CO OZNACZA SŁOWO QUINOLONE
Quinolon
Kwinolony są rodziną syntetycznych szeroko rozpowszechnionych leków przeciwbakteryjnych. Pierwsze generowanie chinolonów zaczęło się od wprowadzenia kwasu nalidyksynowego w 1962 do leczenia infekcji dróg moczowych u ludzi. Kwas nalidyksynowy został wykryty przez George'a Leshera i współpracowników w destylacie podczas próby syntezy chlorochiny. Quinolony wywierają działanie antybakteryjne, zapobiegając zsiadaniu i duplikowaniu bakteryjnego DNA. Większość chinolonów w użyciu klinicznym należy do podfunkcjonalnego fluoroquinolonów, które zawierają atom fluoru przyłączony do centralnego układu pierścieniowego, zazwyczaj w pozycji 6 lub C-7.
Definicja słowa quinolone w słowniku
Definicja chinolonu w słowniku jest jedną z grupy syntetycznych antybiotyków, w tym cyprofloksacyny, które inaktywują enzym wymagany do replikacji pewnych mikroorganizmów.
KSIĄŻKI POWIĄZANE ZE SŁOWEM «QUINOLONE»
Poznaj użycie słowa
quinolone w następujących pozycjach bibliograficznych Książki powiązane ze słowem
quinolone oraz krótkie ich fragmenty w celu przedstawienia kontekstu użycia w literaturze.
1
Quinolone Antimicrobial Agents
An in-depth review of one of the most important classes of antimicrobial agents discovered in recent years. Compiles the current information on a larger number of compounds and their expanding clinical applications.
David C. Hooper, Ethan Rubinstein,
2003
2
Quinolone Antibacterials
This volume describes in detail the chemistry, mode of action and pharmacodynamics of the quinolones.
Jochen Kuhlmann, A. Dalhoff, H.-J. Zeiler,
2012
3
Quinolone Trafficking Via Outer Membrane Vesicles in ...
1.2.5 THE PSEUDOMONAS QUINOLONE SIGNAL P. aeruginosa produces a
third cell signaling molecule, 2-heptyl-3-hydroxy-4- quinolone termed the
Pseudomonas Quinolone Signal (PQS) (108). Unlike the typical HSLs, PQS is
unique to P.
Lauren Mashburn Warren,
2008
4
Drug Interactions in Infectious Diseases
Table 9.1 (continued) Mean % change Mean % change Quinolone Cation/
preparation/schedule in Cmax in AUC Reference Gati FeSO4/simultaneous with
quinolone −54a −35a [22] 2 h pre-quinolone −12 −10 2 h post-quinolone −3 −5 ...
Stephen C. Piscitelli, Keith A. Rodvold, Manjunath P. Pai,
2011
5
Antimicrobial Drug Resistance: Clinical and Epidemiological ...
Hence, quinolone resistance in Enterobacteriaceae may lead to treatment
failures and is a significant concern, as is the recent emergence of plasmid-
mediated resistance to quinolones. According to the 2004 NNIS report, means of
7.3% and ...
Quinolone antibiotics have potential to cause severe interactions with several
drugs (Table 4). As with macrolides, quinolones cause serious cardiac rhythm
problems in the presence of many other drugs. The macrolide-quinolone
combination ...
John Ide Ingle, Leif K. Bakland, J. Craig Baumgartner,
2008
7
Schiff's Diseases of the Liver
... sensitivity testing is advised. A fluoroquinolone is the therapy of choice for fully
sensitive or multidrug-resistant strains of Salmonella, while azithromycin or
ceftriaxone/cefotaxime should be used in quinolone-resistant strains [14].
Eugene R. Schiff, Willis C. Maddrey, Michael F. Sorrell,
2011
8
Antibacterial Chemotherapeutic Agents
7. Quinolone. antibacterials. 7.1 History and overview One of the most promising
and vigorously pursued areas of contemporary anti-infective chemotherapy is
that of the quinolone antibacterials. Broad spectrum, potent activity is available ...
9
Reviews of Environmental Contamination and Toxicology 192
... Macrolide Macrolide Macrolide Macrolide P-Lactam P-Lactam P-Lactam P-
Lactam P-Lactam Quinolone Quinolone Quinolone Quinolone Quinolone
Quinolone Quinolone Quinolone Quinolone Quinolone Compound Olaquindox
Olaquindox ...
In the first half of this chapter, an overview of the structural evolution of the
quinolone agents is presented, with emphasis on the modifications that have
provided advances in therapeutic utility. For ease of discussion, the examples
largely ...
Vincent T. Andriole,
2000
WIADOMOŚCI, KTÓRE ZAWIERAJĄ SŁOWO «QUINOLONE»
Sprawdź, o czym dyskutuje się w prasie krajowej i zagranicznej oraz jak jest stosowane słowo
quinolone w wiadomościach.
The Mysterious Origins of the Quinolones
The quinolone antibacterials have over fifty years of use in humans, although the first generation of them was not all that impressive. Most people either don't ... «Corante, Mar 15»
Southland Firefighter Says Popular Antibiotic Poisoned His Body …
“Doctors are not aware of the full range of toxicities that are associated with the quinolones,” said Charles Bennett, a professor of pharmacy at the University of ... «CBS Local, Mar 15»
Emergent BioSolutions Expands Biodefense Franchise; Acquires …
Most importantly, GC-072 shows activity not only on drug-sensitive strains, but also on those resistant to marketed antibiotics (including quinolones). It has a ... «GlobeNewswire, Gru 14»
Antibiotic Cousin Shows Promise in AML
Vosaroxin, an anticancer quinolone derivative, demonstrated improved overall survival and higher complete remission rates in AML patients with refractory ... «MedPage Today, Gru 14»
Quinolone Use During Pregnancy: Is It Safe?
Quinolones and fluoroquinolones are effective broad-spectrum antibiotics that are used to treat numerous infections; however, concerns about possible ... «Monthly Prescribing Reference, Lis 14»
Progress in the Development of Anti-malarial Quinolones
The quinolones are a promising class of compounds, with some demonstrating potent in vitro activity against the malaria parasite. This review summarizes the ... «Medscape, Lis 14»
Federal Court grants one of three prohibition applications for …
Claim Construction. The '114 Patent claims a novel class of quinolones distinguished by a fused pyrrolidine bicycle at the C-7 position of the quinolone ring. «Lexology, Cze 14»
Macrolide Benefit Unclear in Kids With Mycoplasma Pneumonia
... articles on observational and randomized trials comparing macrolide, tetracycline, or quinolone class antibiotics with spectrum of activity for M pneumonia with ... «Medscape, Maj 14»
TaiGen Biotechnology Receives Marketing Approval from the …
Taigexyn® is a new chemical entity (NCE), broad spectrum, non-fluorinated quinolone antibiotic available in both oral and intravenous formulations. TaiGen ... «PR Newswire, Mar 14»
Textile dyestuff concerns in Sweden
Three of the samples with quinolone traces were made of organic cotton and labelled with EU or Nordic eco-labels. Brett Mathews reports. Have you also seen? «Ecotextile News, Mar 14»