Meaning of "spironolactone" in the English dictionary

ETYMOLOGY OF THE WORD SPIRONOLACTONE

From spiro-² + linking syllable -no- + lactone.

Etymology is the study of the origin of words and their changes in structure and significance.

PRONUNCIATION OF SPIRONOLACTONE

spironolactone  [ˌspaɪrənəʊˈlæktəʊn]

GRAMMATICAL CATEGORY OF SPIRONOLACTONE

Spironolactone is a noun.

A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES SPIRONOLACTONE MEAN IN ENGLISH?

Spironolactone

Spironolactone , commonly referred to simply as "spiro", and marketed primarily under the brand name Aldactone in most countries, is a synthetic, steroidal antimineralocorticoid agent with additional antiandrogen and weak progestogen properties, as well as some indirect estrogen and glucocorticoid effects. It is used primarily as a diuretic and antihypertensive, but may also be employed for the purpose of reducing elevated or unwanted androgen activity in the body. It acts predominantly as a competitive antagonist of the aldosterone receptor, and belongs to a class of pharmaceutical drugs known as potassium-sparing diuretics. Spironolactone is a relatively old drug, having been introduced clinically in 1959. Some have predicted that spironolactone will be less commonly used in cardiovascular conditions as the newer agents like the structurally-related compound eplerenone are more selective and lack many of the side effects and actions of spironolactone that are undesirable in that particular patient population. However, spironolactone remains more widely used as an antiandrogen than eplerenone for patients in whom this effect is a main goal.

Definition of spironolactone in the English dictionary

The definition of spironolactone in the dictionary is a diuretic that increases water loss from the kidneys and is much used to treat oedema in heart and kidney failure.

TRANSLATION OF SPIRONOLACTONE

Find out the translation of spironolactone to 25 languages with our English multilingual translator.

The translations of spironolactone from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «spironolactone» in English.

• Translator English - Chinese: 安体舒通
• Translator English - Spanish: espironolactona
• English: spironolactone
• Translator English - Hindi: स्पैरोनोलाक्टोंन
• Translator English - Arabic: سبيرونولاكتون
• Translator English - Russian: спиронолактон
• Translator English - Portuguese: espironolactona
• Translator English - Bengali: spironolactone
• Translator English - French: spironolactone
• Translator English - Malay: Spironolactone
• Translator English - German: Spironolacton
• Translator English - Japanese: スピロノラクトン
• Translator English - Korean: 스피로 노 락톤
• Translator English - Javanese: Spironolactone
• Translator English - Vietnamese: spironolactone
• Translator English - Tamil: ஸ்பைரோனோலாக்டோன்
• Translator English - Marathi: स्पिरोनॉलॅक्टोन
• Translator English - Turkish: spironolakton
• Translator English - Italian: spironolattone
• Translator English - Polish: spironolakton
• Translator English - Ukrainian: спиронолактон
• Translator English - Romanian: spironolactona
• Translator English - Greek: σπιρονολακτόνη
• Translator English - Afrikaans: spironolaktoon
• Translator English - Swedish: spironolakton
• Translator English - Norwegian: spironolakton

10 ENGLISH BOOKS RELATING TO «SPIRONOLACTONE»

Discover the use of spironolactone in the following bibliographical selection. Books relating to spironolactone and brief extracts from same to provide context of its use in English literature.

Interactions Between Aldosterone, Spironolactone and the ...

We have reported that rats subjected to partial nephrectomy (PNx) or administration of marinobufagenin (MBG) developed an increase in blood pressure, heart size, diastolic dysfunction, and cardiac fibrosis.

Amjad Shidyak, 2007

Spironolactone

Spironolactone (marketed under the trade names Aldactone, Novo-Spiroton, Aldactazide, Spiractin, Spirotone, Verospiron or Berlactone), commonly referred to as simply spiro, is a diuretic and is used as an antiandrogen.

Jesse Russell, Ronald Cohn, 2012

Articles on Furones, Including: Ascorbic Acid, Vitamin C, ...

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online.

Hephaestus Books, 2011

Articles on Spiro Compounds, Including: Spironolactone, ...

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online.

Hephaestus Books, 2011

Effect of Spironolactone on Acute Mountain Sickness

This study examined the effectiveness of Spironolactone as a prophylactic agent for the prevention of Acute Mountain Sickness (AMS).

Richard F. Larsen, P. B. Rock, U.S. Army Research Institute of Environmental Medicine, 1985

Pharmaceutical Chemistry of Antihypertensive Agents

Data is supported by more than 1400 references and 300 chemical structures. This book is essential reading for physicians and pharmaceutical researchers, as well as pharmaceutical chemistry students.

Gyorgy Szasz, Zsuzsanna Budvari-Barany, 1990

Spiro Compounds: Anemonin, Arterolane, Atiprimod, Atrane, ...

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online.

Source Wikipedia, 2013

Hypertension and You: Old Drugs, New Drugs, and the Right ...

This book shows how medications can be prescribed more wisely to achieve better results and gives patients the knowledge they need to capably discuss their medications with their health care providers.

Samuel J. Mann, 2012

Role of Aldosterone in Cardiac Remodeling Post-myocardial ...

High salt diet cardiac fibrosis by activating cardiac aldosterone .

Avtar Lal, 2008

Clinical Pharmacology and Therapeutics of Hypertension

This volume reviews comprehensively the present understanding of the clinical pharmacology and therapeutics of currently available antihypertensive agents.

Gordan McInnes, 2008

10 NEWS ITEMS WHICH INCLUDE THE TERM «SPIRONOLACTONE»

Find out what the national and international press are talking about and how the term spironolactone is used in the context of the following news items.

The Frustrating Complexity of Adult Acne

Spironolactone was first developed in 1957 and used to treat hypertension and patients with heart failure. It's a diuretic that causes people to urinate more and ... «Racked, Apr 15»

How to treat menopausal symptoms for a few cents a day

One of the unusual consequences of using spironolactone is that it has a feminizing ... For me, spironolactone has been a wonderful drug for the treatment of ... «The Ridgefield Press, Apr 15»

Study: Routine potassium monitoring unnecessary for young women …

A low rate of hyperkalemia was identified in young women taking spironolactone to treat acne, which was comparable to a baseline rate of hyperkalemia in the ... «Healio, Apr 15»

This Old Medicine May Be the Best 'New' Acne Treatment

No, it wasn't some hot new party drug, but rather, spironolactone, a prescription diuretic commonly used for people with high blood pressure—and sometimes ... «Elle.com, Apr 15»

Diuretic reduces skin atrophy associated with corticosteroid creams

Spironolactone, used to treat fluid retention in patients with oedema, heart ... the MR antagonist spironolactone, both compounds together or a placebo to the ... «The Pharmaceutical Journal, Mar 15»

Spironolactone for Hormonal Acne: Is Routine Potassium Monitoring …

(HealthDay News) — Healthy young women taking spironolactone for acne have no increased rate of hyperkalemia, according to a study published online ... «Monthly Prescribing Reference, Mar 15»

Topical Spironolactone May Limit Skin Thinning From Steroids

by a pharmacological agent (a blocker of the receptor of the hormone): spironolactone. This drug has been used for decades as an anti-hypertensive drug. «Medical Research News and Interviews on MedicalResearch.com, Mar 15»

Spironolactone drug reduces side effects of corticosteroid-based …

Basic research on blood pressure has led researchers from Inserm (Inserm Unit 1138, "Cordeliers Research Centre") to obtain unexpected results: drugs used to ... «News-Medical.net, Mar 15»

Common antibiotic taken with a diuretic linked to sudden death

Spironolactone, a diuretic used to treat heart failure with side effects including hyperkalaemia (raised blood potassium levels), is associated with an increased ... «The Pharmaceutical Journal, Feb 15»

Antibiotic, Spironolactone Combo Ups Sudden Death in Elderly

Prescribing the widely used antibiotic trimethoprim-sulfamethoxazole in tandem with spironolactone, a diuretic used to treat patients with heart failure, can ... «Medscape, Feb 15»