O QUE SIGNIFICA 암포테리신B EM COREANO
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definição de 암포테리신B no dicionário coreano
Anticófeno poliênico de anfotericina B. É inválido para bactérias, mas tem um amplo espectro de atividade antimicrobiana contra fungos. Atua alterando a permeabilidade das células da bactéria e vazando componentes intracelulares. Existe tolerância e existe resistência cruzada entre nistatina. Devido à fraca absorção do aparelho digestivo, é aplicado a infecções fúngicas intensas, como candidíase por injeção intravenosa. A aplicação local às infecções fúngicas superficiais também é eficaz. Efeitos secundários, reações irritáveis são grandes e causam rim ou flebite. 암포테리신B 폴리엔계 항생물질. 세균에는 무효인데, 진균에 대해서 넓은 항균스펙트럼을 지닌다. 균의 세포벽 투과성을 변화하고 세포내 성분을 누출시킴으로써 작용한다. 내성이 나타나고 니스타틴과의 사이에 교차내성이 있다. 소화관으로부터의 흡수가 나쁘기때문에 정맥내 주사에 의해 칸디다증 등의 심재성(深在性) 진균감염증에 적용된다. 표재성(表在性) 진균감염증에 국소적용해도 효과가 있다. 부작용, 과민성 반응이 크고 신장애나 정맥염 등을 일으킨다.
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10 LIVROS EM COREANO RELACIONADOS COM «암포테리신B»
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1
Small Animal Clinical Pharmacology - 187페이지
In addition to its fungicidal action, there is convincing evidence that amphotericin B has significant immunomodulatory effects, which may play an important role in its antifungal activity. The results of both in vitro and in vivo studies suggest that ...
Jill E. Maddison, Stephen W. Page, David Church (BVSc.), 2008
2
The Antimicrobial Drugs - 338페이지
Three lipid-based formulations of amphotericin B are available in the United States.” These preparations have reduced the toxicity of this drug toward humans while retaining its excellent antifungal action. Amphotericin B colloidal dispersion ...
Eric Michael Scholar, William B. Pratt, 2000
3
Current Therapy in Neurologic Disease - 1권 - 165페이지
These acute adverse events usually diminish with repeated amphotericin B administration. If an adverse event persists or is severe, pretreatment with diphenhydramine, acetaminophen, prochlorperazine, narcotics, and/or corticosteroids is ...
Richard Tidball Johnson, John W. Griffin, Justin C. McArthur, 2006
4
Drug Interactions in Infectious Diseases - 290페이지
Infusion-related adverse effects, although noxious to the patient, rarely affect the ability to use amphotericin B or other agents. In contrast to the infusion-related adverse effects, dose-dependent adverse effects often limit the use of amphotericin ...
Stephen C. Piscitelli, Keith A. Rodvold, 2007
5
Infections of the Central Nervous System - 702페이지
Because amphotericin B concentrations in the subarachnoid space after intravenous administration are so low, some clinicians have used intrathecal administration, via subcutaneous reservoirs or by direct injection into the cisternal or lumbar ...
W. Michael Scheld, Richard J. Whitley, Christina M. Marra, 2004
6
Clinical Infectious Diseases: A Practical Approach - 389페이지
Flucytosine was among the first of the orally available antifungal compounds to be developed in the amphotericin B era, and it remains an important antifungal agent when used in conjunction with amphotericin B. The development of the ...
7
Antimicrobial Drug Resistance: Mechanisms of Drug Resistance
While more than one hundred polyene antibiotics have been described, amphotericin B and nystatin are the two agents most commonly used to treat fungal and some protozoal infections in humans (see Fig. 1). Amphotericin B is active ...
8
Clinical Mycology - 35페이지
(Pseudallescheria boydii), Candida lusitaniae, Candida guilliermondii, Scopulariopsis species, and Fusarium species generally are considered intrinsically resistant to amphotericin B (Speeleveld et al, 1996; Patel, 1998). Acquired resistance ...
and Director in the Division of Infectious Diseases William E. Dismukes Professor and Vice-Chairman in the Department of Medicine, Department of Infectious Diseases both at University of Alabama School of Medicine at Birmingham Peter G. Pappas Professor of Medicine, Division of Infectious Diseases Wayne State University School of Medicine Jack D., 2003
9
Critical Care Medicine: Perioperative Management - 684페이지
The daily and total doses of amphotericin B depend on the severity of infection and the type of fungus as well as the patient's response. Although some clinicians suggestgradual increases in dose until therapeutic doses are reached over ...
Michael James Murray, 2002
10
Infectious Diseases - 318페이지
Amphotericin B has been the preferred agent for empiric therapy in the persistently febrile, neutropenic host (27,28), although recently, liposomal amphotericin B has been shown to have similar efficacy and increased tolerance when ...
Sherwood L. Gorbach, John G. Bartlett, Neil R. Blacklow, 2004
