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1
The Principles of Clinical Cytogenetics
The dicentric recombinant is genetically unstable because each of the two
centromeres could potentially orient toward opposite poles of the dividing cell.
The material between the two centromeres would remain stretched between the
poles of ...
Steven Gersen, Martha B. Keagle, 2013
2
Technical Basis of Radiation Therapy: Practical Clinical ...
For simplicity, we will describe in detail the formation of a dicentric; similar
considerations apply to rings and anaphase bridges. The formation of a dicentric
is illustrated (Fig. 13.3). This aberration involves an interchange between two
separate ...
3
The Cell Cycle: Principles of Control
Non-reciprocal translocations can be particularly dangerous if they produce a
chromosome with two centromeres (a dicentric chromosome). In the next mitosis
the two centromeres of one sister chromatid could become attached to opposite ...
4
Checkpoint Controls and Cancer
Telomeric erosion and the generation of dicentric chromosomes and anaphase
bridges. As cells divide in the absence of telomerase, telomere shortening (A)
occurs, exposing the ends of the chromosomes. These ends are thought to be ...
5
Genetics Manual: Current Theory, Concepts, Terms
Inversion continued however both acentric fragments and dicentric chromosomes
besides the two parental ones. Four-strand double crossing over results in the
formation of two acentric fragments and two dicentric chromosomes and ...
6
ISCN 2013: An International System for Human Cytogenetic ...
It is apparent from the symbol and from the specification of the chromosome(s)
involved that the dicentric chromosome replaces one or two normal
chromosomes. There is no need to indicate the missing normal chromosome(s) (
cf., whole-arm ...
International Standing Committee on Human Cytogenetic Nomenclature, Lisa G. Shaffer, Jean McGowan-Jordan, 2013
7
Encyclopedia of Genetics, Genomics, Proteomics, and Informatics
Dicentric Ring Chromosomes Dicentric Chromosome: This has two centromeres.
It is usually an unstable structure because at anaphase the two centromeres are
pulled toward opposite poles and that generates a bridge that may be ruptured ...
8
Mammalian Chromosomes: Advances in Research and Application: ...
A new study, 'Telomere disruption results in non-random formation of de novo
dicentric chromosomes involving acrocentric human chromosomes,' is now
available. “Genome rearrangement often produces chromosomes with two
centromeres ...
9
Drosophila Cytogenetics Protocols
Dicentric chromosome formation results from exchange between two FRTs that
lie in an inverted relative orientation on the same chromosome arm of replicated
sister chromatids (see Fig. 1). The chromosomal material distal to the FRT sites is
...
10
Comparative Karyology of Primates
dicentrics for the short arms [dic(Yp)], while breakage and reunion of the short
arms lead to dicentrics for the long arms [dic(Yq)]. Formation of a stable dicentric
appears to depend on breakage and reunion close to the centromeric region.
Bruno Chiarelli, Ann L. Koen, Giuseppe Ardito, 1979
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Huron Digital Pathology Customizes Wide-Field TISSUEscope™ CF …
These chromosomes are referred to as dicentric chromosomes (DCs). Biodosimetry studies require specialist expertise and equipment, as well ... «News-Medical.net, 五月 15»
Automation of the cytokinesis-block micronucleus cytome assay by …
New developments in automated cytogenetic imaging: unattended scoring of dicentric chromosomes, micronuclei, single cell gel electrophoresis, and ... «BioTechniques.com, 十二月 14»
Just the FACTs about regulating CenH3 localization
Incorporation of CenH3 outside of centromeric chromosomes can lead to the formation of dicentric chromosomes and subsequent chromosome ... «Fred Hutchinson Cancer Research Center News, 十月 14»
Whoa! Report: ISIS recently threatened to kill James Foley and …
... was well aware of Foley's immediate peril. and yet partied on at the Vineyard. http://t.co/8BPzbycLUU. — beth (@dicentric) August 20, 2014. «Twitchy, 八月 14»
Inaugural Centromere Biology Gordon Conference: Beth Sullivan
This image is of an induced/engineered dicentric human chromosome (center of image) created in the Sullivan lab at Duke University. «PLoS Blogs, 七月 14»
Plant models for crop breeding of the future
... are relatively stable at mitosis and transmissible to the next generation, regardless of the centromere form (dicentric or monocentric). «Nanowerk, 六月 14»
Chromothripsis Event Touches off Development of Rare Form of …
Using FISH, they noted that the Robertsonian chromosome is dicentric. They said that during mitosis, mitotic spindles coming from opposite poles could attach to ... «GenomeWeb, 三月 14»
Biochip Device To Detect Dangerous Radiation In Our Bodies
Currently, in the absense of physical symptoms, which may not occur for several days, a blood test called a dicentric chromosome assay measures chromosomal ... «Inventorspot, 八月 13»
New biochip holds great promise for quickly triaging people after …
Currently, the most common way to measure radiation exposure is a blood assay called dicentric chromosome assay that tracks chromosomal ... «Phys.Org, 八月 13»
Do the creationist shuffle and twist!
The crossover strands are totally screwed up. One is now dicentric, having two centromeres — when they're separated at cell division, it will be ... «ScienceBlogs, 六月 13»
