PAROLE IN INGLESE ASSOCIATE CON «GYRASE»
gyrase
reverse
wiki
function
called
animation
helicase
topoisomerase
often
referred
simply
enzyme
that
relieves
strain
while
double
strand
being
unwound
this
causes
negative
supercoiling
bacterial
structure
essential
catalyzes
dependent
super
coiling
stranded
closed
gyrase
belongs
merriam
webster
breaking
rejoining
bonds
adjacent
nucleotides
generate
supercoiled
informa
healthcare
abstract
class
enzymes
known
topoisomerases
subunit
terminal
beta
pinwheel
entry
represents
repeat
parc
gyra
define
more
gyrases
composed
heterotypic
tetramers
subunits
encoded
gyrb
genes
aureus
topogen
product
background
highly
purified
type
from
escherichia
coli
uniprot
10 LIBRI IN INGLESE ASSOCIATI CON «GYRASE»
Scopri l'uso di
gyrase nella seguente selezione bibliografica. Libri associati con
gyrase e piccoli estratti per contestualizzare il loro uso nella letteratura.
1
Molecular Biology: Academic Cell Update Edition
Ciprofloxacin kills bacteria by inhibiting DNA gyrase. It is harmless to animals as
they do not use DNA gyrase for compacting their DNA. Supercoiled DNA One
strand passed through nick and resealed Strand nick Type I topoisomerases one
...
2
Cancer Research Supported Under Biomed1
Comparison of drug-promoted DNA cleavage mediated by topoisomerase II and
hy DNA gyrase (Milan, Newcastle and London) Mammalian topoisomerase II
shares structural, functional and mechanistic features with DNA gyrase, the ...
392 Other Functions of DNA Gyrase chapter 12: Cells maintain the superhelicity
of the chromosome within rather narrow Topoisomerases limits. This homeostatic
control is achieved by the antagonistic actions of gyrase and topo I.76 Some of ...
Arthur Kornberg, Tania A. Baker, 2005
4
Infectious Diseases in Immunocompromised Hosts
Currently, two major mechanisms have been defined: (1) alterations in the
bacterial DNA gyrase, the molecular target of the quinolone action; and (2)
reduction of drug accumulation in the cells.9" 10.2.3.1 Alterations in Bacterial
DNA Gyrase ...
Vassil St. Georgiev, 1997
5
Cell and Molecular Biology of Plastids
1989); E. coli gyrase is comprised of 95 kDa gyrase B and 105 kDa gyrase A
subunits (Reece and Maxwell 1991). A more recent proteomic study identified
gyrase A- and B-like subunits in proteinnucleic acid particles from purified P.
sativum ...
6
Bacterial Genomes: Physical Structure and Analysis
mutant but not in a gyrase mutant (Adams et al, 1992). However, gyrase does
seem to be capable of replacing topoisomerase IV if overexpressed. Gyrase may
supplement topoisomerase IV, since shifting a temperature-sensitive gyrase ...
F.J. de Bruijn, James R. Lupski, George M. Weinstock, 1998
7
Molecular Biology of DNA Topoisomerases and Its Application ...
DNA gyrase: structure and function. CRC Crii. Rev. Biochem MolBioL.2b. 335.
199L 4. Gellert. M.. Mizuuchi. K.. O'Dea. M. H.. and Nash. H. A.. DNA gyrase: an
enzyme that introduces superhelical turus into DNA. Proc. Natl Acad. Sci. USA..
73.
Toshiwo Andoh, Masao Oguro, Hideo Ikeda, 1992
8
Hyperthermophilic Enzymes
and ParE, which are homologous to GyrA and GyrB, respectively.9 However,
Topo IV has no DNA gyrase activity but, as is the case with the eukaryotic
enzyme, can relax both positively and negatively supercoiled DNA.10 In the
absence of ...
9
Links Between Recombination and Replication: Vital Roles of ...
and not (+), the true substrates for unlinking during replication. This is because
the systems used to produce the stalled replication intermediates contained
sufficient DNA gyrase to (?) supercoil the intermediates before or after stalling.
Proceedings of the National Academy of Sciences, 2002
10
Technological and Medical Implications of Metabolic Control ...
will lead to a change in DNA supercoiling, which in turn leads to a change in
transcription rates of topoisomerase I and DNA gyrase genes. Thus a change in
the level of DNA supercoiling in the global steady state is not only the result of the
...
Athel Cornish-Bowden, Maria Luz Cárdenas, 2000
10 NOTIZIE DOVE SI INCLUDE IL TERMINE «GYRASE»
Vedi di che si parla nei media nazionali e internazionali e come viene utilizzato il termine ino
gyrase nel contesto delle seguenti notizie.
So You Actually Drank the Water During Your Vacation?
Like other fluoroquinolones, ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV. It is bactericidal, and active against Gram ... «MedPage Today, giu 15»
Choppy waters
The standalone company will deal with early stage antibiotics R&D including the novel gyrase inhibitor AZD0914, currently in phase II for the ... «Financial Express, giu 15»
Say it with proteins: an alphabet of crystal structures
... recognition; and for proteins with holes that enclose DNA (A, from DNA gyrase) or puncture the membrane (O, from the toxin cytolysin A). «Nature.com, mag 15»
AstraZeneca spins out early-stage R&D for antibiotic compounds
The new unnamed company will take over development of AstraZeneca's novel gyrase inhibitor AZD0914 for gonorrhoea, currently in phase ll ... «The Pharmaceutical Journal, mar 15»
Antibiotic linked to nerve damage
All Fluoroquinolone Antibiotics are Topoisomerase Inhibitors, which means they work by attacking DNA gyrase and topoisomerase IV on ... «KING5.com, mar 15»
AZ spins out antibiotics R&D biz to focus on key pipelines
The stand-alone company will exclusively deal with early-stage antibiotics R&D, including the novel gyrase inhibitor AZD0914, currently in ... «In-PharmaTechnologist.com, mar 15»
AstraZeneca to spin off anti-infectives research
The new company's principal asset will be the novel gyrase inhibitor AZD0914, which is currently in Phase II clinical trials for treating ... «Royal Society of Chemistry, mar 15»
AstraZeneca Launches $40M Early-Stage Anti-Infectives R&D Unit
The new subsidiary will focus exclusively on R&D for AstraZeneca's early-stage antibiotic pipeline, including the gyrase inhibitor AZD0914, now ... «Genetic Engineering & Biotechnology News, feb 15»
Cystic Fibrosis Drug Quinsair For Pseudomonas Aeruginosa …
Specifically, the drug acts by inhibiting important bacteria enzymes for DNA replication, the bacterial DNA gyrase and topoisomerase IV ... «Cystic Fibrosis News Today, dic 14»
Researchers discover bacteria-killer from natural source
"We were able to show that cystobactamides act as gyrase inhibitors. They prevent the DNA of the bacteria from being compacted in a ... «HealthCanal.com, dic 14»
