KSIĄŻKI POWIĄZANE ZE SŁOWEM «GLUCOKINASE»
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1
Glucokinase and Glycemic Diseases: From Basics to Novel ...
This volume is of great interest to basic and clinical diabetes researchers, geneticists, biochemists, physiologists and pharmacologists.
Franz M. Matschinsky, Mark A. Magnuson, 2004
2
Glucokinase: its regulation and role in liver metabolism
This book is about the hexokinase isoenzyme responsible for glucose phosphorylation in hepatocytes, commonly known as glucokinase.
ATP ADP H C H O C H OH C H OH C HO H C H OH C H O P Hexokinase
Glucokinase Glucose 6-phosphate D -Glucose ... Glucokinase Vmax Glucokinase
K m Hexokinase K m Glucokinase Glucose concentration, mmol/L V max
hexokinase ...
Richard A. Harvey (Ph. D.), Richard A. Harvey, Denise R. Ferrier, 2011
4
Marks' Basic Medical Biochemistry
One class of MODY is caused by mutations in the gene for pancreatic
glucokinase (a closely related isozyme of liver glucokinase) that affect its kinetic
properties (Km orVmax). Glucokinase is part of the mechanism that controls
release of ...
Michael A. Lieberman, Allan Marks, Alisa Peet, 2012
5
Joslin's Diabetes Mellitus: Edited by C. Ronald Kahn ... [et ...
TREATMENT Patients with glucokinase mutations rarely need any pharma-
cologic treatment (51,52). The majority of patients with glucokinase mutations (>
85%) are treated with diet alone. Avoiding unrefined carbohydrate may not be as
...
Elliott Proctor Joslin, C. Ronald Kahn, 2005
6
Metabolic Regulation in Mammals
sets the total amount of glucokinase present in liver cells. The high insulin to
glucagon ratio of the well-fed state induces whereas the low insulin to glucagon
ratio caused by fasting represses the synthesis of hepatic glucokinase. The
resulting ...
David Gibson, Robert A. Harris, 2003
7
Diabetes Mellitus: A Fundamental and Clinical Text
A Fundamental and Clinical Text Derek LeRoith, Simeon I. Taylor, Jerrold M.
Olefsky. gene, the genes encoding glucokinase, islet amyloid polypeptide and
glucose transporter 2 (40). IPF-1 also appears to mediate glucose-induced
stimulation ...
Derek LeRoith, Simeon I. Taylor, Jerrold M. Olefsky, 2004
8
Pancreatic Beta Cell in Health and Disease
Grimsby J, Taub R, Ellard S, Hattersley AT, Matschinsky FM (2005) Insights into
the structure and regulation of glucokinase from a novel mutation (V62M) which
causes maturity-onset diabetes of the young. J Biol Chem 280:14105–14113 27.
Susumu Seino, Graeme I. Bell, 2008
9
Molecular Pathogenesis of MODYs
1 Randle PJ: Glucokinase and candidate genes for type 2 (non-insulin-
dependent) diabetes mellitus. Diabetologia 1993;36:269–275. 2 Iynedjian PB:
Mammalian glucokinase and its gene. Biochem J 1993;293:1–13. 3 Van
Schaftingen E, ...
Franz M. Matschinsky, Mark A. Magnuson, 2000
10
Handbook of Endocrinology, Second Edition
GLUCOKINASE GENE Glucokinase (type IV hexokinase) catalyzes the first step
of glucose metabolism, phos- phorylation to glucose-6-phosphate, in the P cell
and the liver. The enzyme belongs to a family of hexokinases (type I-IV) but has a
...
George H. Gass, Harold M. Kaplan, 1996
WIADOMOŚCI, KTÓRE ZAWIERAJĄ SŁOWO «GLUCOKINASE»
Sprawdź, o czym dyskutuje się w prasie krajowej i zagranicznej oraz jak jest stosowane słowo
glucokinase w wiadomościach.
Diet-induced obesity impairs hypothalamic glucose sensing but not …
Glucokinase is the likely mediator of glucosensing in both glucose-excited and glucose-inhibited central neurons. Diabetes 2002; 51: ... «Nature.com, Cze 15»
Overeating may damage hepatic glucose uptake and disposition: A …
Control groups, although glucokinase protein did not differ between groups. In High.kcal vs. Control group, liver glycogen was reduced 27%, ... «Biotechin.Asia, Cze 15»
vTv Therapeutics Initiates Patient Dosing in the AGATA Study, a six …
The AGATA (Add Glucokinase Activator to Target A1c) study is a multi-center, double-blind, placebo- and active-controlled (sitagliptin), study to ... «Military Technologies, Cze 15»
Hua Medicine Files IND in US for Its Novel GKA-Based Diabetes Drug
... Drug (IND) application with the US Food and Drug Administration (FDA) for its novel 4th-Generation glucokinase activator (GKA) to treat Type ... «Marketwired, Mar 15»
Genetic testing identifies patients with monogenic diabetes
... a form of maturity-onset diabetes of the young, linked to mutations in the glucokinase gene. The condition causes lifelong mild hyperglycemia ... «Healio, Mar 15»
Mushroom extracts show blood sugar management potential: Study
Both mushrooms were associated with increases in glucokinase (GK) secretion, they added, and decreases in glycogen synthase kinase (GSK) ... «NutraIngredients-usa.com, Lut 15»
Prepare for the Pill to Make You Thin
At the same time, another player – a team of researchers from Imperial College, London – identified an enzyme called glucokinase which could ... «Newsweek, Sty 15»
Hua Medicine Raises $25 Million in Series B Financing to Start …
... Phase 2 clinical development of its most advanced asset HMS5552 (Sinogliatin), a novel 4th-generation glucokinase activator (GKA) for Type ... «Marketwired, Sty 15»
CREB3L3 May Be Target for Obesity, Diabetes Treatments
Genes for the glycolytic enzymes glucokinase and pyruvate kinase, in contrast, were found to be downregulated. These and other animal ... «MedPage Today, Gru 14»
Stay slim by eating desserts first before your main meal
Glucokinase, a brain protein, keeps track of how much glucose is eaten. If one's intake is too low, the brain will tell the body to find more starchy ... «Capital FM Kenya, Gru 14»
