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Meaning of "telomerase" in the English dictionary

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DICTIONARY
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PRONUNCIATION OF TELOMERASE

telomerase  [tɛˈlɒməˌreɪz] play
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GRAMMATICAL CATEGORY OF TELOMERASE

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Telomerase is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES TELOMERASE MEAN IN ENGLISH?

telomerase

Telomerase

Telomerase also called telomere terminal transferase is a ribonucleoprotein that is an enzyme that adds DNA sequence repeats to the 3' end of DNA strands in the telomere regions, which are found at the ends of eukaryotic chromosomes. This region of repeated nucleotide called telomeres contains noncoding DNA and hinders the loss of important DNA from chromosome ends. As a result, every time the chromosome is copied, only 100–200 nucleotides are lost, which causes no damage to the organism's DNA. Telomerase is a reverse transcriptase that carries its own RNA molecule, which is used as a template when it elongates telomeres, which are shortened after each replication cycle. The existence of a compensatory mechanism for telomere shortening was first predicted by Soviet biologist Alexey Olovnikov in 1973, who also suggested the telomere hypothesis of aging and the telomere's connections to cancer. Telomerase was discovered by Carol W. Greider and Elizabeth Blackburn in 1984 in the ciliate Tetrahymena. Together with Jack W. Szostak, Greider and Blackburn were awarded the 2009 Nobel Prize in Physiology or Medicine for their discovery.

Definition of telomerase in the English dictionary

The definition of telomerase in the dictionary is an enzyme that is involved in the formation and repair of telomeres, so that chromosomes are not shortened during cell division.

WORDS THAT RHYME WITH TELOMERASE


anticholinesterase
ˌæntɪˌkɒləˈnɛstəˌreɪz
appraise
əˈpreɪz
apyrase
ˈæpəˌreɪz
craze
kreɪz
epimerase
ˈepɪməˌreɪz
erase
ɪˈreɪz
fraise
freɪz
fundraise
ˈfʌndˌreɪz
graze
ɡreɪz
gyrase
ˈdʒaɪˌreɪz
mores
ˈmɔːreɪz
paraphrase
ˈpærəˌfreɪz
phrase
freɪz
polymerase
pəˈlɪməreɪz
praise
preɪz
raise
reɪz
rase
reɪz
raze
reɪz
rephrase
riːˈfreɪz
strays
streɪz

WORDS THAT BEGIN LIKE TELOMERASE

tellurium
tellurize
tellurometer
tellurous
Tellus
telly
telnet
telocentric
Teloekbetoeng
telome
telomere
telomerisation
telomerization
telomic
telophase
telophasic
telos
telotaxis
telpher
telpher line

WORDS THAT END LIKE TELOMERASE

acetylcholinesterase
anhydrase
carbonic anhydrase
catch phrase
cholinesterase
chrysoprase
diaphorase
esterase
idocrase
isomerase
luciferase
noun phrase
pectinesterase
prepositional phrase
sucrase
to coin a phrase
topoisomerase
transferase
turn of phrase
verb phrase

Synonyms and antonyms of telomerase in the English dictionary of synonyms

SYNONYMS

Translation of «telomerase» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF TELOMERASE

Find out the translation of telomerase to 25 languages with our English multilingual translator.
The translations of telomerase from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «telomerase» in English.

Translator English - Chinese

端粒酶
1,325 millions of speakers

Translator English - Spanish

telomerasa
570 millions of speakers

English

telomerase
510 millions of speakers

Translator English - Hindi

टेलोमिरेज
380 millions of speakers
ar

Translator English - Arabic

التيلوميراز
280 millions of speakers

Translator English - Russian

теломераза
278 millions of speakers

Translator English - Portuguese

telomerase
270 millions of speakers

Translator English - Bengali

telomerase
260 millions of speakers

Translator English - French

télomérase
220 millions of speakers

Translator English - Malay

Telomerase
190 millions of speakers

Translator English - German

Telomerase
180 millions of speakers

Translator English - Japanese

テロメラーゼ
130 millions of speakers

Translator English - Korean

텔로 머라 아제
85 millions of speakers

Translator English - Javanese

Telomerase
85 millions of speakers
vi

Translator English - Vietnamese

telomerase
80 millions of speakers

Translator English - Tamil

telomerase
75 millions of speakers

Translator English - Marathi

टेलोमेरेसझ
75 millions of speakers

Translator English - Turkish

telomeraz
70 millions of speakers

Translator English - Italian

telomerasi
65 millions of speakers

Translator English - Polish

telomerazy
50 millions of speakers

Translator English - Ukrainian

теломераза
40 millions of speakers

Translator English - Romanian

telomerazei
30 millions of speakers
el

Translator English - Greek

τελομεράση
15 millions of speakers
af

Translator English - Afrikaans

telomerase
14 millions of speakers
sv

Translator English - Swedish

telomeras
10 millions of speakers
no

Translator English - Norwegian

telomerase
5 millions of speakers

Trends of use of telomerase

TRENDS

TENDENCIES OF USE OF THE TERM «TELOMERASE»

The term «telomerase» is regularly used and occupies the 92.710 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Regularly used
57
/100
The map shown above gives the frequency of use of the term «telomerase» in the different countries.
Principal search tendencies and common uses of telomerase
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «telomerase».

FREQUENCY OF USE OF THE TERM «TELOMERASE» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «telomerase» during the past 500 years. Its implementation is based on analysing how often the term «telomerase» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about telomerase

EXAMPLES

10 ENGLISH BOOKS RELATING TO «TELOMERASE»

Discover the use of telomerase in the following bibliographical selection. Books relating to telomerase and brief extracts from same to provide context of its use in English literature.
1
Telomeres and Telomerase in Cancer
Telomerase, an enzyme that maintains telomeres and endows eukaryotic cells with immortality, was first discovered in tetrahymena in 1985.
Keiko Hiyama, 2009
2
Bio-Identical Hormones and Telomerase: The Nobel ...
The story has been the same throughout history, so we wonder if we should continue to fight the battle, or if we should just learn to grow old gracefully.
Edmund Chein, Dr Hiroshi Demura MD Phd, 2011
3
Telomeres and Telomerase: Methods and Protocols [Recurso ...
Telomeres and Telomerase: Methods and Protocols provides the core array of productive techniques needed today to develop telomerase inhibitors or diagnostic/prognostic telomerase markers.
John A. Double, Michael J. Thompson, 2002
4
Telomerase Inhibition: Strategies and Protocols
Telomerase Inhibition provides methods and protocols for those researchers. The techniques described in this book should provide the researcher with a diverse and comprehensive set of tools with which to study telomerase inhibition.
Lucy Andrews, Trygve O. Tollefsbol, 2007
5
Telomeres and Telomerase
The evidence for this is twofold: the telomeres of certain cells in culture shorten during their lifespan; and immortalization of cells is associated, at least in some cases, with the maintenance of telomeres and telomerase activity.
CIBA Foundation Symposium, 2008
6
Regulation of Telomerase Gene Expression and Function in ...
Many human carcinoma lines are immortal in vitro, suggesting that these cells have a mechanism for maintaining the ends of their chromosomes.
Dan C. Nguyen, 2006
7
Telomerase Modulation and Its Effect on Antiviral Activity ...
The work described in this dissertation focuses mainly on the use of a small-molecule telomerase activator, TAT2, to enhance anti-viral function of CD8+ T lymphocytes.
Steven Russell Fauce, 2007
8
Telomerase, aging and disease
This volume of Advances in Cell Aging and Gerontology critically reviews the rapidly advancing area of telomerase research with a focus at the molecular and cellular levels.
Mark Paul Mattson, 2001
9
Telomeres and telomerase
The evidence for this is twofold: the telomeres of certain cells in culture shorten during their lifespan; and immortalization of cells is associated, at least in some cases, with the maintenance of telomeres and telomerase activity.
Derek Chadwick, Gail Cardew, 1997
10
Handbook of Stem Cells
levels of telomerase activity. Yet, patients with autosomal dominant DKC typically suffer from progressive aplastic anemia, immune deficiencies, or cancer and rarely live past the age of 50.43 56-58 Subsequent affected generations have a ...
Robert Paul Lanza, 2004

10 NEWS ITEMS WHICH INCLUDE THE TERM «TELOMERASE»

Find out what the national and international press are talking about and how the term telomerase is used in the context of the following news items.
1
Small Cellular Changes Research May Lead to Cancer Solutions
In 1997, scientists discovered a gene that they believed was the key to cellular immortality. Telomerase Reverse Transcriptase, or TERT, is a catalytic piece of ... «Drug Discovery & Development, Mar 15»
2
Telomere extension turns back aging clock in cultured human cells …
The RNA used in this experiment contained the coding sequence for TERT, the active component of a naturally occurring enzyme called telomerase. «Stanford Medical Center Report, Jan 15»
3
Small Molecule Successfully Targets Telomerase to Destroy Cancer …
Cancer cells are protected from apoptosis by telomerase, which ensures that telomeres do not shorten with every division. Telomerase has therefore been the ... «Genetic Engineering & Biotechnology News, Jan 15»
4
Researchers treat heart attacks with new gene therapy based on …
High magnification image of the heart. Green cells represent cardiomyocytes targeted by the gene therapy. Telomerase reactivation confers cardioprotection ... «Medical Xpress, Dec 14»
5
Geron Corp (GERN) Enters Global Licensing, Collaboration …
... and collaboration agreement with Janssen Biotech, Inc. ("Janssen") to develop and commercialize, imetelstat, Geron's telomerase inhibitor product candidate, ... «StreetInsider.com, Nov 14»
6
Newly-discovered on/off switch could hold the key to healthy aging
Researchers at the Salk Institute have discovered an on/off switch for telomerase, an enzyme that rebuilds a cellular timekeeper known as a telomere. «Gizmag, Sep 14»
7
Sequence of rare kidney cancer reveals unique alterations involving …
Telomerase represent the “clock” of the cell, Creighton said. “This plays a critical role in cell division, and with many cancer cells, telomerase levels are really ... «Baylor College of Medicine News, Aug 14»
8
Unlocking the keys to why we age, the science of immortality and the …
In the 1990s, Dr. Elizabeth Blackburn, Dr. Carol W. Greider and colleagues at the University of California won the Nobel prize for the discovery of telomerase, an ... «National Post, May 14»
9
Atomic level look at telomerase may unlock the secrets to the …
Telomeres and the enzyme telomerase have been in the medical news a lot recently due to their connection with aging and cancer. Telomeres are found at the ... «Nanowerk, May 14»
10
How and Why We Age: The Power of Telomeres and Telomerase
Immortal cells also have telomeres that split into two, but an enzyme called telomerase restores the telomeres to their full size after cell division. For some reason ... «Huffington Post, Jul 13»

REFERENCE
« EDUCALINGO. Telomerase [online]. Available <https://educalingo.com/en/dic-en/telomerase>. May 2024 ».
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