KSIĄŻKI POWIĄZANE ZE SŁOWEM «SHIVERER»
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The distribution of protein in the linear sucrose gradient also showed two peaks
in the shiverer compared to a single peak in the control (Mikoshiba et al., 1980b;
Bourre et al., 1980). The subcellular distribution of CNPase activity is altered ...
Russell E. Martenson, 1992
2
Molecular Genetics in Developmental Neurobiology
the proteins in the myelin rich fraction, four MBPs are clearly missing in the
shiverer (17, 18). The mutation is autosomally recessive and chimeric mice
analyses revealed that the humoral factors do not cause abnormalities and poor
myelin ...
3
Gene Expression in the Central Nervous System
myelin subcellular fractions from adult shiverer CNS (Mikoshiba et al., 1980a).
Primary abnormality in oligodendrocytes in shiverer mutant revealed by chimeric
analysis Chimera mice were produced by the aggregation of eight cell-stage ...
4
Strategy and Prospects in Neuroscience
Miura et al. tested whether the first exon is transcribed or further translated in
shiverer (31). By oligonucleotide directed site specific mutagenesis, Hindlll site
was introduced into the first exon of MBP cDNA, and anti-sense RNA was
prepared in ...
5
Functional Neurobiology of Aging
(1994) investigated the shiverer mouse, which shows central nervous system
abnormalities due to an autosomal-recessive deletion of a gene for myelin basic
protein. These mice show abnormalities in central myelin, but normal peripheral ...
Patrick R. Hof, Charles V. Mobbs, 2001
A—D. Immunohistochemical labeling against myelin basic protein (MBP) (green)
illustrating human—derived myelin in the shiverer spinal cord at different rostro (
A) caudal levels E—H. Immunohistochemical detection ofMBP (red), human ...
Helmut Kettenmann, Bruce R. Ransom, 2013
7
The Molecular Pathology of Autoimmune Diseases
A number of recent studies have used MBP-deficient (shiverer) mice to address
the issue of central tolerance to MBP. Neither Balb/c nor C3H mice can mount
proliferative responses to MBP and are resistant to MBP- induced EAE. However
...
Argyrios N Theofilopoulos, Constantin A. Bona, 2002
8
Diffusion MRI: From Quantitative Measurement to In vivo ...
7.4.1.1 Shiverer Mouse The shiverer mouse, in which the myelin basic protein (
Mbp) gene is mutated (Readhead and Hood, 1990), is so named because of its “
shaky” phenotype. In the CNS of the shiverer mutant mouse (see also Section ...
Heidi Johansen-Berg, Timothy E.J. Behrens, 2013
9
Advances in Multiple Sclerosis and Experimental ...
Similar observations within the CNS were made in the Shiverer mutant. In these
mice, expression of MBP is abrogated due to a deletion of the coding regions
downstream from the first exon [213], resulting in complete failure to ever form ...
10
Gliogenesis: Historical Perspectives, 1839 - 1985: ...
Compared to jimpy, the hypomyelination found in the mutant shiverer (shi) was
less severe. The shiverer mutation was of special interest because it produced a
known biochemical defect, an almost complete lack of MBP in the CNS and PNS
...
Henry Webster, Karl E. Åström, 2008
WIADOMOŚCI, KTÓRE ZAWIERAJĄ SŁOWO «SHIVERER»
Sprawdź, o czym dyskutuje się w prasie krajowej i zagranicznej oraz jak jest stosowane słowo
shiverer w wiadomościach.
Generation and isolation of oligodendrocyte progenitor cells from …
... and myelinate the shiverer mouse, and then by demonstrating that transplantation of hiPSC-derived PDGFR-α+ OPCs can rescue this hypomyelinated mouse. «Nature.com, Lip 15»
Shivers: the latest research [H&H VIP]
The most common clinical sign in shiverers is difficulty when the farrier is trimming or shoeing the hind feet (see box, right); other signs include muscle twitching, ... «Horse & Hound, Gru 14»
What was making the news 100 years ago this week
It was described as a “shiverer”; it was suffering from a disease of nervous affection of the spine. When it was put into harness it simply rocked and was liable to ... «Manchester Evening News, Lip 14»
Frozen to the bone
My fellow shiverer bites a giant chunk off her (now-empty) glass, just to see if she can. So far, this is the highlight of our night. Continue reading it below ... «Boston Globe, Mar 14»
Reigning champs hold lead at Bramham
He's not the most straightforward horse and has lots of problems, he suffers from ulcers, is stressy and a shiverer but all came good this weekend.” Pippa Funnell ... «Horsetalk, Cze 13»
Scary snaps: How to shoot frighteningly good photos this Halloween
Our eyes are accustomed to overhead light, like the sun, and any light source from underneath is an instant spine-shiverer. Concoct creepy compositions. «CNN, Paz 12»
Stem Cells Myelinate Human Brain
Using the shiverer mouse model, in which deletions of the myelin basic protein prevent myelination in the central nervous system, the scientists further showed ... «Scientist, Paz 12»
Sikeres kísérleti őssejtterápia idegrendszeri elváltozások kezelésére
... Neonatal chimerization with human glial progenitor cells can both remyelinate and rescue the otherwise lethally hypomyelinated shiverer mouse címmel. «Origo, Cze 08»
Human Stem Cells Cure Fatal Myelin Deficiency In Mice And Could …
Scientists in the US have used human cells that behave like stem cells to help "shiverer" mice grow myelin around their nerve fibres and thereby avoid an ... «Medical News Today, Cze 08»
Leukodystrophie: Stammzellen ersetzen Myelinscheiden
Die Injektion der Stammzellen beseitigte bei einigen Tieren das ständige Schwanken und Zittern (“Shiverer”) und steigerte deren Lebenserwartung. Einige Tiere ... «Deutsches Ärzteblatt, Cze 08»
