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Meaning of "probenecid" in the English dictionary

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DICTIONARY
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PRONUNCIATION OF PROBENECID

probenecid  [prəʊˈbɛnɪsɪd] play
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GRAMMATICAL CATEGORY OF PROBENECID

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Probenecid is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES PROBENECID MEAN IN ENGLISH?

Probenecid

Probenecid is a uricosuric drug that increases uric acid excretion in the urine. It is primarily used in treating gout and hyperuricemia. Probenecid was developed as an alternative to caronamide to competitively inhibit renal excretion of some drugs, thereby increasing their plasma concentration and prolonging their effects.

Definition of probenecid in the English dictionary

The definition of probenecid in the dictionary is a drug used to increase the excretion of uric acid in urine as a treatment for gout.

WORDS THAT RHYME WITH PROBENECID


acid
ˈæsɪd
blessed
ˈblɛsɪd
bombycid
ˈbɒmbɪsɪd
Cid
sɪd
culicid
kjuːˈlɪsɪd
cursed
ˈkɜːsɪd
cussed
ˈkʌsɪd
dytiscid
dɪˈtɪsɪd
fancied
ˈfænsɪd
flaccid
ˈflæksɪd
inviscid
ɪnˈvɪsɪd
lucid
ˈluːsɪd
mysid
ˈmaɪsɪd
placid
ˈplæsɪd
rancid
ˈrænsɪd
Seleucid
sɪˈluːsɪd
tortricid
ˈtɔːtrɪsɪd
tubificid
tjuːˈbɪfɪsɪd
unpolicied
ʌnˈpɒlɪsɪd
viscid
ˈvɪsɪd

WORDS THAT BEGIN LIKE PROBENECID

probationally
probationary
probationary assistant
probationer
probationership
probative
probatively
probatory
probe
probeable
prober
probing
probingly
probiotic
probit
probity
problem
problem area
problem page
problem-free

WORDS THAT END LIKE PROBENECID

acetic acid
adipic acid
amino acid
ascorbic acid
carboxylic acid
cercopithecid
citric acid
fatty acid
folic acid
gamma-aminobutyric acid
hyaluronic acid
hydrochloric acid
hydroxy acid
lactic acid
lysergic acid
nonessential amino acid
nucleic acid
omega-3 fatty acid
scolecid
sulfuric acid

Synonyms and antonyms of probenecid in the English dictionary of synonyms

SYNONYMS

Translation of «probenecid» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF PROBENECID

Find out the translation of probenecid to 25 languages with our English multilingual translator.
The translations of probenecid from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «probenecid» in English.

Translator English - Chinese

丙磺舒
1,325 millions of speakers

Translator English - Spanish

probenecid
570 millions of speakers

English

probenecid
510 millions of speakers

Translator English - Hindi

प्रोबेनेसिड
380 millions of speakers
ar

Translator English - Arabic

البروبينسيد
280 millions of speakers

Translator English - Russian

пробенецид
278 millions of speakers

Translator English - Portuguese

probenecida
270 millions of speakers

Translator English - Bengali

probenecid
260 millions of speakers

Translator English - French

probénécide
220 millions of speakers

Translator English - Malay

Probenecid
190 millions of speakers

Translator English - German

Probenecid
180 millions of speakers

Translator English - Japanese

プロベネシド
130 millions of speakers

Translator English - Korean

프로 베네 시드
85 millions of speakers

Translator English - Javanese

Probenecid
85 millions of speakers
vi

Translator English - Vietnamese

probenecid
80 millions of speakers

Translator English - Tamil

ப்ரோபினெசிட்
75 millions of speakers

Translator English - Marathi

प्रोबेनेसिड
75 millions of speakers

Translator English - Turkish

probenesid
70 millions of speakers

Translator English - Italian

probenecid
65 millions of speakers

Translator English - Polish

probenecyd
50 millions of speakers

Translator English - Ukrainian

пробенецид
40 millions of speakers

Translator English - Romanian

probenecid
30 millions of speakers
el

Translator English - Greek

προβενεσίδη
15 millions of speakers
af

Translator English - Afrikaans

probenesied
14 millions of speakers
sv

Translator English - Swedish

probenecid
10 millions of speakers
no

Translator English - Norwegian

probenecid
5 millions of speakers

Trends of use of probenecid

TRENDS

TENDENCIES OF USE OF THE TERM «PROBENECID»

The term «probenecid» is regularly used and occupies the 105.785 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Regularly used
51
/100
The map shown above gives the frequency of use of the term «probenecid» in the different countries.
Principal search tendencies and common uses of probenecid
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «probenecid».

FREQUENCY OF USE OF THE TERM «PROBENECID» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «probenecid» during the past 500 years. Its implementation is based on analysing how often the term «probenecid» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about probenecid

EXAMPLES

10 ENGLISH BOOKS RELATING TO «PROBENECID»

Discover the use of probenecid in the following bibliographical selection. Books relating to probenecid and brief extracts from same to provide context of its use in English literature.
1
Calcium Signaling, Second Edition
One clue regarding the mechanism of this transport stems from reports that leakage is blocked by probenecid and sulfinpyrazone. These drugs block anion transport in a variety of cells [85-88]. However, probenecid blocks several different ...
James W. Putney, Jr., 2005
2
METHODS IN CELL BIOLOGY,VOLUME 31: VESICULAR TRANSPORT, PART ...
We confirmed this hypothesis by blocking clearance of the fluorescent dyes from mouse macrophages with probenecid or sulfinpyrazone, drugs that are known to inhibit organic-anion transport in epithelia (T. H. Steinberg et al., 1987).
Alan Michael Tartakoff, 1989
3
Drug Therapy in Nursing
Drugs Significantly Different From [P| Allopurinol Probenecid (Benemid, Probalan ) and sulfinpyrazone (Antu- rane) are also uricosuric drugs, which differ from allopurinol by their mechanism of action. Allopurinol works by inhibiting uric acid  ...
Diane S. Aschenbrenner, Samantha J. Venable, 2009
4
Drug-Drug Interactions, Second Edition
Interaction with Probenecid Probenecid has been reported to inhibit renal elimination of many drugs: acyclovir (325,326), allopurinol (327), bumetanide ( 328), cephalosporins (329–334), cidofovir (335), ciprofloxacin (336), famotidine ( 337), ...
A. David Rodrigues, 2008
5
Foye's Principles of Medicinal Chemistry
Because colchicine does not lower serum urate levels, it has been found to be beneficial to combine colchicine with a uricosuric agent, particularly probenecid. It is a potent drug, being effective at doses of approximately 1 mg, but doses as ...
Thomas L. Lemke, David A. Williams, 2012
6
Modern Pharmacology with Clinical Applications
Probenecid When probenecid (ColBENEMID) is given in sufficient amounts, it will block the active reabsorption of uric acid in the proximal tubules following its glomeritlar filtration, thereby increasing the amount of urate eliminated. In contras1.
Charles R. Craig, Robert E. Stitzel, 2004
7
Analytical Toxicology for Clinical, Forensic and ...
Probenecid not only inhibits the active tubular secretion of drugs but must also inhibit more active transport processes in the body, resulting in (extreme) tiredness (22, 23). Therefore it is difficult to understand why athletes should attempt to take ...
Hans Brandenberger, Robert A. A. Maes, 1997
8
Drug Transporters
probenecid inhibits several renal organic anion transporters, explaining its action on the excretion of various anionic drugs. Using different expression systems and test anions, human OAT1 was inhibited by probenecid with IC50 or Ki values ...
Martin F. Fromm, Richard B. Kim, 2010
9
Clinical Infectious Diseases: A Practical Approach
Probenecid blocks active renal tubular secretion of cidofovir. There are minimal data on cidofovir phar- macokinetics in patients with renal insufficiency or requiring dialysis. Limited evidence shows that CSF concentrations of cidofovir are low.
Richard K. Root, 1999
10
Doping in Sports
Probenecid (4-(dipropylsulfamoyl)benzoic acid) is widely used as a uricosuric agent in the treatment of chromic gout and as an adjunct to therapy with penicillins and other antibiotics to enhance plasma antibacterial concentrations ...
Detlef Thieme, Peter Hemmersbach, 2009

10 NEWS ITEMS WHICH INCLUDE THE TERM «PROBENECID»

Find out what the national and international press are talking about and how the term probenecid is used in the context of the following news items.
1
Disrupting Na + ,HCO 3 – -cotransporter NBCn1 (Slc4a7) delays …
... HCO3−-free solutions with nominally CO2-free air; pH was adjusted to 7.4 at 37 °C. Solutions contained 5 mM probenecid to inhibit BCECF ... «Nature.com, Jul 15»
2
United States: Two Recent Court Decisions Clarify "Reliance …
FDA first approved colchicine in combination with probenecid in 1961 for the treatment of gout, and subsequently approved a single ingredient ... «Mondaq News Alerts, Jul 15»
3
A Word from Dr. Pfenninger: Gout once seen as the 'rich man's …
This medication is ideal in overproducers. To increase elimination from the kidneys in under-excretors, another drug can be used (probenecid). «Midland Daily News, Jul 15»
4
Horizon Pharma plc Announces the US Patent and Trademark Office …
Monitor ammonia levels closely -- Probenecid: May affect renal excretion of metabolites of RAVICTI, including PAGN and PAA. About Urea ... «MarketWatch, Jun 15»
5
Here Is The Reason Cats Are Such Finicky Eaters
The team also found that probenecid, a chemical known to reduce bitter tastes in humans, also carries out the same function in cats. A study ... «Tech Times, Jun 15»
6
PBAC greenlights rheumatology drugs
The recommendation was made on the basis of a clinical need for an alternative to probenecid. But the committee also rejected applications for ... «6minutes, May 15»
7
Guidelines address 'suboptimal' gout management
Probenecid, benzbromarone or febuxostat can be used as a second line. In patients with renal impairment, allopurinol should begin at a low ... «6minutes, Apr 15»
8
Amoxicillin/probenecid effectively treats syphilis in HIV patients
A daily combination of high-dose amoxicillin and probenecid was an effective syphilis treatment in patients with HIV infection, according to ... «Healio, Apr 15»
9
UFC Hires Former IRS Shitbag, Presumably To Oppress Its Athletes
... pemoline, tetracosactide, ritalin, probenecid, celestone, amineptine, ... bronchodilators, clenbuterol, ephedrine, norbolethone, probenecid, ... «Deadspin, Apr 15»
10
FSC Laboratories, Inc. to Market Cefaclor for Oral Suspension in the …
As with other beta-lactam antibiotics, renal secretion of cefaclor is inhibited by probenecid. Exercise caution in patients with history of ... «Business Wire, Mar 15»

REFERENCE
« EDUCALINGO. Probenecid [online]. Available <https://educalingo.com/en/dic-en/probenecid>. May 2024 ».
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