10 ENGLISH BOOKS RELATING TO «CALPAIN»
Discover the use of
calpain in the following bibliographical selection. Books relating to
calpain and brief extracts from same to provide context of its use in English literature.
1
Regulation of
Calpain-1 Signaling in Platelets
There has been considerable interest in elucidating the physiological function of calpains implicating them in a wide variety of cellular processes including cell motility, proliferation, apoptosis, cytoskeleton rearrangement, and ...
2
Calpain Methods and Protocols
annot be homogenized immediately, store tissue at -70°C to minimize m calpain
activation. Do not freeze sample in liquid nitrogen as this e sample and reduce
calpain activity. d brain samples, large amounts of protein (100-150 Jig) may be ...
3
Calpains: Pharmacology and Toxicology of a Cellular Protease
This new edition offers a clear and through examination of the most recent results of thirty years of research on calcium-activated-neutral protease (CANP or Calpain).
K K W Wang, Po-wai Yuen, 1999
4
Encyclopedia of Molecular Pharmacology
Calpains. Figure 1 Domain structures of calpain superfamily. Figure kindly
provided by Dr. Hiroyuki Sorimachi, Laboratory of Biological Function, University
of Tokyo, Japan. Examples of pathological conditions that have been associated
to the.
5
Handbook of Neurochemistry and Molecular Neurobiology: ...
An increase in the intracellular free Ca2+ level activates the Ca2+-dependent
cysteine protease calpain that can mediate neuronal death. Various studies
demonstrated that calpain could degrade key cellular substrates so as to impair ...
Abel Lajtha, Naren Banik, 2007
6
Cardiac Arrest: The Science and Practice of Resuscitation ...
calpain and m-calpain undergo N-terminal autoproteoly- sis at a [Ca2] slightly
greater than that required for substrate proteolysis. The result of autoproteolysis
is a decreased Ca2 requirement for subsequent proteolytic activity (0.6–0.8 M for
...
Norman A. Paradis, Henry R. Halperin, Karl B. Kern, 2007
In most reported cases, down-regulation is inhibited by calpain inhibitors
although this effect is not always seen2 '3 and inhibition is at best partial. The mM
calpain isoform (m-calpain) has been shown to cleave PKC more efficiently than
the ...
8
Protein Misfolding, Aggregation and Conformational Diseases: ...
Calpains, a class of Ca2-dependent cysteine proteases, were the obvious
candidates for that role. Skeletal muscles contain the ubiquitous m-calpain and -
calpain (activated at mM and M Ca2 concentration, respectively) and a muscle
specific ...
Vladimir N. Uversky, Anthony Fink, 2007
9
Indicators of Milk and Beef Quality
muscle fibres with μ-calpain resulted in thinner Z-lines and reduced fibre strength
, demonstrating that μ-calpain is capable of reducing the mechanical strength of
muscle fibres (Christensen et al., 2003). Recently a role of calpain 3 (i.e. p94) ...
J. F. Hocquette, S. Gigli, 2005
10
Comprehensive Toxicology
Multiple members of the caspase family have been shown to be cleaved directly
by calpain leading to their inactivation (Chua et al. 2000), suggesting an
important antiapoptotic role for calpain in the modulation and regulation of known
...
10 NEWS ITEMS WHICH INCLUDE THE TERM «CALPAIN»
Find out what the national and international press are talking about and how the term
calpain is used in the context of the following news items.
Hypoxia induces calpain activity and degrades SMAD2 to attenuate …
Under inflammatory conditions or during tumor progression macrophages acquire distinct phenotypes, with factors of the microenvironment ... «7thSpace Interactive, Jul 15»
The flavonoid beverage Haelan 951 induces growth arrest and …
A major challenge in pancreatic cancer treatment is the resistance of human pancreatic cancer cells to apoptosis. Soy isoflavones and calpain ... «7thSpace Interactive, Jul 15»
Genetic evidence in the mouse solidifies the calcium hypothesis of …
Calcium overload also promotes activation of the calcium-activated protease calpain, which has also been shown to contribute to the ... «Nature.com, Jun 15»
Perfect the art of smoking meat with the help of science
Just below 40 degrees is where an enzyme called calpain reaches peak productivity, while another called cathepsin produces the best results ... «Techly, Jun 15»
Tandem phosphorylation within an intrinsically disordered region …
Cleavage of ACTN4 by m-calpain, a protease that in motile cells is predominantly activated at the rear, removes the Tyr4 site. We found that introducing a ... «Science Magazine, May 15»
Authors Lien CY, Chuang TY, Hsu CH, Lin CL, Wang SE, Sheu SJ …
... Bcl-2-associated X protein, calpain, caspase 12, caspase 9, and caspase 3 were significantly suppressed in DOX-treated mice under oral ... «Dove Medical Press, May 15»
Early Passion for Science, Medicine Puts UK Grad on Fast Track to …
He worked with particular isoforms calpain 5 and 7, atypical calpains whose role in the nervous system are poorly understood. His projects ... «UKNow, May 15»
Gephyrin: a central GABAergic synapse organizer
Gephyrin was found to interact directly with and be subject to proteolysis by the Ca2+-dependent cysteine protease, calpain-1, suggesting that ... «Nature.com, Apr 15»
Consortium of LGMD Foundations Expands Free Diagnostic …
The consortium includes the Cecil B Day Family, Inc (LGMD2B), Coalition to Cure Calpain 3 (LGMD2A), Jain Foundation (LGMD2B), Kurt + ... «Business Wire, Mar 15»
Intracellular Calcium Affects Colon Cancer Cell Motility
... study “Modulation of Intracellular Calcium Levels by Calcium Lactate Affects Colon Cancer Cell Motility through Calcium-Dependent Calpain ... «Colon Cancer News Today, Feb 15»
