10 ENGLISH BOOKS RELATING TO «HYDROXYLATION»
Discover the use of
hydroxylation in the following bibliographical selection. Books relating to
hydroxylation and brief extracts from same to provide context of its use in English literature.
1
Principles and Methods of Toxicology, Fifth Edition
Hydroxylation of aliphatic carbon atoms represents one of the most common
reactions in phase I metabolism of xenobiotics. The reaction ... This radical
interacts with activated oxygen (through oxygen rebound) to yield hydroxylation.
2
Foye's Principles of Medicinal Chemistry
Alprenolol (4-hydroxylation) Amitriptyline (10-hydroxylation) Dexfenfluramine
Amphetamine hydroxylation, cleavage ether bond) Aripiprazole Atomoxetine
Bifuralol (1'-hydroxylation) Bisoprolol Captopril Carvedilol Cevimeline Dolasetron
...
Thomas L. Lemke, David A. Williams, 2012
3
Molecular and Applied Aspects of Oxidative Drug Metabolizing ...
Substrate Pathway Substrate Pathway Alprenolol Aromatic hydroxylation
Maprotiline Amiflamine N-Demethylation ... Benzylic hydroxylation
Methoxyamphetamine Aromatic hydroxylation and N-demethylation Aprindine
Aromatic hydroxylation ...
Emel Arinç, John B. Schenkman, Ernest Hodgson, 1999
4
High Throughput Screening: The Discovery of Bioactive Substances
Reaction Substrate Product Microorganism la-hydroxylation ip-hydroxylation 2ot-
hydroxylation 2p-hydroxylation 3oc-hydroxylation 3p-hydroxylation 4p-
hydroxylation 5a-hydroxylation 5p-hydroxylation 6a-hydroxylation 6p-
hydroxylation ...
5
Cytochromes P450: Role in the Metabolism and Toxicity of ...
Aromatic hydroxylation Benzylic hydroxylation Arylamine N-oxidation Aromatic
hydroxylation Aliphatic hydroxylation O-demethylation N-demethylation Benzylic
hydroxylation Aromatic hydroxylation Aromatic hydroxylation Aromatic ...
6
Direct
Hydroxylation of Benzene to Phenol in a ...
proposed, such as the use of a Pd-membrane reactor to perform benzene
hydroxylation. In this case, the Pd-membrane acts as a catalyst for the reaction
and also as a diaphragm to prevent detonation due to the direct contact of
hydrogen with ...
7
The Porphyrin Handbook: Biochemistry and binding: activation ...
Valine-295 was mutated to isoleucine, which resulted in increased selectivity of
hydroxylation for both 1 -methylnorcamphor and norcamphor and no change for
camphor versus the native enzyme. Thus, the increased steric bulk of isoleucine
...
Karl M. Kadish, Kevin M. Smith, Roger Guilard, 2000
8
Principles of Clinical Pharmacology
SCHEME 11.8 Ibuprofen is an example of a drug that undergoes aliphatic
hydroxylation. Other drugs similarly metabolized include terfenadine,
pentobarbital, and cyclosporine. N N para-hydroxyphenytoin SCHEME 11.11 The
metabolism of ...
Arthur J. Atkinson, Jr., Darrell R. Abernethy, Charles E. Daniels, 2011
9
Mechanistic Studies of
Hydroxylation Reactions Catalyzed by ...
These catalysts are not only capable of alkane hydroxylation but also capable of
regio- and stereospecific catalysis of wide range of hydroxylation reactions of
hydrocarbons and chlorinated hydrocarbons.4'6 The hydroxylation mechanisms
of ...
Dharmika Shanthi P. Lansakara-P., 2008
10
ADVANCES IN CANCER RESEARCH
(1957. 1959) 3-Methylcholanthrene (MC) Rat Liver Hydroxylation 3.4-
Benzpyrene Mixed hydroxylat-ion 10 Conney et al. (1957) 1,2,5,6-
Dibenzanthracene Rat Liver Hydroxylation 3,4-Benzpyrene Mixed hydroxylation
10 Conney et al. (1957) ...
10 NEWS ITEMS WHICH INCLUDE THE TERM «HYDROXYLATION»
Find out what the national and international press are talking about and how the term
hydroxylation is used in the context of the following news items.
Column: Healthy Routes
... initial critical step in collagen formation called hydroxylation of proline and lysine amino acids. Vitamin C is required for this first step to occur, ... «MorinvilleNews.com, Jul 15»
Tetrahydrocannabinol in milk and other food of animal origin
Extrahepatic biotransformations resulting in hydroxylation of the pentyl side chain have been documented in brain microsomes from mice, rats, ... «Teatro Naturale, Jun 15»
Secretion of Fc-amidated peptide fusion proteins by Chinese …
C-terminal α-amidation requires the α-hydroxylation of a peptidylglycine precursor by peptidylglycine α-hydroxylating monooxygenase (PHM) ... «BMC Blogs Network, Jun 15»
How abiraterone works
Inhibition of 17α-hydroxylase suppresses hydroxylation of pregnenolone and progesterone at C17. Block of 17,20-lyase limits the subsequent ... «Nature.com, Jun 15»
Building a biofactory
The bottleneck in this process is the hydroxylation of L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA), a transformation that is conducted ... «Nature.com, Jun 15»
Arabidopsis leucine-rich repeat extensin (LRX) proteins modify cell …
Root hair formation appears to be particularly sensitive to changes in this protein network since interfering with proline hydroxylation of ... «BMC Blogs Network, Jun 15»
A lactate-induced response to hypoxia
Oxygen-dependent hydroxylation of HIF-1α and HIF-2α by prolyl hydroxylase domain (PHD) enzymes and ubiquitination by pVHL results in ... «ScienceBlog.com, Jun 15»
Substantial reprogramming of the Eutrema salsugineum …
... N-hydroxylation of 3-indolylmethylglucosinolate in the biosynthesis of Eutrema phytoalexins. EsCYP81F3 (Thhalv10027443m) was induced ... «BMC Blogs Network, Jun 15»
DEGS2 polymorphism associated with cognition in schizophrenia is …
As the ceramide structure varies due to varying hydroxylation and desaturation in the sphingoid base, the DEGS2 gene has a role in ... «Nature.com, Apr 15»
Learning the proper use of vitamin D
It then moves to the kidney for 1-hydroxylation which then produces the active product known as 1-25-dihydroxy vitamin D. Some individuals ... «Montgomery Advertiser, Mar 15»
