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1
Current Cardiovascular Drugs - 142페이지
Major trials have demonstrated the efficacy of streptokinase in the treatment of acute MI. Streptokinase reduced in-hospital mortality by 18% compared with standard therapy in the GISSI-1 trial, with this benefit being maintained for over 1 year.
William H. Frishman, Angela Cheng-Lai, James Nawarskas, 2005
2
Textbook of Coronary Thrombosis and Thrombolysis
Streptokinase, one of the first thrombolytic agents to be discovered, has now been used in many hundreds of thousands of patients with acute myocardial infarction. The drug was first discovered in 1933 by William Tillet, who called it fibrolysin ...
3
Meyler's Side Effects of Cardiovascular Drugs - 513페이지
The incidence of hemorrhagic complications is particularly high when high doses of streptokinase are used in the treatment of deep venous thrombosis (34). High-dose streptokinase thrombolysis for 2–3 days with an initial dose of 500 000 ...
4
Stroke: Investigation and management - 1158페이지
(1995) evaluated 20 patients (10 streptokinase, 10 placebo) within 5.2 hours (placebo) and 5.8 hours (streptokinase). There were three deaths in each treatment group, with a higher incidence of hemorrhage in the streptokinase group (n 1⁄4 3 ...
5
Drug Therapy in Nursing - 619페이지
Streptokinase (Streptase) is used in treating acute evolving MI, pulmonary embolism DVT, arterial thrombosis, or embolism, and to open occluded arteriovenous cannulas. Unlike alteplase, which works by attaching to the fibrin in a thrombus ...
Diane S. Aschenbrenner, Samantha J. Venable, 2009
6
Principles of Pharmacology: The Pathophysiologic Basis of ...
Streptokinase is a protein produced by 3-hemolytic streptococci as a component of that organism's tissue-destroying machinery. The pharmacologic action of streptokinase involves two steps—complexation and cleavage. In the complexation ...
Streptokinase Streptokinase [Strep-toe-KYE-nase] is an extracellular protein purified from culture broths of Group C 3-hemolytic streptococci." 1. Mechanism of action: Streptokinase has no enzymic activity. Instead, it forms an active one-to-one ...
Richard Finkel (PharmD.), Michelle Alexia Clark, Luigi X. Cubeddu, 2009
8
Heptinstall's Pathology of the Kidney - 1권 - 352페이지
This protein is not related to group A streptokinase (358) or to a recently described streptococcal dehydrogenase protein according to these authors (358,359). Amino acid sequence analysis and immunologic reactivity studies suggest that this ...
J. Charles Jennette, 2007
9
Proteolytic Enzymes - 파트 2 - 245페이지
streptokinase arc purified plasminogens and plasmins from human,2 monkey,3'4 baboon,3 chimpanzee,3 cat,4 dog,4 and rabbit5'6 plasmas. Several studies3-4'7 have been performed in an attempt to evaluate the comparative potency of ...
10
Drug Discovery: A History - 346페이지
DRUGS FROM BACTERIA Streptokinase was the first fibrinolytic agent to be employed in the clinic. It was isolated from cultures of P-haemolytic streptococci in 1945 by researchers working under the guidance of William Tillett at New York ...
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이연제약 유성락 회장, 향년 70세로 타계
국내 기업으로는 처음으로 소염효소제 원료인 스트렙토키나제의 발효합성 정제기술 개발에 성공했으며, 세계에서 두 번째로 Aminoglycoside계 항생제인 황산 아르 ... «의약뉴스, 8月 14»
2016년 생동재평가 대상 271품목 공개
가장 많은 성분으로는 스트렙토키나제ㆍ스트렙토도르나제로 25개가 포함됐다. 한올바이오파마의 뮤코스탑정, 한미약품의 뮤코라제정 등이 해당한다. 다음으로는 ... «디지틀보사, 2月 14»
아세틸카르니틴·콜린알포세레이트 생동면제 검토
... 방침"이라고 말했다. 한편, 이들 성분과 같은 내인성물질인 스트렙토도르나제-스트렙토키나제는 생동시험이 불가능하다는 이유로 생동 대상품목에서 빠진 바 있다. «데일리팜, 12月 13»
한미약품 뮤코라제정 등 1개월 판매정지
해당제품은 한미아스피린장용정100밀리그램, 뮤코라제정(스트렙토키나제,스트렙토도르나제분말), 써스펜이알서방정, 이트라정(이트라코나졸), 토바스트정20 ... «디지틀보사, 12月 12»
2012 생동재평가 대형품목 대거포함
8, 스트렙토키나제-스트렙토도르나제, 20. 9, 실로스타졸, 3. 10, 아목시실린·클라불란산칼륨, 149. 11, 아세트아미노펜·트라마돌염산염, 170. 12, 아세틸엘카르니틴 ... «디지틀보사, 1月 10»
