10 BÜCHER, DIE MIT «SUBTILISIN» IM ZUSAMMENHANG STEHEN
Entdecke den Gebrauch von
subtilisin in der folgenden bibliographischen Auswahl. Bücher, die mit
subtilisin im Zusammenhang stehen und kurze Auszüge derselben, um seinen Gebrauch in der Literatur kontextbezogen darzustellen.
1
Springer Handbook of Enzymes
subtilisin BL <5> [24] subtilisin DY <1,2,4> [3,28,41,42] subtilisin E subtilisin GX
subtilisin S41 subtilisin Sendai subtilisin amylosacchariticus <1,2,4> (from
Bacillus subtilis var. amylosac- chariticus) [1,5] subtilisin J <7> [54]
subtilopeptidase ...
Dietmar Schomburg, Ida Schomburg, Antje Chang, 2002
On the substrate succinyl-Ala-Ala-Pro-Phe-pnitroanilide (sAAPFpNA) for example
, the value of kw, which measures rates of substrate tumover, is ten times higher
for subtilisin Carlsberg. The value of Km, the overall affinity for binding substrate,
...
Jan H. van Ee, Onno Misset, 1997
3
Industrial Enzymes: Structure, Function and Applications
It had been observed earlier that the subtilisin BPN' structure is very tolerant of
single mutations, and this tolerance may have been necessary for survival of the
enzyme during the course of evolution. This structural tolerance is not surprising
if ...
Julio Polaina, Andrew P. MacCabe, 2007
4
Clinical Contact Lens Practice
Another group of enzymatic cleaners uses subtilisin, an enzyme derived from the
bacterial fermentation of Bacillus licheniformis (6,78). One of the cleaners is
ReNu Enzymatic tablets (Bausch & Lomb), which have been available in several
...
Edward S. Bennett, Barry A. Weissman, 2005
5
Food Enzymes: Structure and Mechanism
The scope of this discussion will be limited to subtilisin, which has gained
considerable importance due to the recent advent in recombinant DNA
technology (Wells and Estell 1988). Unlike trypsin and chymotrypsin, which are
mammalian ...
6
Enzymatic Reaction Mechanisms
O C6H5 'X' ' HF F s—CH2 I | | O O\ _L' O—S—CH2 || 1 C Ho \ \ clH2 'v cHZ
Subtilisin Subtilisin o C6H5 o\\C /CH3 0_5|“CH2 | 0 H0 H20 0 /SH \\c /CH3 HZC | |
,s Subtilisin HZC | THIOLSUBTILISIN Subtilisin Fig. 6-6. Chemical mutagenesis of
...
Perry A. Frey, Adrian D. Hegeman, 2007
7
Hydrolysis: Peptide Bonds
By comparison chymotrypsin was 50 times more active on benzoyl-L-tyrosine
ethyl ester than subtilisin Carlsberg. Glazer (39) , Barel and Glazer (Jfi) , and
Myers and Glazer (87) have determined kinetic parameters for the hydrolysis of a
...
8
Enzymes in Action Green Solutions for Chemical Problems: ...
conventional medium would be beneficial in obtaining a viable enzyme-polymer
system for utility in organic media [139]. To examine their hypothesis they
synthesized subtilisin-containing polyacrylate in toluene. Subtilisin was modified
with ...
B. Zwanenburg, Marian Mikołajczyk, Piotr Kiełbasiński, 2000
9
Non-peptide Inhibitors of Proprotein Convertase
Subtilisin ...
The Cad—dependent mammalian Proprotein convertase subtilisin Kexins (
PCSKs) or Propro— tein/Prohormone Convertases (PCs) are a family of
endoproteases that play critical roles not only in normal development and
metabolism but also ...
Utpal Chandra De, Ajoy Basak, 2012
10
Biotechnology and Bioengineering
CLECs of subtilisin have been described; these were active and very stable in
both aqueous and organic media and could perform peptide synthesis,
transesterifications and enantio- and regio-selective reactions (Wang et al., 1997;
Haring et ...
10 NACHRICHTEN, IN DENEN DER BEGRIFF «SUBTILISIN» VORKOMMT
Erfahre, worüber man in den einheimischen und internationalen Medien spricht und wie der Begriff
subtilisin im Kontext der folgenden Nachrichten gebraucht wird.
FDA approves Praluent to treat certain patients with high cholesterol
... injection, the first cholesterol-lowering treatment approved in a new class of drugs known as proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitors. «FDA.gov, Jul 15»
FDA Panel Advises Praluent PCKS9 Inhibitor Approval
At separate advisory meetings, FDA officials voted in favor of approval for 2 proposed proprotein convertase subtilisin kexin 9 (PCKS9) inhibitors for lowering ... «Pharmacy Times, Jun 15»
5 things to know about cholesterol-lowering PCSK9 inhibitors
Dr GleasonThis summer the first 2 drugs in a new class of cholesterol-lowering medications, called PCSK9 (proprotein convertase subtilisin/kexin type 9) ... «ModernMedicine, Jun 15»
FDA Advisory Committee Recommends Approval Of Alirocumab …
If approved by the FDA, Praluent is expected to be the first fully human monoclonal antibody targeting PCSK9 (proprotein convertase subtilisin/kexin type 9) in ... «Science 2.0, Jun 15»
In-Depth Analysis of Amgen Cholesterol Drug Favored by FDA Panel
The circulating protein proprotein convertase subtilisin/kexin type 9 (PCSK9) was initially considered a drug target due to literature reports of mutant individuals ... «Pharmacy Times, Jun 15»
Research and Markets: A Competitive Analysis of the Global Acute …
The key drug targets include the proprotein convertase subtilisin/kexin type 9 (PCSK9) and cholesteryl ester transfer protein (CETP). GSK has so far recruited ... «Business Wire, Jun 15»
High Cholesterol PCSK9 Drugs Could be Next To Bust Budgets …
Prime's internal analysis finds PCSK9 inhibitors (Proprotein Convertase Subtilisin/Kexin type 9) could add between $0.93 and $6.71 per member per month ... «PR Newswire, Jun 15»
After-Hours Stock Movers 06/09: (REGN) (CTIC) (SIGM) HIGHER …
... (NASDAQ: REGN) INDICATED HIGHER (halted); Regeneron (NASDAQ: REGN) and Sanofi (NYSE: SNY) PCSK9 (proprotein convertase subtilisin/kexin type ... «StreetInsider.com, Jun 15»
EMA Committee Recommends Approval of Evolocumab
LONDON, UK — Evolocumab (Repatha, Amgen), an investigational human monoclonal antibody for proprotein convertase subtilisin-kexin type 9 (PCSK9), ... «Medscape, Mai 15»
Investment Analysts' Recent Ratings Changes for Regeneron …
An upcoming pipeline catalyst for Regeneron includes a regulatory decision on the company's PCSK9 (proprotein convertase subtilisin/kexin type 9) antibody, ... «Dakota Financial News, Mai 15»
