«ACETYLATION»に関連する英語の本
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1
Reversible Protein
Acetylation
A comprehensive review of recent work on chromatin and non-histone proteins, this book arises from the interactions of a multidisciplinary group of scientists involved in the study of acetylation.
Novartis Foundation,
2004
2
Genetically Altered Expression of Polyamine
Acetylation ...
Overall, the data obtained with these novel murine models reveal a previously unrecognized regulatory linkage between polyamine and fat metabolism with mechanistic implications for understanding and addressing obesity.
3
Regulation of the
Acetylation of C/EBPbeta and Its ...
This work demonstrates that C/EBPbeta is acetylated by p300 and P/CAF, and may be deacetylated by HDAC1, consistent with acetylation of C/EBPbeta being a dynamic regulatory event.
4
Introduction to Drug Metabolism
G. Gordon Gibson, Paul Skett. o H Figure 1.40 The S-methylation of thiouracil. ln
general, unlike other conjugation reactions, methylation leads to a less polar
product and thus hinders excretion of the drug. 1.3.4 Acetylation Acetylation ...
G. Gordon Gibson, Paul Skett,
2001
5
Prostate Cancer: Signaling Networks, Genetics, and New ...
Through point mutational analyses and in vitro acetylation studies, a minimal
region of the AR was identified to function as a substrate of SirT1 deacetylation (1
). The AR acetylation motif is well conserved in different species, and mutations of
...
Richard G. Pestell, M. Milken, Marja T. Nevalainen,
2008
6
Regulation of the TGFbeta Signaling Pathway Through the ...
These studies detailed in this thesis reveal a novel post-translational modification of Smad2 that contributes to its transcriptional activity by altering the protein's subcellular localization, retaining the protein in the nucleus upon ...
Key concept • Histone acetylation occurs transiently at replication. • Histone
acetylation is associated with activation of gene expression. • Deacetylated
chromatin may have a more condensed structure. • Transcription activators are
associated ...
8
In Vivo Epigenetic Study of Histone
Acetylation Associated ...
This is the first study which shows that hyperacetylation of histones in liver nuclei can be correlated with amelioration of hepatic steatotis.
9
Histone
Acetylation by Ethanol as a Mechanism for Alcohol ...
Ethanol treatment increases gene expression covering a wide spectrum of cellular functions in the liver through mechanisms that are not clearly defined.
10
Trichostatin A Improves Histone
Acetylation in Bovine ...
With respect to AcH4K5 in bovine SCNT 8-cell embryos, our results confirmed a
previous study's finding that SCNT embryos are deficient in histone acetylation (
associated with gene activation) compared to IVF counterparts (Wee et al., 2006).
Amy Elizabeth Iager,
2008
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Fluoride may damage female reproductive system
Additionally, fluoride exposure reduced DNA methylation and histone acetylation, which are important for germline development and genomic ... «Food Consumer, 7月 15»
Panobinostat set for approval in Europe as multiple myeloma …
Panobinostat inhibits histone deacetylase, resulting in increased acetylation of histone proteins. If approved in the EU, the drug, which is ... «The Pharmaceutical Journal, 7月 15»
Epigenetic Therapy in Oncology Drug Pipeline Update 2015
Today a majority of drugs targets histone methylation and acetylation, also frequently dysregulated in cancer cells, in the form of inhibitors of ... «SYS-CON Media, 7月 15»
An overproduction of astellolides induced by genetic disruption of …
Overexpression of esaA, an ortholog of S. cerevisiae ESA1, led to acetylation of histone 4 lysine 12 and overproduction of four known SMs ... «Nature.com, 6月 15»
Novel pectin present in new olive mill wastewater
The pectic material presented a high molecular size and a low percentage of methyl esterification and acetylation. In comparison with ... «Teatro Naturale, 6月 15»
MYC in pancreatic cancer: novel mechanistic insights and their …
The impact of MYC on local chromatin acetylation has been addressed in several studies. The MYC co-factor transformation-transactivation ... «Nature.com, 6月 15»
Immunomodulatory drugs target IKZF1-IRF4-MYC axis in primary …
Bromodomain (BRD)-containing proteins regulate lysine acetylation, an important mechanism to regulate chromatin structure. BRD and ... «Nature.com, 6月 15»
James Latham capitalises on housing boom
Appetite was particularly strong for the timber merchant's modified wood product, which uses the acetylation process to ensure durability and ... «Investors Chronicle, 6月 15»
KLF4 regulates adult lung tumor-initiating cells and represses K-Ras …
We have reported that KLF4 interacts with histone acetyltransferase and regulates histone acetylation. KLF4 also interacts with histone ... «Nature.com, 6月 15»
Post Translational Modification: Antibody Enrichment for Mass …
Products and services are available for analysis of protein phosphorylation, acetylation, ubiquitination, methylation, succinylation, and caspase ... «Digital Journal, 6月 15»