与 «SENESCENT»相关的英语书籍
在以下的参考文献中发现
senescent的用法。与
senescent相关的书籍以及同一来源的简短摘要提供其在 英语文献中的使用情境。
1
Age Rage and Going Gently: Stories of the
Senescent Subject ...
It espouses a critical interdisciplinarity and calls into question the assumptions underlying much research into ageing in the social sciences, work in which the negative aspects of growing older are almost invariably suppressed.
2
Anxiety and Preoperative Education in the
Senescent Patient
This study will focus on preoperative education for the senescent adult as it
relates to anxiety before and after the education process to determine the extent
to which providing this education will alter anxiety in this population. Simply
stated ...
3
Principles and Practice of Geriatric Surgery
In fact, a persistent DDR and elevated intracellular ROS production appear to
play a critical role not only in the induction of the senescent phenotype but also in
its maintenance [279, 281]. Products of the retinoblastoma (Rb) and p53 tumor ...
Ronnie Ann Rosenthal, Michael E. Zenilman, Mark R. Katlic,
2011
The concept of senescent alopecia evolved from clinical observations that diffuse
hair thinning involving the whole scalp may develop after the age of 50 years in
people with no family history of balding. Scalp surface studies favored the idea ...
Ralph M. Trüeb, Desmond Tobin,
2010
5
Aging and Age-related Diseases: The Basics
It is difficult to know the extent to which the senescent states are induced by the
ep53 and pRB pathways are distinct or similar. In addition, depending on the
tissue and species of origin, cells may differ in both their senescent phenotype
and ...
pathways identified in cellular senescence involve p53, p16, p21 and pRB [70].
There is compelling evidence suggesting that senescent cells accumulate in
aged tissues [71–73]. In order to assess the contribution of senescent cells to
aging ...
Miranda A. Farage, Kenneth W. Miller, Howard I. Maibach,
2010
7
Cells, Aging, and Human Disease
This is more difficult than counting population doublings, though also more
rewarding experimentally, theoretically, and clinically. Orthogonally to the
problem of measuring senescence is the problem of agreeing to a cutoff: how
senescent is ...
Michael B. Fossel M.D. Clinical Professor of Medicine Michigan State University,
2004
8
Biological Aging: Methods and Protocols
accumulation of senescent cells in aged tissues is also thought to contribute to
age-related pathologies (3). It is generally accepted that human fibroblasts and
other cell types senesce after repeated cell division because they eventually ...
Trygve O. Tollefsbol,
2007
9
Tumor Dormancy, Quiescence, and Senescence, Volume 1: Aging, ...
Senescent cells can affect their microenvironment in multiple ways. The influence
of SASP components is not restricted to the ECM or to cells in their immediate
microenvironment. Several of these components are potent proinflammatory ...
10
New Research on Cell Aging
Cells that demonstrated apoptosis after nocodazole treatment, however, greatly
decreased in later passages suggesting dysfunction of mitotic checkpoint in
senescent cells. The observations in this study suggest that the mitotic failure
caused ...
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Cell signalling Limiting the side effects of senescence
The SASP is a major feature of senescent cells and involves the secretion of cytokines, growth factors and proteases. Cellular senescence, which is a state of ... «Nature.com, 七月 15»
Post-Senescent Stage of Advanced Capitalism; EU and Greece
One mark of the post-senescent stage of advanced capitalism is that traditional imperialist concerns of markets, investments, raw materials ownership and ... «CounterPunch, 七月 15»
Protein in metabolic reprogramming restrains senescent cells from …
Shown on the left is an ATM positive cell that has undergone senescence (depicted by blue color). On the right are cells with low ATM that are not senescent due ... «Medical Xpress, 四月 15»
Cell senescence Communicating with senescence
Senescent cells secrete molecules to communicate with surrounding cells. Biran et al. report that communication can also occur by intercellular protein transfer ... «Nature.com, 四月 15»
SIWA's Approach To Clearing Senescent Cells To Increase …
The results of the work performed by Charles River for SIWA include an increase in gastrocnemius muscle mass and reduction of a senescent cell mRNA marker ... «PR Web, 三月 15»
New range of drugs may slow ageing process by taking out …
Their research focuses on so-called senescent cells - cells we acquire throughout life that shut down, stop dividing and sit there making few useful contributions ... «South China Morning Post, 三月 15»
A True Fountain-Of-Youth Drug Combo?
Most of them do, but some cells become senescent: old geezers who just won't go away. The problem is, these cells just don't sit quietly in the living room ... «Forbes, 三月 15»
Kill Senescent Cells Before They Kill You
Researchers searched for ways to eliminate cells in the body that have become senescent and destructive. Their tests in cell cultures and in genetically-modified ... «ScienceBlog.com, 三月 15»
New class of drugs reduces aging in mice, Mayo Clinic study finds
The study found two drugs that were especially good at getting rid of senescent cells. These are cells that have ceased to reproduce through division but also ... «Washington Post, 三月 15»
Senescent cells play an essential role in wound healing
Senescent cells have a bad-guy reputation when it comes to aging. While cellular senescence - a process whereby cells permanently lose the ability to divide ... «EurekAlert, 十二月 14»