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nucleotidase

Meaning of "nucleotidase" in the English dictionary

DICTIONARY

PRONUNCIATION OF NUCLEOTIDASE

ˌnjuːklɪəˈtaɪdeɪs


GRAMMATICAL CATEGORY OF NUCLEOTIDASE

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Nucleotidase is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES NUCLEOTIDASE MEAN IN ENGLISH?

Nucleotidase

A nucleotidase is a hydrolytic enzyme that catalyzes the hydrolysis of a nucleotide into a nucleoside and a phosphate. For example, it converts adenosine monophosphate to adenosine, and guanosine monophosphate to guanosine. Nucleotidases have an important function in digestion in that they break down consumed nucleic acids. They can be divided into two categories, based upon the end that is hydrolyzed: ▪ EC 3.1.3.5: 5'-nucleotidase - NT5C, NT5C1A, NT5C1B, NT5C2, NT5C3 ▪ EC 3.1.3.6: 3'-nucleotidase - NT3 5'-Nucleotidases cleave off the phosphate from the 5' end of the sugar moiety. They can be classified into various kinds depending on their substrate preferences and subcellular localization. Membrane-bound 5'-nucleotidases display specificity toward adenosine monophosphates and are involved predominantly in the salvage of preformed nucleotides and in signal transduction cascades involving purinergic receptors. Soluble 5'-nucleotidases are all known to belong to the haloacid dehalogenase superfamily of enzymes, which are two domain proteins characterised by a modified Rossman fold as the core and variable cap or hood.

Definition of nucleotidase in the English dictionary

The definition of nucleotidase in the dictionary is a biochemical catalyst that facilitates the process of hydrolyzing or splitting a nucleotide and turning it into a phosphate and a nucleoside.

WORDS THAT RHYME WITH NUCLEOTIDASE

ace · base · bass · case · case-by-case · dace · database · dipeptidase · disaccharidase · face · galactosidase · grace · hyaluronidase · interface · lace · marketplace · oxidase · peptidase · peroxidase · vendace

WORDS THAT BEGIN LIKE NUCLEOTIDASE

nucleoli · nucleolus · nucleon · nucleon number · nucleonic · nucleonically · nucleonics · nucleophile · nucleophilic · nucleophilicity · nucleoplasm · nucleoplasmatic · nucleoplasmic · nucleoprotein · nucleoside · nucleosomal · nucleosome · nucleosynthesis · nucleosynthetic · nucleotide

WORDS THAT END LIKE NUCLEOTIDASE

amidase · aminopeptidase · diamine oxidase · endopeptidase · exopeptidase · glucosidase · glucuronidase · glycosidase · hexosaminidase · monoamine oxidase · neuraminidase

Synonyms and antonyms of nucleotidase in the English dictionary of synonyms

SYNONYMS

Translation of «nucleotidase» into 25 languages

TRANSLATOR

TRANSLATION OF NUCLEOTIDASE

Find out the translation of nucleotidase to 25 languages with our English multilingual translator.

The translations of nucleotidase from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «nucleotidase» in English.
zh

Translator English - Chinese

核苷酸
1,325 millions of speakers
es

Translator English - Spanish

nucleotidasa
570 millions of speakers
en

English

nucleotidase
510 millions of speakers
hi

Translator English - Hindi

nucleotidase
380 millions of speakers
ar

Translator English - Arabic

نوكليوتيداز
280 millions of speakers
ru

Translator English - Russian

нуклеотидаза
278 millions of speakers
pt

Translator English - Portuguese

nucleotidase
270 millions of speakers
bn

Translator English - Bengali

nucleosynthetic
260 millions of speakers
fr

Translator English - French

nucleotidase
220 millions of speakers
ms

Translator English - Malay

Nukleosynthetic
190 millions of speakers
de

Translator English - German

Nukleotidase
180 millions of speakers
ja

Translator English - Japanese

ヌクレオチダーゼ
130 millions of speakers
ko

Translator English - Korean

뉴 클레오
85 millions of speakers
jv

Translator English - Javanese

Nukleosintetik
85 millions of speakers
vi

Translator English - Vietnamese

nucleotidase
80 millions of speakers
ta

Translator English - Tamil

nucleosynthetic
75 millions of speakers
mr

Translator English - Marathi

न्यूक्लिओसिन्थेटिक
75 millions of speakers
tr

Translator English - Turkish

nükleosentetik
70 millions of speakers
it

Translator English - Italian

nucleotidase
65 millions of speakers
pl

Translator English - Polish

nukleotydazy
50 millions of speakers
uk

Translator English - Ukrainian

нуклеотидаза
40 millions of speakers
ro

Translator English - Romanian

nucleotidază
30 millions of speakers
el

Translator English - Greek

-νουκλεοτιδάση
15 millions of speakers
af

Translator English - Afrikaans

nucleotidase
14 millions of speakers
sv

Translator English - Swedish

nukleotidas
10 millions of speakers
no

Translator English - Norwegian

nukleotidase
5 millions of speakers

Trends of use of nucleotidase

TRENDS

TENDENCIES OF USE OF THE TERM «NUCLEOTIDASE»

Principal search tendencies and common uses of nucleotidase
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «nucleotidase».

Examples of use in the English literature, quotes and news about nucleotidase

EXAMPLES

10 ENGLISH BOOKS RELATING TO «NUCLEOTIDASE»

Discover the use of nucleotidase in the following bibliographical selection. Books relating to nucleotidase and brief extracts from same to provide context of its use in English literature.
1
Schiff's Diseases of the Liver
Sotil E, Jensen D. Serum enzymes associated with cholestasis. Clin Liver Dis 2004;8:41.This paper discusses the use of alkaline phosphatase, 5′- nucleotidase, and γ-glutamyltranspeptidase in the evaluation of cholestatic liver disorders.
Eugene R. Schiff, Willis C. Maddrey, Michael F. Sorrell, 2011
2
The Enzymes
I5 Nucleotide Ph0sj2/iomouoesterases GEORGE I. DRUMMOND . MASANOBU YAMAMOTO 1.5'-Nucleotidase . . . . Bacterial 5'-Nucleotidase . Yeast 5'- Nucleotidase . . . Snake Venom 5'-Nucleotidase . . . Bull Seminal Plasma 5'- Nucleotidase ...
Paul D. Boyer, 1971
3
Deoxynucleoside Analogs in Cancer Therapy
Nucleotide and nucleoside analogues as inhibitors of cytosolic 5′-nucleotidase I from heart. Biochemistry 37,9043–9051. 70. Skladanowski, A. C., Hoffmann, C. S., Krass, J. D., Makarewicz, W., and Jastorff, B. (1995). Different substrate ...
Godefridus J Peters, 2007
4
Purine and Pyrimidine Metabolism in Man X
2.4. Purification. of. ecto-5'-nucleotidase. Ecto-5' -nucleotidase was further purified by Concanavalin A-Sepharose affinity chromatography and elution with 6 % methyl-a-D-mannopiranoside in 50 mM Tris, 0.5 M NaCl, ImM MgCl2, 1 mM CaCl2, ...
Esther Zoref-Shani, Oded Sperling, 2000
5
Molecular Biology of Aging
Using a Sephadex G-100 gel filtration and sedimentation cen- trifugation in a sucrose gradient, the molecular weight of this inhibitor of S'-nucleotidase was found to be 35,000 as compared with other proteins of known molecular weight ( Fig 2).
Avril D. Woodhead, Anthony D. Blackett, Alexander Hollaender, 1985
6
Enzyme Technology : Pacemaker of Biotechnology
Based on the end the hydrolytic nucleotidase is categorized into 5'-nucleotidase ( 5 '-NT) and 3'-nucleotidase (3 '-NT). 5 '-Nucleotidase removes phosphate from the 5' end of the sugar moiety and 3'-nucleotidase removes phosphate from the ...
Prasad Nooralabettu Krishna, 2011
7
Adenosine and Adenine Nucleotides: From Molecular Biology to ...
First, we tested whether the ischemic preconditioning procedure increases ecto-5 '-nucleotidase activity and adenosine release during reperfusion [12]. In anesthetized open-chest dogs, after intravenous administration of heparin (500 U / kg), ...
Luiz Belardinelli, A. Pelleg, 1995
8
Springer Handbook of Enzymes:
[23 [24 [25 [26 [27 [28 [29 [30 [31 [32 [33 [34 [35 [36 [37 [38 [39 [40 Naito, Y.; Lowenstein, J.M.: 5'-Nucleotidase from rat heart. Biochemistry, 20,5188-5194( 1981) Broad, D.F.; Smith, J.T.: Escherichia coli 5'-nucleotidase: purification, properties ...
Dietmar Schomburg, Ida Schomburg, Antje Chang, 2002
9
Handbook of Venoms and Toxins of Reptiles
weak 5′ nucleotidase activity (Ouyang and Huang, 1986). Also, differentiation of these nucleotidases has become more complicated since T. gramineus 5′ nucleotidase is also known to exhibit ADPase activity (Ouyang and Huang, 1983) .
Stephen P. Mackessy, 2009
10
Wintrobe's Clinical Hematology
31P NMR study of erythrocytes from a patient with hereditary pyrimidine-5′- nucleotidase deficiency. Proc Natl Acad Sci U S A 1983;80(1):169–172. Valentine WN, et al. Studies on human erythrocyte nucleotide metabolism. II. Nonspherocytic ...
John P. Greer, Daniel A. Arber, Bertil Glader, 2013

2 NEWS ITEMS WHICH INCLUDE THE TERM «NUCLEOTIDASE»

Find out what the national and international press are talking about and how the term nucleotidase is used in the context of the following news items.
1
Calcification of joints and arteries: second report with novel NT5E …
CD73 is a membrane-bound ecto-5′-nucleotidase that catalyzes the conversion of AMP to adenosine. One of the many functions of adenosine ... «Nature.com, Jul 15»
2
Advertorial: Introduction of a Convenient, Non-Radioactive Universal …
The assay couples the kinase reaction with the nucleotidase CD39L2, releasing phosphate from the ADP that is produced. The free phosphate ... «Genetic Engineering News, Dec 12»
REFERENCE
« EDUCALINGO. Nucleotidase [online]. Available <https://educalingo.com/en/dic-en/nucleotidase>. May 2024 ».
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