Download the app
educalingo
Search

Meaning of "microsomal" in the English dictionary

Dictionary
DICTIONARY
section

PRONUNCIATION OF MICROSOMAL

microsomal  [ˌmaɪkrəˈsəʊməl] play
facebooktwitterpinterestwhatsapp

GRAMMATICAL CATEGORY OF MICROSOMAL

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Microsomal is an adjective.
The adjective is the word that accompanies the noun to determine or qualify it.

WHAT DOES MICROSOMAL MEAN IN ENGLISH?

microsomal

Microsome

In cell biology, microsomes are vesicle-like artifacts re-formed from pieces of the endoplasmic reticulum when eukaryotic cells are broken-up in the laboratory; by definition, microsomes are not ordinarily present in living cells. Microsomes can be concentrated and separated from other cellular debris by differential centrifugation. Unbroken cells, nuclei, and mitochondria sediment out at 10,000g, whereas soluble enzymes and fragmented ER, which contains cytochrome P450, remain in solution. At 100,000g, achieved by faster centrifuge rotation, ER sediments out of solution as a pellet but the soluble enzymes remain in the supernatant. In this way, cytochrome P450 in microsomes is concentrated and isolated. Microsomes have a reddish brown color, due to the presence of the iron-containing co-factor, heme, in the P450s. P450s are highly abundant in livers of rats, mice and humans. Microsomes are a valuable tool for investigating the metabolism of compounds and for examining drug-drug interactions by in vitro-research. Researchers often select microsome lots based on the enzyme activity level of specific CYPs.

Definition of microsomal in the English dictionary

The definition of microsomal in the dictionary is of or relating to any of the small particles consisting of ribosomes and fragments of attached endoplasmic reticulum that can be isolated from cells by centrifugal action.

WORDS THAT RHYME WITH MICROSOMAL


acrosomal
ˈækrəˌsəʊməl
autosomal
ˈɔːtəʊˌsəʊməl
chondriosomal
ˌkɒndrɪəˈsəʊməl
chromosomal
ˌkrəʊməˈsəʊməl
desmosomal
ˌdezməˈsəʊməl
episomal
ˌepɪˈsəʊməl
hydrosomal
ˌhaɪdrəˈsəʊməl
liposomal
ˌlɪpəˈsəʊməl
lysosomal
ˌlaɪsəʊˈsəʊməl
nonchromosomal
ˌnɒnˌkrəʊməˈsəʊməl
nucleosomal
ˌnjuːklɪəˈsəʊməl
peroxisomal
pəˌrɒksɪˈsəʊməl
polyribosomal
ˌpɒlɪˌraɪbəˈsəʊməl
prosomal
prəʊˈsəʊməl
ribosomal
ˌraɪbəˈsəʊməl
sarcosomal
ˌsɑːkəʊˈsəʊməl
schistosomal
ˌʃɪstəˈsəʊməl
stromal
ˈstrəʊməl
synaptosomal
ˌsɪnæptəˈsəʊməl
trypanosomal
ˌtrɪpənəˈsəʊməl

WORDS THAT BEGIN LIKE MICROSOMAL

microscopy
microsecond
microseism
microseismic
microseismical
microseismicity
microsite
microskirt
microsleep
microsmatic
microsome
microspecies
microsphere
microspherical
microsporangia
microsporangium
microspore
microsporic
microsporocyte
microsporophyll

WORDS THAT END LIKE MICROSOMAL

abnormal
animal
bromal
comal
decimal
dermatomal
enterostomal
formal
informal
maximal
minimal
normal
optimal
paranormal
peristomal
primal
prodromal
rhabdomal
stomal
thermal

Synonyms and antonyms of microsomal in the English dictionary of synonyms

SYNONYMS

Translation of «microsomal» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF MICROSOMAL

Find out the translation of microsomal to 25 languages with our English multilingual translator.
The translations of microsomal from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «microsomal» in English.

Translator English - Chinese

微粒
1,325 millions of speakers

Translator English - Spanish

microsomal
570 millions of speakers

English

microsomal
510 millions of speakers

Translator English - Hindi

माइक्रोसोमल
380 millions of speakers
ar

Translator English - Arabic

الميكروسومي
280 millions of speakers

Translator English - Russian

микросомальный
278 millions of speakers

Translator English - Portuguese

microssomal
270 millions of speakers

Translator English - Bengali

মাইক্রোসোমাল
260 millions of speakers

Translator English - French

microsomes
220 millions of speakers

Translator English - Malay

Microsomal
190 millions of speakers

Translator English - German

mikrosomalen
180 millions of speakers

Translator English - Japanese

ミクロソーム
130 millions of speakers

Translator English - Korean

미세 소체
85 millions of speakers

Translator English - Javanese

Microsomal
85 millions of speakers
vi

Translator English - Vietnamese

microsome
80 millions of speakers

Translator English - Tamil

மைக்ரோசோமல்
75 millions of speakers

Translator English - Marathi

मायक्रोसोमल
75 millions of speakers

Translator English - Turkish

mikrozomal
70 millions of speakers

Translator English - Italian

microsomiale
65 millions of speakers

Translator English - Polish

mikrosomalnych
50 millions of speakers

Translator English - Ukrainian

мікросомальний
40 millions of speakers

Translator English - Romanian

microzomale
30 millions of speakers
el

Translator English - Greek

μικροσωμικά
15 millions of speakers
af

Translator English - Afrikaans

mikrosomale
14 millions of speakers
sv

Translator English - Swedish

mikrosomalt
10 millions of speakers
no

Translator English - Norwegian

mikrosomal
5 millions of speakers

Trends of use of microsomal

TRENDS

TENDENCIES OF USE OF THE TERM «MICROSOMAL»

The term «microsomal» is regularly used and occupies the 84.838 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Regularly used
61
/100
The map shown above gives the frequency of use of the term «microsomal» in the different countries.
Principal search tendencies and common uses of microsomal
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «microsomal».

FREQUENCY OF USE OF THE TERM «MICROSOMAL» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «microsomal» during the past 500 years. Its implementation is based on analysing how often the term «microsomal» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about microsomal

EXAMPLES

10 ENGLISH BOOKS RELATING TO «MICROSOMAL»

Discover the use of microsomal in the following bibliographical selection. Books relating to microsomal and brief extracts from same to provide context of its use in English literature.
1
Endocrine Autoimmunity and Associated Conditions
Thyroid antibodies Amino et al. [2] first documented the association of postpartum thyroiditis with high titres of thyroid antibodies, and the dramatic rise of microsomal (TPO) antibody titre after delivery was clearly shown in the study of Fung et al ...
Anthony P. Weetman, 1998
2
Pesticide Residues in Food - 2004: Evaluations 2004, ...
The liver samples were separated into microsomal and cytosolic fractions and the following biochemical parameters were investigated: protein content of microsomal and cytosolic fractions; microsomal cytochrome P450; microsomal ...
World Health Organization, 2006
3
Clinically Oriented Pharmacology
Microsomal enzymes are located on smooth endoplasmic reticulum in the cells of liver, lungs, kidneys are located on ... NonNonNonNon----microsomal enzym microsomal enzym microsomal enzym microsomal enzymes:es:es:es: They are ...
Dr J G Buch
4
Conjugation-Dependent Carcinogenicity and Toxicity of ...
McLellan, L. 1., Wolf, C. R., and Hayes, J. D. (1989). Human microsomal glutathione Stransferase, Its involvement in the conjugation of hexachloro-1.3- butadiene with glutathione. Biochem. J. 258, 87-93. Morgenstem, R., and DePierre, J. W. ...
‎1994
5
The Enzymes
Schlossman and Bell critically addressed the question of whether the microsomal glycerol-P acyltransferase activity and the dihydroxyacetoneP acyltransferase activity were dual catalytic functions of a single microsomal enzyme (13).
Paul D. Boyer, 1983
6
Hormonal Steroids: Proceedings of the Fifth International ...
Fig. 6. Ouehterlony immunodiffusion plate with antibodies in centre'well. In outer wells are: 1 and 4. microsomal extract: 2 and 5. cytosol; 3 and 6. purified E2 binder [If]. Table 4. Oestradiol receptor concentration in the pancreas in comparison.
V. H. T. James, J. R. Pasqualini, 1979
7
Postharvest Biology and Technology of Fruits, Vegetables, ...
The microsomal PLD also showed dual optimal values of activation at pH values of 5 and 7, respectively. Similar pH activation profiles have been observed in tomato microsomal membrane (K. Tiwari, unpublished). 9.3.2.2 Kinetic analysis of ...
Gopinadhan Paliyath, Ph.D., Dennis P. Murr, Avtar K. Handa, 2009
8
Phytochemical Biopesticides
In most instances, induction of various microsomal monooxygenase activities by allelochemicals was higher than that of cytochrome P450 content (Yu 1982, 1983 , 1985; Yu and Ing 1984; Moldenke et al. 1983; Snyder et al. 1993) and there ...
Opender Koul, G. S. Dhaliwal, 2003
9
Toxicology of Glutathione Transferases
Liver Dis., 35 Suppl. 2, S49-S60, 2003. 101. Lundqvist, G. and Morgenstern, R., Mechanism of activation of rat liver microsomal glutathione transferase by noradrenaline and xanthine oxidase, Biochem. Pharmacol, 43 (8), 1725-1728, 1992.
Yogesh C. Awasthi, 2006
10
Autoantibodies
... Liver Cytosol Antigen Type 1 Autoantibodies (LC-1), Liver Kidney Microsomal Autoantibodies (LKM), and Liver Microsomal Autoantibodies (LM) 477 Liver Kidney Microsomal/Liver Microsomal Autoantibodies, ...
Yehuda Shoenfeld, Pier Luigi Meroni, M. Eric Gershwin, 2013

10 NEWS ITEMS WHICH INCLUDE THE TERM «MICROSOMAL»

Find out what the national and international press are talking about and how the term microsomal is used in the context of the following news items.
1
KLF5 promotes breast cancer proliferation, migration and invasion in …
Kruppel-like factor 5 transcription factor promotes microsomal prostaglandin E2 synthase 1 gene transcription in breast cancer. J Biol Chem ... «Nature.com, Jul 15»
2
Welcome to to the Irish Medical Times website
Drug interactions: Microsomal enzyme-inducing drugs, use a barrier method during and for 28 days after admin. Medicinal charcoal. Adverse ... «Irish Medical Times, Jul 15»
3
The maize cytochrome P450 CYP79A61 produces …
The resulting microsomal protein fraction was homogenized in 2 mL TEG buffer (50 mM Tris–HCl, 1 mM EDTA, 30 % w/v glycerol) using a glass ... «BMC Blogs Network, May 15»
4
Aegerion Pharmaceuticals Achieves Primary Endpoint in Phase III …
Lomitapide, marketed as JUXTAPID® in the U.S., is a microsomal triglyceride transfer protein (MTP) inhibitor that works independently of LDL ... «GlobeNewswire, May 15»
5
Temporal gene expression profiling of the rat knee joint capsule …
P4HB is a microsomal triglyceride transfer protein involved in intracellular lipid exchange [16] and levels of the corresponding transcript and ... «BMC Blogs Network, May 15»
6
Aminomethyl spectinomycins as therapeutics for drug-resistant …
Compounds also demonstrated no mammalian cytotoxicity, improved microsomal stability, and favorable pharmacokinetic properties in rats. The lead compound ... «Science Magazine, May 15»
7
A Comprehensive Update On DURECT Corp. (DRRX)
It also inhibits lipid absorption and transportation by blocking microsomal triglyceride transfer protein (MTP) similar to Aegerion's Juxtapid ... «Seeking Alpha, May 15»
8
AOP Orphan Launches Lojuxta® (lomitapide) for Treatment of …
Lojuxta's mechanism of action is independent of the LDL receptors and is based on inhibiting the microsomal triglyceride transfer protein that is ... «b3c newswire, Apr 15»
9
AOP Orphan Launches Lojuxta to the Austrian Market
Lojuxta's mechanism of action is independent of the LDL receptors and is based on inhibiting the microsomal triglyceride transfer protein that is ... «Drug Discovery & Development, Apr 15»
10
Aegerion Pharmaceuticals Expects Little Growth In 2015 (AEGR)
Aegerion's core product is Juxtapid (sold as Lojuxta in Europe), a microsomal triglyceride transfer protein (MTP) inhibitor indicated as an ... «Seeking Alpha, Mar 15»

REFERENCE
« EDUCALINGO. Microsomal [online]. Available <https://educalingo.com/en/dic-en/microsomal>. May 2024 ».
Download the educalingo app
en
English dictionary
Discover all that is hidden in the words on
index
a b c d e f g h i j k l m n o p q r s t u v w x y z