与 «CALPAIN»相关的英语书籍
在以下的参考文献中发现
calpain的用法。与
calpain相关的书籍以及同一来源的简短摘要提供其在 英语文献中的使用情境。
1
Regulation of
Calpain-1 Signaling in Platelets
There has been considerable interest in elucidating the physiological function of calpains implicating them in a wide variety of cellular processes including cell motility, proliferation, apoptosis, cytoskeleton rearrangement, and ...
2
Calpain Methods and Protocols
annot be homogenized immediately, store tissue at -70°C to minimize m calpain
activation. Do not freeze sample in liquid nitrogen as this e sample and reduce
calpain activity. d brain samples, large amounts of protein (100-150 Jig) may be ...
3
Calpains: Pharmacology and Toxicology of a Cellular Protease
This new edition offers a clear and through examination of the most recent results of thirty years of research on calcium-activated-neutral protease (CANP or Calpain).
K K W Wang, Po-wai Yuen, 1999
4
Encyclopedia of Molecular Pharmacology
Calpains. Figure 1 Domain structures of calpain superfamily. Figure kindly
provided by Dr. Hiroyuki Sorimachi, Laboratory of Biological Function, University
of Tokyo, Japan. Examples of pathological conditions that have been associated
to the.
5
Handbook of Neurochemistry and Molecular Neurobiology: ...
An increase in the intracellular free Ca2+ level activates the Ca2+-dependent
cysteine protease calpain that can mediate neuronal death. Various studies
demonstrated that calpain could degrade key cellular substrates so as to impair ...
Abel Lajtha, Naren Banik, 2007
6
Cardiac Arrest: The Science and Practice of Resuscitation ...
calpain and m-calpain undergo N-terminal autoproteoly- sis at a [Ca2] slightly
greater than that required for substrate proteolysis. The result of autoproteolysis
is a decreased Ca2 requirement for subsequent proteolytic activity (0.6–0.8 M for
...
Norman A. Paradis, Henry R. Halperin, Karl B. Kern, 2007
In most reported cases, down-regulation is inhibited by calpain inhibitors
although this effect is not always seen2 '3 and inhibition is at best partial. The mM
calpain isoform (m-calpain) has been shown to cleave PKC more efficiently than
the ...
8
Protein Misfolding, Aggregation and Conformational Diseases: ...
Calpains, a class of Ca2-dependent cysteine proteases, were the obvious
candidates for that role. Skeletal muscles contain the ubiquitous m-calpain and -
calpain (activated at mM and M Ca2 concentration, respectively) and a muscle
specific ...
Vladimir N. Uversky, Anthony Fink, 2007
9
Indicators of Milk and Beef Quality
muscle fibres with μ-calpain resulted in thinner Z-lines and reduced fibre strength
, demonstrating that μ-calpain is capable of reducing the mechanical strength of
muscle fibres (Christensen et al., 2003). Recently a role of calpain 3 (i.e. p94) ...
J. F. Hocquette, S. Gigli, 2005
10
Comprehensive Toxicology
Multiple members of the caspase family have been shown to be cleaved directly
by calpain leading to their inactivation (Chua et al. 2000), suggesting an
important antiapoptotic role for calpain in the modulation and regulation of known
...
包含词语«CALPAIN»的新条目
找出国内和国际出版社所讨论的内容，以及词语
calpain在以下新条目的上下文中是如何使用的。
Hypoxia induces calpain activity and degrades SMAD2 to attenuate …
Under inflammatory conditions or during tumor progression macrophages acquire distinct phenotypes, with factors of the microenvironment ... «7thSpace Interactive, 七月 15»
The flavonoid beverage Haelan 951 induces growth arrest and …
A major challenge in pancreatic cancer treatment is the resistance of human pancreatic cancer cells to apoptosis. Soy isoflavones and calpain ... «7thSpace Interactive, 七月 15»
Genetic evidence in the mouse solidifies the calcium hypothesis of …
Calcium overload also promotes activation of the calcium-activated protease calpain, which has also been shown to contribute to the ... «Nature.com, 六月 15»
Perfect the art of smoking meat with the help of science
Just below 40 degrees is where an enzyme called calpain reaches peak productivity, while another called cathepsin produces the best results ... «Techly, 六月 15»
Tandem phosphorylation within an intrinsically disordered region …
Cleavage of ACTN4 by m-calpain, a protease that in motile cells is predominantly activated at the rear, removes the Tyr4 site. We found that introducing a ... «Science Magazine, 五月 15»
Authors Lien CY, Chuang TY, Hsu CH, Lin CL, Wang SE, Sheu SJ …
... Bcl-2-associated X protein, calpain, caspase 12, caspase 9, and caspase 3 were significantly suppressed in DOX-treated mice under oral ... «Dove Medical Press, 五月 15»
Early Passion for Science, Medicine Puts UK Grad on Fast Track to …
He worked with particular isoforms calpain 5 and 7, atypical calpains whose role in the nervous system are poorly understood. His projects ... «UKNow, 五月 15»
Gephyrin: a central GABAergic synapse organizer
Gephyrin was found to interact directly with and be subject to proteolysis by the Ca2+-dependent cysteine protease, calpain-1, suggesting that ... «Nature.com, 四月 15»
Consortium of LGMD Foundations Expands Free Diagnostic …
The consortium includes the Cecil B Day Family, Inc (LGMD2B), Coalition to Cure Calpain 3 (LGMD2A), Jain Foundation (LGMD2B), Kurt + ... «Business Wire, 三月 15»
Intracellular Calcium Affects Colon Cancer Cell Motility
... study “Modulation of Intracellular Calcium Levels by Calcium Lactate Affects Colon Cancer Cell Motility through Calcium-Dependent Calpain ... «Colon Cancer News Today, 二月 15»
