10 ENGLISH BOOKS RELATING TO «MERCAPTOPURINE»
Discover the use of
mercaptopurine in the following bibliographical selection. Books relating to
mercaptopurine and brief extracts from same to provide context of its use in English literature.
1
Side Effects of Drugs Annual: A worldwide yearly survey of ...
Hematologic Thioguanine improved 7-year event-free survival and freedom from
isolated central nervous system relapse more than mercaptopurine in 2030
children with standard-risk acute lymphoblastic leukemia [163c]. However, 51 ...
USES: Mercaptopurine is used in the treatment of childhood acute leukaemias.
MECHANISM OF ACTION: Mercaptopurine (a purine antagonist) is a cell cycle-
specilic cytotoxic agent which is only effective against cells that are actively
dividing ...
3
Cancer Chemotherapy and Biotherapy: Principles and Practice
Phase I and clinical pharmacological study of mercaptopurine administered as a
prolonged intravenous infusion. Cancer Res 1985;45:1869–1873. 19. Lafolie P,
Hayder S, Bjork O, et al. Intraindividual variation in 6-mercap- topurine ...
Bruce A. Chabner, Dan L. Longo, 2011
4
Immunosuppression in Inflammatory Bowel Diseases: Standards, ...
9. Azathioprine/6-mercaptopurine: mechanisms. of. action,. pharmacology. and.
toxicology. W. J. SANDBORN INTRODUCTION 6-Mercaptopurine and its prodrug
azathioprine are effective in inducing and maintaining remission in patients with ...
K. Fellermann, D.P. Jewell, W.J. Sandborn, 2001
5
Consumers Guide to Cancer Drugs
How. Drug. Works: Mercaptopurine prevents cells from making DNA and RNA by
interfering with the synthesis of nucleic acids, thus stopping the growth of cancer
cells, and causing them to die.
Gail M. Wilkes, Terri B. Ades, 2004
6
Inflammatory Bowel Diseases 1990
The toxic side effects of current agents are substantial; e.g. with 6-
mercaptopurine or Azathioprine one in ten 235 D. Rachmilewitz and].
Zimmerman (eds.), Inflammatory Bowel Diseases 1990, 235-241. © l 990 Kluwer
Academic Publishers.
D. Rachmilewitz, Joseph Zimmerman, 1990
7
Adverse Drug Interactions: A Handbook for Prescribers
Lakshman Delgoda Karalliedde, Simon F.J. Clarke, Ursula Collignon, Janaka
Karalliedde. MERCAPTOPURINE MERCAPTOPURINE ANTIBIOTICS – CO-
TRIMOXAZOLE ≠ risk of bone marrow toxicity Additive effect Avoid co-
administration ...
Lakshman Delgoda Karalliedde, Simon F.J. Clarke, Ursula Collignon, 2010
8
Essential Drug Data for Rational Therapy in Veterinary Practice
inhibition of the cellular immune response also occurs. There is usually complete
cross-resistance between mercaptopurine and thioguanine. Mechanism of Action
—Mercaptopurine is converted to the active nucleotide form (6-thioinosine-5' ...
Kingsley Eghianruwa, 2014
9
Textbook of Pediatric Gastroenterology and Nutrition
of either direct suppression of linear growth or an inability to control disease
activity fully.151 Immunoregulatory agents Azathioprine and 6-mercaptopurine
Growing evidence supports the use of the immunoregulatory agents azathioprine
and ...
10
Renal Pharmacotherapy: Dosage Adjustment of Medications ...
Mercaptopurine Selected References Aronoff GA, Bennett WM, Berns JS, et al.
Drug prescribing in renal failure: dosing guidelines for adults and children. 5th ed
. Philadelphia: American College of Physicians; 2007. Balis FM, Adamson PC.
Larry K Golightly, Isaac Teitelbaum, Tyree H. Kiser, 2013
10 NEWS ITEMS WHICH INCLUDE THE TERM «MERCAPTOPURINE»
Find out what the national and international press are talking about and how the term
mercaptopurine is used in the context of the following news items.
Experts Serve Up Guidelines for IgG4-related Disease
Azathioprine, mycophenolate mofetil, 6-mercaptopurine, methotrexate tacrolimus, and cyclophosphamide have all been used by various ... «MedPage Today, Jul 15»
Genetic screening reveals a link between Wnt signaling and …
Methotrexate (MTX), 6-mercaptopurine, paclitaxel (PX; Taxol) and colchicine (COL) were obtained from Tocris Bioscience (Bristol, UK). «Nature.com, Jul 15»
As PGx Program Grows, Vanderbilt Hoping to Expand Reported …
... at Vanderbilt have TPMT alleles that placed them at risk for responding poorly to thiopurines — drugs such as azathioprine, mercaptopurine, ... «GenomeWeb, Jun 15»
Crohns Disease Market – Global Industry Analysis and Forecast …
Azathioprine, mercaptopurine, infliximab, adalimumab, and certolizumab pegol are some of the immune system suppressors used for the ... «Medgadget.com, Jun 15»
Death after hospital policy slip-ups
... 41, was admitted with irritable bowel syndrome and suspected Crohn's disease on February 4 and prescribed the drug mercaptopurine. «The West Australian, Jun 15»
SIMPONI® Receives European Commission Approval for Treatment …
... including corticosteroids and 6-mercaptopurine or azathioprine, or who are intolerant to or have medical contraindications for such therapies. «PR Newswire, Jun 15»
EU approves Simponi to treat non-radiographic axial spondyloarthritis
... including corticosteroids and 6-mercaptopurine or azathioprine, or who are intolerant to or have medical contraindications for such therapies. «pharmabiz.com, Jun 15»
Fiona Stanley inquiry: Hospital staff errors contributed to Perth man's …
Phillip Olsen told the inquiry his son had been given mercaptopurine, but a blood test showed he was missing the TPMT enzyme required to ... «ABC Online, Jun 15»
Scans Detect Complete Normalization in Crohn's Patients
The six patients were also taking combination therapy with a thiopurine (azathioprine or 6-mercaptopurine). The researchers observed no significant differences ... «Gastroenterology & Endoscopy News, Jun 15»
6-Mercaptopurine reduces cytokine and Muc5ac expression …
6-Mercaptopurine reduces cytokine and Muc5ac expression involving inhibition of NF¿B activation in airway epithelial cells ... «7thSpace Interactive, Jun 15»
