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Meaning of "isoniazid" in the English dictionary

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DICTIONARY
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ETYMOLOGY OF THE WORD ISONIAZID

Isoni( cotinic acid hydr) azid( e).
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Etymology is the study of the origin of words and their changes in structure and significance.
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PRONUNCIATION OF ISONIAZID

isoniazid  [ˌaɪsəʊˈnaɪəzɪd] play
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GRAMMATICAL CATEGORY OF ISONIAZID

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Isoniazid is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES ISONIAZID MEAN IN ENGLISH?

Isoniazid

Isoniazid, also known as isonicotinylhydrazine, is an organic compound that is the first-line medication in prevention and treatment of tuberculosis. The compound was first synthesized in the early 20th century, but its activity against tuberculosis was first reported in the early 1950s, and three pharmaceutical companies attempted unsuccessfully to simultaneously patent the drug, the most prominent one being Roche, which launched its version, Rimifon, in 1952. The drug was first tested at Many Farms, a Navajo community, due to the Navajo reservation's dire tuberculosis problem and the fact that the population was naïve with respect to streptomycin, the main tuberculosis treatment at the time. With the introduction of isoniazid, a cure for tuberculosis was first considered reasonable. Isoniazid is available in tablet, syrup, and injectable forms. It is available worldwide, is inexpensive and is generally well tolerated. It is manufactured from isonicotinic acid, which is produced from 4-methylpyridine. The abbreviation INH is common for referring to isoniazid, but abbreviating drug names is not best practice in medicine.

Definition of isoniazid in the English dictionary

The definition of isoniazid in the dictionary is a soluble colourless crystalline compound used to treat tuberculosis. Formula: C6H7N3O.

WORDS THAT RHYME WITH ISONIAZID


busied
ˈbɪzɪd
daisied
ˈdeɪzɪd
easied
ˈiːzɪd
frenzied
ˈfrɛnzɪd
iproniazid
ˌaɪprəˈnaɪəˌzɪd
isocarboxazid
ˌaɪsəʊkɑːˈbɒksəzɪd
palsied
ˈpɔːlzɪd
pansied
ˈpænzɪd
resid
ˈrezɪd

WORDS THAT BEGIN LIKE ISONIAZID

isometrical
isometrically
isometrics
isometropia
isometry
isomorph
isomorphic
isomorphically
isomorphism
isomorphous
isoniazide
isonitrile
isonome
isonomic
isonomous
isonomy
isooctane
isopach
isopachyte
isoperimeter

WORDS THAT END LIKE ISONIAZID

acid
aid
android
avoid
bid
David
did
grid
id
kid
liquid
Madrid
mid
paid
rapid
said
solid
stupid
valid
vid

Synonyms and antonyms of isoniazid in the English dictionary of synonyms

SYNONYMS

Translation of «isoniazid» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF ISONIAZID

Find out the translation of isoniazid to 25 languages with our English multilingual translator.
The translations of isoniazid from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «isoniazid» in English.

Translator English - Chinese

异烟肼
1,325 millions of speakers

Translator English - Spanish

isoniazida
570 millions of speakers

English

isoniazid
510 millions of speakers

Translator English - Hindi

आइसोनियाज़िड
380 millions of speakers
ar

Translator English - Arabic

الإيزونيازيد
280 millions of speakers

Translator English - Russian

изониазид
278 millions of speakers

Translator English - Portuguese

isoniazida
270 millions of speakers

Translator English - Bengali

isoniazid
260 millions of speakers

Translator English - French

isoniazide
220 millions of speakers

Translator English - Malay

Isoniazid
190 millions of speakers

Translator English - German

Isoniazid
180 millions of speakers

Translator English - Japanese

イソニアジド
130 millions of speakers

Translator English - Korean

이소니아지드
85 millions of speakers

Translator English - Javanese

Isoniazid
85 millions of speakers
vi

Translator English - Vietnamese

isoniazid
80 millions of speakers

Translator English - Tamil

isoniazid
75 millions of speakers

Translator English - Marathi

आयोनियानाजिड
75 millions of speakers

Translator English - Turkish

izoniazid
70 millions of speakers

Translator English - Italian

isoniazide
65 millions of speakers

Translator English - Polish

izoniazyd
50 millions of speakers

Translator English - Ukrainian

ізоніазид
40 millions of speakers

Translator English - Romanian

izoniazida
30 millions of speakers
el

Translator English - Greek

ισονιαζίδη
15 millions of speakers
af

Translator English - Afrikaans

isoniasied
14 millions of speakers
sv

Translator English - Swedish

isoniazid
10 millions of speakers
no

Translator English - Norwegian

isoniazid
5 millions of speakers

Trends of use of isoniazid

TRENDS

TENDENCIES OF USE OF THE TERM «ISONIAZID»

The term «isoniazid» is regularly used and occupies the 75.000 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Regularly used
65
/100
The map shown above gives the frequency of use of the term «isoniazid» in the different countries.
Principal search tendencies and common uses of isoniazid
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «isoniazid».

FREQUENCY OF USE OF THE TERM «ISONIAZID» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «isoniazid» during the past 500 years. Its implementation is based on analysing how often the term «isoniazid» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about isoniazid

EXAMPLES

10 ENGLISH BOOKS RELATING TO «ISONIAZID»

Discover the use of isoniazid in the following bibliographical selection. Books relating to isoniazid and brief extracts from same to provide context of its use in English literature.
1
Handbook of Drug-Nutrient Interactions
Pyridoxine and Isoniazid Isoniazid isan antimycobacterial agent used forthe treatment and prophylaxisof Mycobacterium tuberculosis infections. Peripheral neuropathy is the most common side effect of isoniazid therapy (135). Peripheral  ...
Joseph I. Boullata, Vincent T. Armenti, 2010
2
Herb, Nutrient, and Drug Interactions: Clinical Implications ...
Research The action of isoniazid and related antitubercular drugs as pyridoxine antagonists is generally agreed on, and the efficacy of pyridoxine in countering the toxic effects of isoniazid is well established.107,113 Nevertheless, the issue of ...
Mitchell Bebel Stargrove, Jonathan Treasure, Dwight L. McKee, 2008
3
Antibiotics in Laboratory Medicine
With this in mind, it is possible that the oxidized derivatives of isoniazid that bind to and inhibit InhA and KasA are different. Whether the primary target of isoniazid is InhA or KasA, or both, the mycolic acid anabolic pathways are a focus of ...
Victor Lorian, 2005
4
Drugs in Pregnancy and Lactation: A Reference Guide to Fetal ...
Antituberculosis Agent PREGNANCY RECOMMENDATION: Compatible - Maternal Benefit >> Embryo-Fetal Risk BREASTFEEDING RECOMMENDATION: Limited Human Data - Probably Compatible PREGNANCY SUMMARY Isoniazid does ...
Gerald G. Briggs, Roger K. Freeman, Sumner J. Yaffe, 2011
5
Drug Metabolism and Transport: Molecular Methods and Mechanisms
demonstrated that acetylisoniazid was the primary metabolite of isoniazid excreted in urine and that patients were distributed into groups that excreted either a high or low amount of acetylisoniazid. Moreover, they found that patients who ...
Lawrence H. Lash, 2005
6
Modern Pharmacology with Clinical Applications
These agents include isoniazid. rifampin, pyrazinamide. ethambutol, and streptomycin. Most patients with tuberculosis can be treated successfully with these drugs. Second-line drugs are more toxic and less effective, and they are indicated ...
Charles R. Craig, Robert E. Stitzel, 2004
7
Study of Isoniazid-resistant Tuberculosis: Mycobacterial ...
Lancet 2006; 368:2142-2154. 27. Benator D, Bhattacharya M, Bozeman L, Burman W, Cantazaro A, Chaisson R, Gordin F, Horsburgh CR, Horton J, Khan A, et al. Rifapentine and isoniazid once a week versus rifampicin and isoniazid twice a ...
Patricio Escalante, 2007
8
Liver Disease in Children
Isoniazid has been associated with a wide spectrum of hepatotoxicity in adults. It is an important cause of drug hepatotoxicity wherever tuberculosis is highly prevalent. The most frequent abnormality is asymptomatic elevation of serum ...
Frederick J. Suchy, Ronald J. Sokol, William F. Balistreri, 2014
9
Mycobacteria: Basic Aspects
Probing isoniazid-resistant mutants of M. tuberculosis showed that in two out of the three catalase-negative strains resistant to >50 //g/ml of INH, the katG gene was deleted, leading to the hypothesis that isoniazid resistance in tubercle bacilli  ...
Pattisapu R.J. Gangadharam, P.A. Jenkins, 1998
10
Antimicrobial Drug Resistance: Mechanisms of Drug ...
inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis. Science 263, 227–230 37. Quemard, A., Sacchettini, J. C., Dessen, A., Vilcheze, C., Bittman, R., Jacobs, W. R., Jr. & Blanchard, J. S. (1995).
Douglas Mayers, 2009

10 NEWS ITEMS WHICH INCLUDE THE TERM «ISONIAZID»

Find out what the national and international press are talking about and how the term isoniazid is used in the context of the following news items.
1
Combating the Global Epidemics of Diabetes, Tuberculosis
“We have considered patients with latent TB infection to be some of the highest priority candidates for isoniazid chemoprophylaxis to prevent ... «Endocrinology Advisor, Jul 15»
2
Share this article
Since we could not exclude the possibility of TB or TB-IRIS, we added isoniazid (300 mg per day) to the chemotherapy regimen. We also ... «BMC Blogs Network, Jul 15»
3
Study shows Otsuka's TB drug works even in worst cases - PMLiVE
The WHO defines XDR-TB as resistance to first-line drugs isoniazid and rifampicin, as well as resistance to at least one fluoroquinolone and ... «PMLiVE, Jul 15»
4
Two Drugs Promising in XDR-TB
Most cases of TB succumb to a regimen of isoniazid (Nydrazid), rifampin (Rifadin), ethambutol (Myambutol) and pyrazinamide for 8 weeks, ... «MedPage Today, Jul 15»
5
Mood-altering Drugs That Were Invented by Accident - Io9
Isoniazid had been a fantastically successful tuberculosis drug at a time when the world really needed tuberculosis drugs. Getting tuberculosis ... «io9, Jul 15»
6
Global isoniazid-resistant TB cases in children varies widely
More than 120,000 children worldwide are estimated to become infected with isoniazid-resistant forms of tuberculosis annually, with the ... «Healio, Jul 15»
7
Retrospective Study Confirms Need for LTBI Screening Prior to …
All the patients were treated with isoniazid (INH) for nine months, and biologic therapy was restarted after one month of treatment with INH ... «MD Magazine, Jul 15»
8
Grozny: New TB drug regimen helps patients with extensive …
MDR-TB is resistant to at least two of the best anti-TB drugs, isoniazid and rifampicin. These drugs are considered first-line drugs and are used ... «Médecins Sans Frontières International, Jul 15»
9
Starke lends expertise to national advisory committee to end …
Fortunately, a new treatment for infection combines Isoniazid with another drug that one only has to take once a week for 12 weeks, just 12 ... «Baylor College of Medicine News, Jul 15»
10
Nudge to tweak TB treatment rules
... tools that test for MDR-TB. "We ideally need a test that detects resistance for both rifampicin and isoniazid (another anti-TB drug)," said Singh. «Calcutta Telegraph, Jul 15»

REFERENCE
« EDUCALINGO. Isoniazid [online]. Available <https://educalingo.com/en/dic-en/isoniazid>. Apr 2024 ».
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