10 ENGLISH BOOKS RELATING TO «HETERODUPLEX»
Discover the use of
heteroduplex in the following bibliographical selection. Books relating to
heteroduplex and brief extracts from same to provide context of its use in English literature.
1
Molecular Biology: Genes to Proteins
Nicking and strand exchange Symmetric heteroduplex Asymmetric heteroduplex
FIGURE 13.11 Symmetric versus asymmetric heteroduplex DNA. Heteroduplex
DNA that is present on the same region of two chromatids is called symmetric ...
2
Molecular Biology and Biotechnology: A Comprehensive Desk ...
The displaced strand then invades the homologous sequence of a nonsister
chromatid and by strand exchange forms heteroduplex on one duplex with the
displaced single strand, making a structure called a D-loop. The D-loop is then ...
3
Links Between Recombination and Replication: Vital Roles of ...
This might be carried out by at least two levels of reversibility in the heteroduplex
joint formation by RecA. A heteroduplex joint, with a limited length formed
through the primary contact, is likely to be reversible and would be dissociated
unless ...
Proceedings of the National Academy of Sciences, 2002
Here we describe the use of a new method for genetic screening, referred to as
heteroduplex mobility analysis or HMA (Delwart et al., 1993), which not only can
distinguish between individual strains but can also provide reliable inferences of
...
Michael A. Innis, David H. Gelfand, John J. Sninsky, 1995
5
Single Nucleotide Polymorphisms: Methods and Protocols
During each cycle of PCR, amplified DNA molecules undergo denaturation and
renaturation and generate homoduplex as well as heteroduplex molecules.
However as the molar concentration of the amplified products increase in the
later ...
Heteroduplex analysis was originally designed for mutation detection in genetic
diseases but, after modification, can also be applied to analysis of I G/ TCR PCR
products. In heteroduplex analysis, PCR products are denatured (940 C) and ...
7
Pharmacogenomics: Methods and Applications
To create homoduplex and heteroduplex molecules, the polymerase chain
reaction (PCR) fragments are denatured followed by gradual reannealing such
that in the presence of a heterozygous sequence change, “wild-type” and “mutant
” ...
8
Molecular and Functional Models in Neuropsychiatry
4 Heteroduplex formation and detection of ENU-induced point mutations. (a) All
the G1 mice heterozygously carry the ENU-induced mutation. The PCR
amplification of the target sequence faithfully replicates the maternal and paternal
...
9
Molecular Diagnostics: For the Clinical Laboratorian
HETERODUPLEX ANALYSIS IN MUTATION DETECTION Heteroduplex
formation is required for many mutation scanning methods. Heteroduplex
analysis (HA) refers to the technique based on the electrophoretic resolution of
wild-type ...
William B. Coleman, Gregory J. Tsongalis, 2007
The formation of heteroduplex DNA generates a D-loop, which is extended by
repair synthesis, to cover the entire length of the gap. The extended single strand
anneals with complementary sequence at the end, so that heteroduplex DNA ...
8 NEWS ITEMS WHICH INCLUDE THE TERM «HETERODUPLEX»
Find out what the national and international press are talking about and how the term
heteroduplex is used in the context of the following news items.
Diverse Pathways to Drug Targets
... indicated that miravirsen sequesters the liver-specific microRNA miR-122 in a highly stable heteroduplex, thereby inhibiting its function. «Genetic Engineering & Biotechnology News, Apr 15»
Improved transposon-based library preparation for the Ion Torrent …
When such a heteroduplex serves as a template during amplification onto a bead, the bead becomes populated by two different clones and will later be ... «BioTechniques.com, Apr 15»
Makrigiorgos Lab at Dana-Farber Publishes Proof of Concept for …
... of the fact that in some cases preferential amplification of mutant DNA is so great that it obviates the need to form a mutant-wildtype heteroduplex DNA. «GenomeWeb, Apr 14»
Inactivation of an integrated antibiotic resistance gene in …
The mix was incubated at 95°C for 15 min, 65°C for 30 min, room temperature for 30 min, and on ice for 30 min to form heteroduplex DNA. Following the ... «BioTechniques.com, Apr 14»
A method for high-throughput PCR-based genotyping of larval …
It is worth noting that the presence of bands running higher than 412 bp in lanes 2, 3, 4, 6, and 8 indicate DNA heteroduplex formation between mutant and wild ... «BioTechniques.com, Dec 13»
Does the Myriad Decision Presage a Golden Age of Patent-Free …
... SEQ ID NO:1, wherein a germline alteration is detected by forming a heteroduplex consisting of a first strand of nucleic acid selected from the ... «Patent Docs, Jun 13»
Generation of DNA nanocircles containing mismatched bases
... at 37°C. For MutS-DNA complexes, 9 ng 505-bp homoduplex circle, 9 ng 1100-bp heteroduplex circle, and 4 nM MutS were incubated at room temperature for ... «BioTechniques.com, Oct 11»
Formation and branch migration of Holliday junctions mediated by …
... Kmiec, E. B. & Holloman, W. K. Heteroduplex formation and polarity ... P. & West, S. C. Heteroduplex formation by human Rad51 protein: ... «Nature.com, Feb 08»