KSIĄŻKI POWIĄZANE ZE SŁOWEM «MONOSPECIFICITY»
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Vaccine Research and Development: |:
A special point that needs to be stressed is the high monospecificity produced by
the polyclonal and monoclonal antibodies elicited by peptide immunogens with
the MAP approach. The monospecificity may be due to the homogeneity of the ...
2
Regulated Bioanalytical Laboratories: Technical and ...
Monospecificity: Monospecificity is functionally defined as the immunoreactivity of
an antiserum with its designated antigen (e.g., antihuman IgG, antihuman IgG Fc
piece, human IgG3 Fc piece, etc.). In practice, true monospecificity to naturally ...
A. CONTROL OF THE MONOSPECIFICITY OF AN IMMUNE SERUM Usually the
monospecificity of an immune serum is tested by using double diffusion,
immunoelectrophoretic analysis or crossed Immunoelectrophoresis which have a
certain ...
Jean Daussant, J. Mossé, John Griffith Vaughan, 1983
4
Monoclonal Antibodies: Principles and Practice
Monospecificity,. Commitment. to. One. Light. Chain Type, and Allelic Exclusion
The fact that the antibody gene rearrangements are orderly and monitored by the
cell for productive expression ensures that the great majority of cells express a ...
5
Immunology and the Quest for an Hiv Vaccine: A New Perspective
Between the numerous lymphocytes, there is variation in structural formation.
However, a particular individual lymphocyte only has receptors that are identical
one to another. This is called monospecificity because these identical lymphocyte
...
Dr Phd Bagasra, Donald Gene Phd Pace, 2012
6
METHODS IN CELL BIOLOGY,VOLUME 21A: NORMAL HUMAN TISSUE AND ...
Antibodies prepared in rabbits were purified by cross-immunoabsorption (
Nowack et al., 1976), and monospecificity was verified by immunofluorescence
radioimmunoassay and hemagglutination assays (Foidart et al., 1978; Yaoita et
al., ...
Curtis C. Harris, Benjamin F. Trump, Gary D. Stoner, 1980
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The Immunogenetics of Autoimmune Diseases
... anti-DNA populations constitute distinct elements of the same autoimmune
response at different steps of maturation, as if the progressive appearance of the
antigenic monospecificity paralleled the disappearance of idiotypic recurrence.
The selective pressure for monospecificity arises only when the somatically
selected self—nonself discrimination mechanism is required, and this is little
more than mere tinkering. Although RNA splicing maintains the triplet codon
reading ...
9
Molecular Analysis of B Lymphocyte Development and Activation
It has been argued that monospecificity prevents autoreactive B cells from
escaping to the periphery. However, it has recently been demonstrated that the
majority of initial specificities generated in the bone marrow are autoreactive and
that ...
Harinder Singh, Rudolf Grosschedl, 2006
10
New Concepts of Antiviral Therapy
5.3 PPKIs with twofold specificity for both, herpesviral and cellular protein kinases
The selectivity of PPKIs in antiviral activity is a crucial point of drug development
and in many cases the evidence for monospecificity of action is difficult to ...
Elke Bogner, Andreas Holzenburg, 2007
