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WHAT DOES METABOTROPIC RECEPTOR MEAN IN ENGLISH?
A metabotropic receptor is a type of membrane receptor of eukaryotic cells that acts through a secondary messenger. It may be located at the surface of the cell or in vesicles. Based on their structural and functional characteristics, neurotransmitter receptors can be classified into two broad categories: metabotropic and ionotropic receptors. Ionotropic receptors form an ion channel pore. In contrast, metabotropic receptors are indirectly linked with ion channels on the plasma membrane of the cell through signal transduction mechanisms, often G proteins. Hence, G protein-coupled receptors are inherently metabotropic. Other examples of metabotropic receptors include tyrosine kinases or guanylyl cyclase receptors. Both receptor types are activated by specific neurotransmitters. When an ionotropic receptor is activated, it opens a channel that allows ions such as Na+, K+, or Cl- to flow. In contrast, when a metabotropic receptor is activated, a series of intracellular events are triggered that can also result in ion channels opening but must involve a range of second messenger chemicals.
The translations of metabotropic receptor from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «metabotropic receptor» in English.
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «metabotropic receptor».
FREQUENCY OF USE OF THE TERM «METABOTROPIC RECEPTOR» OVER TIME
The graph expresses the annual evolution of the frequency of use of the word «metabotropic receptor» during the past 500 years. Its implementation is based on analysing how often the term «metabotropic receptor» appears in digitalised printed sources in English between the year 1500 and the present day.
Examples of use in the English literature, quotes and news about metabotropic receptor
10 ENGLISH BOOKS RELATING TO «METABOTROPIC RECEPTOR»
Discover the use of metabotropic receptor in the following bibliographical selection. Books relating to metabotropic receptor and brief extracts from same to provide context of its use in English literature.
Nerve Cells and Nervous Systems: An Introduction to Neuroscience
Combination with an ionotropic receptor leads to ionic current passing through
the cell, since the ionotropic receptor forms the ion channel and transmitter-
receptor combination opens the channeL Combination with a metabotropicreceptor ...
A.G. Brown, 2001
Identification of a Novel Metabotropic Glycine Receptor and ...
In the metabotropic receptor project, I used pharmacological and
electrophysiological experiments to establish the presence and effect of mGlyRs
on calcium channel currents and bipolar cell synaptic signaling. I took advantage
of the fact that ...
Mingli Hou, 2007
Discovering Biological Psychology
(b) Metabotropic Receptor What is the advantage to an organism of evolving a
slower, more complicated system? The answer is that the metabotropic receptor
provides the possibility of a much greater variety of responses to the release of ...
Laura Freberg, 2009
Although the effects of metabotropic receptor across all metabotropic effects:
activation vary, the following fundamental properties are nearly universal • Slow
onset: Metabotropic receptor activation acts indirectly on ion channels. Thus, the
Peggy Mason, PhD, 2011
Neuroscience: From the Molecular to the Cognitive: From the ...
of metabotropic receptor activation seemed most likely. However, studies by Koh
et al. (1991) revealed that the broad spectrum selective metabotropic receptor
agonist, trans- 1-aminocyclopentane-1,3-dicarboxylic acid (tACPD), was not ...
Floyd E. Bloom, 1994
Textbook of Drug Design and Discovery, Third Edition
188.8.131.52 Metabotropic receptor ligands Characterization of metabotropic Glu
receptors did not really proceed until after the cloning of the different subtypes in
the early nineties. Thus, the research within this group of receptors has been
going on ...
Tommy Liljefors, Povl Krogsgaard-Larsen, Ulf Madsen, 2003
Design principles of sensory receptors
These qualitatively different signal transduction pathways are now usually called
ionotopic or metabotropic. Historically, the term metabotropic receptor has been
introduced to dis- tinguish a subtype of glutamate receptors that triggers chem- ...
Dieter Wicher, 2013
Pediatric Epilepsy: Diagnosis and Therapy :Third Edition
Modulating the activation or inhibition of metabotropic receptor activation by
excitatory transmission plays an important role in modifying neuronal function
over both short- and long-term periods relative to seizure activity. Metabotropic ...
John M. Pellock MD, Blaise F. Bourgeois MD, Edwin Dodson MD, 2007
Nonstimulated metabotropic receptor Copyright 2011 Cengage Learning. ... A
metabotropic receptor acts a little like that. When a neurotransmitter attaches to a
metabotropic receptor, it bends the receptor protein that goes through the ...
James Kalat, 2012
Exploring the Thalamus
t. G protein effector protein timel -^- time 2 -▻ time 3 Metabotropic Receptor other
second net effects messenger e Figure 1 Schematic depiction of an ionotropic
and a metabotropic receptor, each shown repeatedly at different times. For the ...
S. Murray Sherman, Ray W. Guillery, 2001
2 NEWS ITEMS WHICH INCLUDE THE TERM «METABOTROPIC RECEPTOR»
Find out what the national and international press are talking about and how the term metabotropic receptor is used in the context of the following news items.
Nanaimo teen heads to battle of the brains
She answered questions such as: What secondary messenger gets released at a metabotropic receptor? Answer: A G-protein. Or: What ... «Times Colonist, May 14»
Is There a Gene for Postpartum Depression?
A classic metabotropic receptor, GABAB is g protein-coupled and participates in a signal transduction process that eventually results in the ... «Psychiatric Times, Dec 08»
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