary of Food Compounds with CD-ROM: Additives, ...
Glycerol l,2-didodecanoate 3-(9Z-octade- cenoate) [158112-13-1] [20299-66-5,
67254-18-6] l,2-Dilauroyl-3-oleoylglycerol a,fl-Dilaur- oolein C45H84O6 721.155
Oil (ff-form), cryst (Et2O)(racemate). Mp 16° (racemate) Mp 20° (racemate).
6
Drug Discrimination: Applications to Medicinal Chemistry and ...
Due to the added cost, labor, and/or synthetic complexity associated with
resolution or stereoselective synthesis, racemates are commonly prepared and
used for initial pharmacological evaluations. Very often, it is only after a racemate
shows ...
Richard A. Glennon, Richard Young, 2011
7
Chiral Separation Methods for Pharmaceutical and ...
The EU guidance also provided more detail than the U.S. guidance for
nonclinical testing for a single enantiomer vs. a racemate as well as a single
enantiomer from an approved racemate. The guidance also noted nonclinical
considerations ...
8
Smith and Williams' Introduction to the Principles of Drug ...
Examination of both the individual enantiomers and the racemate, in animal
models of depression, have also indicated the twofold potency of (S)-citalopram
in comparison to the racemate and the lack of activity of the R -enantiomer.
H. John Smith, Hywel Williams, 2005
9
Chirality in Industry II: Developments in the Commercial ...
glomerate. If the spectra are different, then it is most likely that the racemate forms
compound crystals (although it is also a possibility that the racemate is a
conglomerate, but in a different polymorph or solvate phase from the pure enan-
tiomer) ...
A. N. Collins, G. N. Sheldrake, J. Crosby, 1997
10
CRC Handbook of Optical Resolutions via Diastereomeric Salt ...
The diastereomeric salts separated as well-developed crystals from ethyl acetate,
but their decomposition produced only the racemate. The crystal structure of the
salt formed from 4.5 was determined by X-ray crystallography. The 1 : 1 salt ...
包含词语«RACEMATE»的新条目
找出国内和国际出版社所讨论的内容，以及词语
racemate在以下新条目的上下文中是如何使用的。
Extending the Range of Laboratory-Scale Purification by Utilising …
In this article the challenges in extending the upper limit of laboratory-scale purification from 50 g to 500 g (racemate) are highlighted and the controls required to ... «Labmate Online, 七月 15»
Structural biology A racemate to the rescue
Mycobacterium tuberculosis, the causative agent of tuberculosis, can enter a dormant state within macrophages that is difficult to eliminate and can subsequently ... «Nature.com, 四月 15»
New Team on Aussie Speedcar Scene
Steve is an avid speedway fan who owns a local West Aussie business, “Racemate Storage Solutions.” The first outing for the new look team will be the WASDA ... «Speedcarworld, 八月 14»
Thalidomide, Bound to Its Target
It doesn't matter if you take the racemate or a pure enantiomer; you're going to get both of the isomers once it's in circulation. The compound's horrific effects led ... «Corante, 七月 14»
Supreme Court upholds escitalopram product claim in view of …
Citalopram is a so-called racemic mixture or racemate of two different enantiomers, a (+) and a (-) enantiomer (also referred to as S- and R-enantiomers). «Lexology, 一月 14»
Plavix patent: Federal Court of Appeal reverses inutility and …
An earlier patent ('875) encompassed clopidogrel bisulfate within its claims and included an example describing the racemate. The claims also referred to ... «International Law Office, 九月 13»
Pharma in brief - Canada: Federal Court of Appeal overturns …
Clopidogrel bisulfate is the dextro-rotatory isomer (enantiomer) of a racemate (a mix of two mirror image enantiomers, the dextro- and the levo- rotatory isomers). «Lexology, 八月 13»
Federal Court of Appeal finds Sanofi's Plavix patent valid and infringed
It relates to the active and less toxic enantiomer of a racemate2 known as PCR 4099 which falls within a large genus of racemates claimed in Sanofi's Canadian ... «Lexology, 八月 13»
Levomilnacipran: A Brief Overview
Like its racemate, levomilnacipran is neither a substrate for nor potent inhibitor of cytochrome P450 isoenzymes. Because levomilnacipran is primarily excreted ... «Medscape, 七月 13»
Federal Court upholds Lundbeck's escitalopram patent
The court dismissed this ground as it disagreed with Apotex that the patent promised that escitalopram had greater therapeutic effect than the racemate. «International Law Office, 四月 13»
