KSIĄŻKI POWIĄZANE ZE SŁOWEM «ORTHOCAINE»
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1
Drug Discovery: A History
This was the first ever indication of useful local anaesthetic activity in synthetic
compounds that did not contain a benzoate ester function. 63 Einhorn
immediately sent one of his phenolic compounds, orthocaine, to Farbwerke
Hochst in 1896.
Some of these are described a s follows: (a) Orthocaine (Orthoform-New,
Orthoform), Chemically it is methyl m-amino-p-hydroxybenzoate. It is prepared by
esterifying p-hydroxybenzoic acid with methyl alcohol to yield the ester which on
...
C. Orthocaine BAN, 0=C— OCH Methyl 3-amino-4-hydroxybenzoate B.P. 1953
Synthesis : COOH COOH COOH HNO, H,S04 Sn/HCl . MeOH. p-Hydroxy-
benzoic acid p-Hydroxy-/«- nitro-benzoic acid p-Hydroxy-m- amino-benzoic acid
OH ...
4
Systematic Lab Experiments in Organic Chemistry
+ H,O NH, OH ethyl-p-aminobenzoate wn Orthocaine Esters, which are
derivatives of acids are usually prepared by the reaction of an alcohol and a
carboxylic acid in the presence of an acid catalyst usually sulphuric acid. This
reaction called ...
5
Unwanted Effects of Cosmetics and Drugs Used in Dermatology
... 695 orris root oil, 695 orris root powder, 695 orthocaine, 73 orthoform, new, 23,
74 orthoform, old, 23, 74 orthoform see orthocaine Oryza sativa under rice bran
wax, 696 oryzanol, 713 osirol see 3,7-dimethyl-7- methoxy-octan-2-ol oxacillin, ...
Anton C. de Groot, Johan Pieter Nater, J. Willem Weyland,
1994
6
The extra pharmacopoeia: incorporating Squire's "Companion".
A white or faintly yellow, odourless, tasteless, crystalline powder. M.p. 141° to
143°. Slightly soluble in water; soluble 1 in 7 of alcohol and I in 50 of ether;
readily soluble in solutions of alkali hydroxides. Orthocaine is a local anaesthetic
of the ...
William Martindale, Norman W. Blacow, Ainley Wade,
1972
7
The Extra Pharmacopoeia: "Amendments" ( 2 l.) inserted
A white or faintly yellow, odourless, tasteless, crystalline powder. Slightly soluble
in water; soluble 1 in 7 of alcohol and 1 in 50 of ether, readily soluble in sodium
hydroxide solution. Uses. Orthocaine is a local anaesthetic but owing to its ...
8
Dental materia medica, pharmacology and therapeutics
ORTHOCAINE Orthocaina [Orthocain.] B.P. "Ortho- form." The methyl ester of
aminohydroxybenzoic acid. HO.C,H,(NH2) COOCH,. BUTYL AMINOBENZOATE
Butylis Aminben- zoas [Butyl Aminobenz.] B.P. " Butesin." " Piano- form."
ACTIONS ...
Walter James Dilling, Samuel Hallam, Nancy V. Dilling,
1954
Wt. 167.1 Orthocaine is the methyl ester of m,amino,p,hydroxybenzoic acid. It
may be prepared by esterifying with methyl alcohol the reduction product of 3,
nitro,4,hydroxybenzoic acid. Description. A white, or faintly yellow, crystalline
powder ...
10
Concise Dictionary of Biomedicine and Molecular Biology
Orthocaine tmol wt I67l An anesthetic agem. Ortho-Cept A trade name for a
combination dmg comaining desogestrel and etbinyl estradiol used as a
comraceptive agem. Orthocheomatic Dye Any dye that stains cells with a single
color.