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Meaning of "heteroduplex" in the English dictionary

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DICTIONARY
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PRONUNCIATION OF HETERODUPLEX

heteroduplex  [ˌhetərəʊˈdjuːpleks] play
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GRAMMATICAL CATEGORY OF HETERODUPLEX

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Heteroduplex is an adjective.
The adjective is the word that accompanies the noun to determine or qualify it.

WHAT DOES HETERODUPLEX MEAN IN ENGLISH?

Heteroduplex

A heteroduplex is a double-stranded molecule of nucleic acid originated through the genetic recombination of single complementary strands derived from different sources, such as from different homologous chromosomes or even from different organisms. One such example is the heteroduplex DNA strand formed in hybridization processes, usually for biochemistry-based phylogenetical analyses. Another example is the heteroduplexes formed when non-natural analogs of nucleic acids are used to bind with nucleic acids; these heteroduplexes result from performing antisense techniques using single-stranded peptide nucleic acid, 2'-O-methyl phosphorothioate or Morpholino oligos to bind with RNA. In meiosis, the process of crossing-over occurs between non-sister chromatids, which results in new allelic combinations of a population. In crossing-over, a Spo11 enzyme makes staggered nicks in a pair of sister chromatid strands. Subsequent enzymes trim back the 5' ends of the strand and a protein complex binds to the 3' single-stranded ends. Rad51 protein is recruited and binds in a protein complex to search for a complementary sequence analogous to double-strand-break repair.

Definition of heteroduplex in the English dictionary

The definition of heteroduplex in the dictionary is having polynucleotide strands derived from two different sources.

WORDS THAT RHYME WITH HETERODUPLEX


apoplex
ˈæpəˌpleks
card-index
ˈkɑːdˌɪndeks
carnifex
ˈkɑːnɪˌfeks
decomplex
ˈdiːkɒmpleks
diplex
ˈdaɪpleks
dorsiflex
ˈdɔːsɪˌfleks
fedex
ˈfedˌeks
frutex
ˈfruːteks
homosex
ˌhəʊməʊˈseks
hypercomplex
ˌhaɪpəˈkɒmpleks
immunocomplex
ˈɪmjʊnəʊˌkɒmpleks
Lastex
ˈlasteks
metroplex
ˈmetrəʊˌpleks
plex
pleks
prex
preks
silvex
ˈsɪlveks
sorex
ˈsɔːreks
tippex
ˈtɪpeks
vibex
ˈvaɪbeks
zex
zeks

WORDS THAT BEGIN LIKE HETERODUPLEX

heterocont
heterocycle
heterocyclic
heterocyst
heterocystous
heterodactyl
heterodactylous
heterodont
heterodox
heterodoxy
heterodyne
heteroecious
heteroecism
heteroflexible
heterogamete
heterogametic
heterogamety
heterogamous
heterogamy
heterogeneity

WORDS THAT END LIKE HETERODUPLEX

apartment complex
B complex
cinema complex
Cineplex
complex
duplex
fourplex
herpes simplex
immune complex
leisure complex
military-industrial complex
multiplex
octuplex
Oedipus complex
quadruplex
shopping complex
simplex
suplex
time-division multiplex
triplex

Synonyms and antonyms of heteroduplex in the English dictionary of synonyms

SYNONYMS

Translation of «heteroduplex» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF HETERODUPLEX

Find out the translation of heteroduplex to 25 languages with our English multilingual translator.
The translations of heteroduplex from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «heteroduplex» in English.

Translator English - Chinese

1,325 millions of speakers

Translator English - Spanish

heterodúplex
570 millions of speakers

English

heteroduplex
510 millions of speakers

Translator English - Hindi

heteroduplex
380 millions of speakers
ar

Translator English - Arabic

مضاعف متغاير
280 millions of speakers

Translator English - Russian

гетеродуплексный
278 millions of speakers

Translator English - Portuguese

heterod�lex
270 millions of speakers

Translator English - Bengali

heteroduplex
260 millions of speakers

Translator English - French

hétéroduplex
220 millions of speakers

Translator English - Malay

Heteroduplex
190 millions of speakers

Translator English - German

Hetero
180 millions of speakers

Translator English - Japanese

ヘテロ2本鎖
130 millions of speakers

Translator English - Korean

heteroduplex를
85 millions of speakers

Translator English - Javanese

Heteroduplex
85 millions of speakers
vi

Translator English - Vietnamese

heteroduplex
80 millions of speakers

Translator English - Tamil

heteroduplex
75 millions of speakers

Translator English - Marathi

हेटरोडुप्लेक्स
75 millions of speakers

Translator English - Turkish

heterodupleks
70 millions of speakers

Translator English - Italian

heteroduplex
65 millions of speakers

Translator English - Polish

heterodupleksu
50 millions of speakers

Translator English - Ukrainian

гетеродуплексний
40 millions of speakers

Translator English - Romanian

heteroduplex
30 millions of speakers
el

Translator English - Greek

ετεροδίκλωνο
15 millions of speakers
af

Translator English - Afrikaans

heteroduplex
14 millions of speakers
sv

Translator English - Swedish

heteroduplex
10 millions of speakers
no

Translator English - Norwegian

heterodupleks
5 millions of speakers

Trends of use of heteroduplex

TRENDS

TENDENCIES OF USE OF THE TERM «HETERODUPLEX»

The term «heteroduplex» is regularly used and occupies the 104.163 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Regularly used
52
/100
The map shown above gives the frequency of use of the term «heteroduplex» in the different countries.
Principal search tendencies and common uses of heteroduplex
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «heteroduplex».

FREQUENCY OF USE OF THE TERM «HETERODUPLEX» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «heteroduplex» during the past 500 years. Its implementation is based on analysing how often the term «heteroduplex» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about heteroduplex

EXAMPLES

10 ENGLISH BOOKS RELATING TO «HETERODUPLEX»

Discover the use of heteroduplex in the following bibliographical selection. Books relating to heteroduplex and brief extracts from same to provide context of its use in English literature.
1
Molecular Biology: Genes to Proteins
Nicking and strand exchange Symmetric heteroduplex Asymmetric heteroduplex FIGURE 13.11 Symmetric versus asymmetric heteroduplex DNA. Heteroduplex DNA that is present on the same region of two chromatids is called symmetric ...
Burton E. Tropp, 2012
2
Molecular Biology and Biotechnology: A Comprehensive Desk ...
The displaced strand then invades the homologous sequence of a nonsister chromatid and by strand exchange forms heteroduplex on one duplex with the displaced single strand, making a structure called a D-loop. The D-loop is then ...
Robert A. Meyers, 1995
3
Links Between Recombination and Replication: Vital Roles of ...
This might be carried out by at least two levels of reversibility in the heteroduplex joint formation by RecA. A heteroduplex joint, with a limited length formed through the primary contact, is likely to be reversible and would be dissociated unless ...
Proceedings of the National Academy of Sciences, 2002
4
PCR Strategies
Here we describe the use of a new method for genetic screening, referred to as heteroduplex mobility analysis or HMA (Delwart et al., 1993), which not only can distinguish between individual strains but can also provide reliable inferences of  ...
Michael A. Innis, David H. Gelfand, John J. Sninsky, 1995
5
Single Nucleotide Polymorphisms: Methods and Protocols
During each cycle of PCR, amplified DNA molecules undergo denaturation and renaturation and generate homoduplex as well as heteroduplex molecules. However as the molar concentration of the amplified products increase in the later ...
Pui-Yan Kwok, 2003
6
Childhood Leukemias
Heteroduplex analysis was originally designed for mutation detection in genetic diseases but, after modification, can also be applied to analysis of I G/ TCR PCR products. In heteroduplex analysis, PCR products are denatured (940 C) and ...
Ching-Hon Pui, 2012
7
Pharmacogenomics: Methods and Applications
To create homoduplex and heteroduplex molecules, the polymerase chain reaction (PCR) fragments are denatured followed by gradual reannealing such that in the presence of a heterozygous sequence change, “wild-type” and “mutant ” ...
Federico Innocenti, 2005
8
Molecular and Functional Models in Neuropsychiatry
4 Heteroduplex formation and detection of ENU-induced point mutations. (a) All the G1 mice heterozygously carry the ENU-induced mutation. The PCR amplification of the target sequence faithfully replicates the maternal and paternal  ...
Jim J. Hagan, 2011
9
Molecular Diagnostics: For the Clinical Laboratorian
HETERODUPLEX ANALYSIS IN MUTATION DETECTION Heteroduplex formation is required for many mutation scanning methods. Heteroduplex analysis (HA) refers to the technique based on the electrophoretic resolution of wild-type ...
William B. Coleman, Gregory J. Tsongalis, 2007
10
Genetics
The formation of heteroduplex DNA generates a D-loop, which is extended by repair synthesis, to cover the entire length of the gap. The extended single strand anneals with complementary sequence at the end, so that heteroduplex DNA ...
Prof. P.K. Gupta, 1988

8 NEWS ITEMS WHICH INCLUDE THE TERM «HETERODUPLEX»

Find out what the national and international press are talking about and how the term heteroduplex is used in the context of the following news items.
1
Diverse Pathways to Drug Targets
... indicated that miravirsen sequesters the liver-specific microRNA miR-122 in a highly stable heteroduplex, thereby inhibiting its function. «Genetic Engineering & Biotechnology News, Apr 15»
2
Improved transposon-based library preparation for the Ion Torrent …
When such a heteroduplex serves as a template during amplification onto a bead, the bead becomes populated by two different clones and will later be ... «BioTechniques.com, Apr 15»
3
Makrigiorgos Lab at Dana-Farber Publishes Proof of Concept for …
... of the fact that in some cases preferential amplification of mutant DNA is so great that it obviates the need to form a mutant-wildtype heteroduplex DNA. «GenomeWeb, Apr 14»
4
Inactivation of an integrated antibiotic resistance gene in …
The mix was incubated at 95°C for 15 min, 65°C for 30 min, room temperature for 30 min, and on ice for 30 min to form heteroduplex DNA. Following the ... «BioTechniques.com, Apr 14»
5
A method for high-throughput PCR-based genotyping of larval …
It is worth noting that the presence of bands running higher than 412 bp in lanes 2, 3, 4, 6, and 8 indicate DNA heteroduplex formation between mutant and wild ... «BioTechniques.com, Dec 13»
6
Does the Myriad Decision Presage a Golden Age of Patent-Free …
... SEQ ID NO:1, wherein a germline alteration is detected by forming a heteroduplex consisting of a first strand of nucleic acid selected from the ... «Patent Docs, Jun 13»
7
Generation of DNA nanocircles containing mismatched bases
... at 37°C. For MutS-DNA complexes, 9 ng 505-bp homoduplex circle, 9 ng 1100-bp heteroduplex circle, and 4 nM MutS were incubated at room temperature for ... «BioTechniques.com, Oct 11»
8
Formation and branch migration of Holliday junctions mediated by …
... Kmiec, E. B. & Holloman, W. K. Heteroduplex formation and polarity ... P. & West, S. C. Heteroduplex formation by human Rad51 protein: ... «Nature.com, Feb 08»

REFERENCE
« EDUCALINGO. Heteroduplex [online]. Available <https://educalingo.com/en/dic-en/heteroduplex>. May 2024 ».
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