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Meaning of "cyclosporine" in the English dictionary

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DICTIONARY
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PRONUNCIATION OF CYCLOSPORINE

cyclosporine  [ˌsaɪkləˈspɔːriːn] play
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GRAMMATICAL CATEGORY OF CYCLOSPORINE

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Cyclosporine is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES CYCLOSPORINE MEAN IN ENGLISH?

Ciclosporin

Ciclosporin ; cyclosporine; cyclosporin; or ciclosporin A, cyclosporine A, or cyclosporin A is an immunosuppressant drug widely used in organ transplantation to prevent rejection. It reduces the activity of the immune system by interfering with the activity and growth of T cells. It was initially isolated from the fungus Tolypocladium inflatum, found in a soil sample obtained in 1969 from Hardangervidda, Norway, by Hans Peter Frey, a Sandoz biologist. Most peptides are synthesized by ribosomes, but ciclosporin is a cyclic nonribosomal peptide of 11 amino acids and contains a single D-amino acid, which are rarely encountered in nature.

WORDS THAT RHYME WITH CYCLOSPORINE


boreen
ˈboːriːn
chlorine
ˈklɔːriːn
chorine
ˈkɔːriːn
euchlorine
juːˈklɔːriːn
evergreen
ˈɛvəˌɡriːn
figurine
ˌfɪɡəˈriːn
green
ɡriːn
Greene
ɡriːn
helleborine
ˌhɛlɪˈbɔːriːn
marine
məˈriːn
on-screen
ˌɒnˈskriːn
organochlorine
ˌɔːɡənəʊˈklɔːriːn
screen
skriːn
serene
sɪˈriːn
submarine
ˈsʌbməˌriːn
sunscreen
ˈsʌnˌskriːn
tangerine
ˌtændʒəˈriːn
vitrine
ˈvɪtriːn
widescreen
ˈwaɪdˌskriːn
wolverine
ˈwʊlvəˌriːn

WORDS THAT BEGIN LIKE CYCLOSPORINE

cycloplegic
cyclopropane
cyclops
cyclorama
cycloramic
cycloserine
cycloses
cyclosis
cyclospermous
cyclosporin
cyclostomate
cyclostomatous
cyclostome
cyclostomous
cyclostyle
cyclostyled
cyclothyme
cyclothymia
cyclothymiac
cyclothymic

WORDS THAT END LIKE CYCLOSPORINE

aquamarine
brine
Catherine
chondrophorine
doctrine
endocrine
exocrine
fluorine
Katharine
Katherine
leporine
margarine
murine
poitrine
shrine
signorine
trine
urine
uterine
victorine

Synonyms and antonyms of cyclosporine in the English dictionary of synonyms

SYNONYMS

Translation of «cyclosporine» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF CYCLOSPORINE

Find out the translation of cyclosporine to 25 languages with our English multilingual translator.
The translations of cyclosporine from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «cyclosporine» in English.

Translator English - Chinese

环孢素
1,325 millions of speakers

Translator English - Spanish

ciclosporina
570 millions of speakers

English

cyclosporine
510 millions of speakers

Translator English - Hindi

साइक्लोस्पोरिन
380 millions of speakers
ar

Translator English - Arabic

السيكلوسبورين
280 millions of speakers

Translator English - Russian

циклоспорин
278 millions of speakers

Translator English - Portuguese

ciclosporina
270 millions of speakers

Translator English - Bengali

cyclosporine
260 millions of speakers

Translator English - French

cyclosporine
220 millions of speakers

Translator English - Malay

Cyclosporine
190 millions of speakers

Translator English - German

Cyclosporin
180 millions of speakers

Translator English - Japanese

シクロスポリン
130 millions of speakers

Translator English - Korean

사이클로스포린
85 millions of speakers

Translator English - Javanese

Cyclosporine
85 millions of speakers
vi

Translator English - Vietnamese

cyclosporine
80 millions of speakers

Translator English - Tamil

சைக்ளோஸ்போரின்
75 millions of speakers

Translator English - Marathi

सायक्लोस्पोरिन
75 millions of speakers

Translator English - Turkish

siklosporin
70 millions of speakers

Translator English - Italian

ciclosporina
65 millions of speakers

Translator English - Polish

cyklosporyna
50 millions of speakers

Translator English - Ukrainian

циклоспорин
40 millions of speakers

Translator English - Romanian

ciclosporina
30 millions of speakers
el

Translator English - Greek

κυκλοσπορίνη
15 millions of speakers
af

Translator English - Afrikaans

siklosporien
14 millions of speakers
sv

Translator English - Swedish

cyklosporin
10 millions of speakers
no

Translator English - Norwegian

ciklosporin
5 millions of speakers

Trends of use of cyclosporine

TRENDS

TENDENCIES OF USE OF THE TERM «CYCLOSPORINE»

The term «cyclosporine» is regularly used and occupies the 71.277 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Regularly used
67
/100
The map shown above gives the frequency of use of the term «cyclosporine» in the different countries.
Principal search tendencies and common uses of cyclosporine
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «cyclosporine».

FREQUENCY OF USE OF THE TERM «CYCLOSPORINE» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «cyclosporine» during the past 500 years. Its implementation is based on analysing how often the term «cyclosporine» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about cyclosporine

EXAMPLES

10 ENGLISH BOOKS RELATING TO «CYCLOSPORINE»

Discover the use of cyclosporine in the following bibliographical selection. Books relating to cyclosporine and brief extracts from same to provide context of its use in English literature.
1
Textbook of Small Animal Surgery
whole-blood concentrations of cyclosporine (approximately 500 ng/mL). Neoral appears to be a more effective immunosuppressant than Sandimmune owing to a more complete absorption that results in a more sustained and predictable ...
Douglas H. Slatter, 2003
2
Advanced Therapy of Inflammatory Bowel Disease
Cyclosporine inhibits cellular immunity by interrupting the production of interleukin-1 (IL-1) and two receptors by helper T lymphocytes. Cyclosporine does not alter the function of granulocytes, monocytes, or macrophages but does alter B-cell ...
Theodore M. Bayless, Stephen B. Hanauer, 2001
3
Principles of Clinical Pharmacology
HPLC/UV methods for cyclosporine analyses use whole blood samples with cyclosporine D added as an internal standard [15, 16]. Patient blood samples are diluted with a solution of the internal standard in organic solvents to effect cell lysis, ...
Arthur J. Atkinson, Jr., Shiew-Mei Huang, Juan J.L. Lertora, 2012
4
Psychiatric Side Effects of Prescription and ...
These are the most frequent sites of cyclosporine A- related structural changes ( Trzepacz et al. 1995). An interesting and perhaps not uncommon cause of abnormal cyclosporine A levels is the failure to take the medication properly. This may ...
Thomas Markham Brown, Alan Stoudemire, 1998
5
Immunopharmacology
Specific immunosuppressive therapy has its origin in the 1970s when cyclosporine was discovered by J.F. Borel in 1976. The drug was originally considered as an antifungal compound but its immunoregulatory activities were learned rapidly.
Manzoor M. Khan, 2008
6
Inflammatory Bowel Disease: From Bench to Bedside
Cyclosporine and tacrolimus (FK 506) Chemistry and mechanism of action Cyclosporine is a cyclic polypeptide of fungal origin, and tacrolimus is a macrolide antibiotic. Although these entities are chemically unrelated their mechanisms of ...
Stephan R. Targan, Fergus Shanahan, Loren C. Karp, 2007
7
Management of Complications in Refractive Surgery: With 44 ...
5.1.5.1.3 Topical Cyclosporine A Cyclosporine A 0.05% ophthalmic solution ( Restasis) has been successfully used for the management of dry eye and has found increasing acceptance among refractive surgeons for optimizing the ocular  ...
Jorge L. Alió y Sanz, Dimitri T. Azar, 2008
8
Mechanism of Hepatitis C Virus Inhibition by the ...
25 Fig. 3.1 NS5A confers cyclosporine A resistance 37 Fig. 3.2 Cyclosporine A sensitivities of different Con 1bN 3s replicons 39 Fig. 3.3 Wildtype and mutant NS5A's did not differ in binding NS5B 39 Fig. 3.4 NS5A binds cyclophilin B 40 Fig .
Fiona J. Fernandes, 2008
9
Adult and Pediatric Urology
Despite the marked improvements seen and broad experience gained with cyclosporine, difficulties with its use continue to be encountered. Diminished bioavailability, especially in the immediate posttransplant period, and variable patient ...
Jay Young Gillenwater, 2002
10
Kidney and Pancreas Transplantation: A Practical Guide
Patients in the low-dose cyclosporine and cyclosporine withdrawal arms received IL-2 receptor blockade (daclizumab) induction to provide protection against acute rejection. The primary endpoint was measured GFR at 12 months and was not ...
T. R. Srinivas, Daniel A. Shoskes, 2010

10 NEWS ITEMS WHICH INCLUDE THE TERM «CYCLOSPORINE»

Find out what the national and international press are talking about and how the term cyclosporine is used in the context of the following news items.
1
Allergan Snaps Up Early-Stage Device Developer Oculeve
However, because cyclosporine takes up to six months to take effect, many patients stop administering drops earlier than necessary. Dry eye ... «Med Device Online, Jul 15»
2
Former Syracuse football DB signee Lamar Dawson hopes to earn …
He was forced to defer his enrollment to January 2015 and ultimately June 2015 as he healed, was weaned off his medicine, cyclosporine, and ... «Syracuse.com, Jul 15»
3
Allogeneic hematopoietic cell transplantation after failed autologous …
Post-grafting immunosuppression consisted of cyclosporine and mycophenolate mofetil. For patients with HLA-identical sibling donors, ... «Nature.com, Jul 15»
4
Ferroptosis in p53-dependent oncosuppression and organismal …
However, the authors did not test whether cyclosporine A, an inhibitor of mitochondrial permeability transition (MPT)-dependent regulated necrosis (a major, ... «Nature.com, Jul 15»
5
Breath of life
1983: First successful single-lung transplant is performed by the Toronto Lung Transplant Group; Cyclosporine, the first drug that effectively ... «OCRegister, Jul 15»
6
Two-Drug Combo Aims to Restore Insulin Production in Diabetes
The protocol combines two already-available generic oral drugs, the immunosuppressant cyclosporine and the proton-pump inhibitor ... «Medscape, Jul 15»
7
Pfizer Announces FDA Acceptance for Review of New Drug …
Use of XELJANZ in combination with biologic DMARDs or potent immunosuppressants, such as azathioprine and cyclosporine is not ... «MarketWatch, Jul 15»
8
Psoriatic Arthritis Pharmacotherapy Market Segment Forecasts up to …
While immunosuppressant helps to control the immune system including azathioprine and cyclosporine. TNF-α inhibitors assist reducing pain, ... «CSO Australia, Jul 15»
9
'God was looking out for me,' says Florida heart-transplant recipient
Then, in 1983 the Food and Drug Administration approved a new drug, cyclosporine, that could help the body's immune system fight infections ... «Orlando Sentinel, Jun 15»
10
mTOR inhibitor versus mycophenolic acid as the primary …
... calcineurin inhibitor, CNI, ciclosporin/cyclosporine, Neoral, Sandimmune, CsA, tacrolimus, Prograf, FK506 and kidney/renal transplantation. «BMC Blogs Network, Jun 15»

REFERENCE
« EDUCALINGO. Cyclosporine [online]. Available <https://educalingo.com/en/dic-en/cyclosporine>. May 2024 ».
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