«NONHISTONE»に関連する英語の本
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1
METHODS IN CELL BIOLOGY,VOLUME 18: CHROMATIN AND CHROMOSOMAL ...
are more immunoreactive than better differentiated and slow-growing hepatomas
7800 and 7787 when anti-Novikoff-nonhistone protein-DNA antibody was
employed. Normal liver chromatin differs antigenically from tumor chromatins; ...
Gary Stein, Janet Stein, Lewis J. Kleinsmith, 1978
2
Nuclear Cytology in Relation to Development
properties closely resembling those of some nonhistone proteins of eukaryotes (
Beyreuther, Adler, Geisler & Klemm, 1973). Like histones, nonhistone proteins
are synthesized outside the nucleus in the cytoplasm and are transported into the
...
3
PROG NUCLEIC ACID RES&MOLECULAR BIO
Mainly quantitative variations in nonhistone proteins with hepatocarcinogenesis
have also been reported by others (2-4). However, the use of antibodies and the
immunotransfer indicate that neoplasia may induce more extensive changes, ...
4
Systemic Lupus Erythematosus
NOMENCLATURE AND MOLECULAR BIOLOGY OF NONHISTONE
AUTOANTIGENS The significance of antibodies directed against nonhistone
protein antigens has increased with the ability to characterize their respective
antigens at the ...
Contrary to the histones which represent a narrow, well-defined group of basic
proteins, the nonhistone chromatin proteins represent a highly variable group of
acidic proteins of various functions. The molecular weight of these proteins is
very ...
344 Nonhistone DNA-Binding Proteins" chapter 10: Nonhistone chromosomal
proteins must also participate as enzymes and regula- DNA-Binding Proteins tors
in replication and transcription in chromatin. This complex group contains, in the
...
Arthur Kornberg, Tania A. Baker, 2005
7
Cell and Developmental Biology
Unlike histones, most of the nonhistone proteins are acidic, and they vary
qualitatively in different cell types of the same organism. Non-histone proteins are
complexed to areas of DNA whose information is being expressed. Hence it has
been ...
Dr. Sastry, Dr. Singh & Dr. Tomar, 2010
8
Biochemical Actions of Hormones
Nonhistone Proteins, Transcription, and Gene Expression The functional
importance of nonhistone (acidic) proteins has been emphasized by recent
experiments. Using reconstituted homologous and heterologous chromatins from
...
9
METHODS IN CELL BIOLOGY
DNA-BINDING PROTEINS Gretchen H. Stein 20. FRACTIONATION OF
NONHISTONE PROTEINS BY HISTONE-AFFINITY CHROMATOGRAPHY Alan
McClearly, Larry Nooden, and Lewis J. Kleinsmith 21. FRACTIONATION OF
NONHISTONE ...
10
ADVANCES IN CANCER RESEARCH
When chromatin was further fractionated, TAF activity was found in the pool of
nonhistone proteins (Tuan et al., 1973) (Fig. 10). The nonhistone protein pool
which contained angiogenesis activity was resolved into 20 protein moieties by ...
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Briggs Morrison trades lead role in AstraZeneca R&D for the helm of …
The epigenetics program is aimed at HDAC, an enzyme that modifies histone in DNA as well as nonhistone proteins involved in cell survival, ... «FierceBiotech, 6月 15»
The Aurora A-HP1γ pathway regulates gene expression and mitosis …
James T, Elgin S. Identification of a nonhistone chromosomal protein associated with heterochromatin in Drosophila melanogaster and its gene ... «BMC Blogs Network, 5月 15»
FDA Panel Falls Short of Recommending Panobinostat
It is an inhibitor of histone and nonhistone deacetylases. Novartis submitted evidence from two phase 3 studies and one phase 2 study in its ... «Medscape, 11月 14»
Epigenetics Targets May Enable Discovery of Novel Drugs
HDACs normally catalyze removal of acetyl groups from acetylated lysine residues in histones and nonhistone proteins, which helps to regulate ... «Genetic Engineering News, 10月 13»
4 Steps to Get Your ChIP Experiment Working
ChIP for histone modifications is unlikely to require cross-linking whereas nonhistone proteins such as transcription factors and proteins contained within DNA ... «Genetic Engineering News, 7月 13»
Editorial: HDAC inhibition begets more MDSCs
Emerging data also show that in addition to regulating acetylation of lysines within histones, HDAC enzymes regulate the acetylation of several nonhistone ... «Journal of Leukocyte Biology, 4月 12»
HDAC inhibitors overcome first hurdle
... but that's a very crude measure of drug activity, given the wide range of nonhistone target proteins. Acetylated histones “really haven't been ... «Nature.com, 1月 07»
