KSIĄŻKI POWIĄZANE ZE SŁOWEM «MACROGLOBULIN»
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1
Wintrobe's Clinical Hematology
c*2-Macroglobulin is a nonspecific proteinase inhibitor that targets a broad
spectrum of protease substrates. It is present in human plasma at concentrations
ranging from 2 to 4 /xmol/L (2 to 3 mg/ml) (Table 20.4). <*2-Macroglobulin can
also be ...
2
Protein Electrophoresis in Clinical Diagnosis
a2-Macroglobulin is one of the two major proteins in the a2-region. Synthesized
mainly by the liver, it is a tetramer composed of four identical subunits. The
subunits are held together as dimers by disulfide bonds. Each a2-macroglobulin
...
3
Biology of Antithrombins
Keinman, R. D., Yuan, A. I., Winder, A. R., and Wang, D., Kinetics of the reaction
of thrombin and a2-macroglobulin, Biochem. J., 231, 417, 1985. 69. Duke Virca,
G. and Travis, J., Kinetics of association of human proteinases with human a ...
4
Clinical Applications of TGF-
I thought it would all be consumed by a2~macroglobulin, nevertheless there is
potent immunosuppression in vivo. How can we explain such findings? LaMarre:
We have been looking at the effect of different modified forms of oQ-
macroglobulin ...
CIBA Foundation Symposium,
2008
5
Acute Phase Proteins Molecular Biology, Biochemistry, and ...
Strickland, D. K., Larsson, L. J., Neuenschwander, D. E., and Bjork, I., Reaction of
proteinases with alpha-2-macroglobulin. Rapid kinetic evidence for a
conformational rearrangement of the initial alpha-2- macroglobulin-trypsin
complex, ...
Andrzej Mackiewicz, Irving Kushner, Heinz Baumann,
1993
6
Hyperthermia In Cancer Treatment: A Primer: A Primer
Immunology 1986; 57(3):367-71. 727. Wollenberg GK, LaMarre J, Rosendal S et
al. Binding of tumor necrosis factor alpha to activated forms of human plasma
alpha 2 macroglobulin. Am J Pathol 1991a; 138(2):265-72. 728. O'Connor-
McCourt ...
Gian F. Baronzio, E. Dieter Hager,
2008
R.F.A. Zwaal, H.C. Hemker. cleavage of a vulnerable region near the middle of
the a2-macroglobulin subunit chain, followed by a conformational change
resulting in steric entrapment of the enzyme [159]. The active site of the bound
protease ...
R.F.A. Zwaal, H.C. Hemker,
1986
8
Neuroinflammatory Mechanisms in Alzheimer's Disease: Basic ...
21 LaMarre J, Wollenberg GK, Gonias SL, Hayes AM (1991) Cytokine binding
and clearance properties of proteinase-activated a2-macroglobulin. Lab Invest
65: 3-14 22 Chu CT, Howard GC, Misra UK, Pizzo SV (1994) a2-Macroglobulin: a
...
Lysiak JJ, Hussaini IM, Gonias SL. alpha 2-Macroglobulin synthesis by the
human monocytic cell line THP-1 is differentiation state-dependent. J Cell
Biochem 1997; 67:492-497. 33. Heumann D, Vischer TL. Immunomodulation by
alpha ...
10
Cell and Molecular Biology of the Testis
The synthesis and secretion of a2-macroglob- ulin by cultured Sertoli cells was
confirmed by immunoprecipitation and radioimmunoassay. To obtain evidence
for the presence of testicular a2-macroglobulin in the adluminal compartment of
the ...
Claude Desjardins, Larry L. Ewing,
1993
WIADOMOŚCI, KTÓRE ZAWIERAJĄ SŁOWO «MACROGLOBULIN»
Sprawdź, o czym dyskutuje się w prasie krajowej i zagranicznej oraz jak jest stosowane słowo
macroglobulin w wiadomościach.
Why Do Dilute Bleach Baths Improve Atopic Dermatitis?
Interestingly, for the first time to our knowledge, α-2 macroglobulin, a ubiquitous protein found in the skin that binds a host of proteases, growth ... «Medical Research News and Interviews on MedicalResearch.com, Lip 15»
Development of a blood-based molecular biomarker test for …
... inflammation (alpha-2 macroglobulin (A2M), beta-2 microglobulin (B2M), carcinoembryonic antigen (CA), haptoglobin, interleukin-1 receptor ... «Nature.com, Lip 15»
Rare gene variant associated with middle ear infections
Another gene called alpha 2-macroglobulin or A2M, which encodes a protein that is found at high levels in very infected ears, is formed in such ... «Baylor College of Medicine News, Cze 15»
Galectin Therapeutics (GALT) Commences GR-MD-02 Phase 2 in …
... on fibrosis as shown by reduced serum alpha-2 macroglobulin, a marker of fibrosis, and reduced liver stiffness as assessed by FibroScan®. «StreetInsider.com, Cze 15»
Cytonics Starts FDA Arthritis Trial, Enrolling First Patient in A2M …
The APIC-CF System concentrates the protease inhibitor Alpha-2-Macroglobulin (A2M) from a patient's own blood for direct injection into a joint ... «Digital Journal, Cze 15»
Thinking Inside The Box: Insights Into One Of The World's Deadliest …
... four of which were metalloproteinases, an alpha-macroglobulin domain containing protein, two peroxiredoxin toxins, two CRISP proteins and ... «Discover Magazine, Cze 15»
Get a celiac test before giving up gluten
We found those who eat the most gluten experience a rise in blood levels of alpha-2 macroglobulin, which indicates inflammation and also is a ... «Toronto Star, Kwi 15»
Prostate cancer New ligand–receptor targets
Using affinity chromatography, Mandelin et al. identified α2-macroglobulin as the receptor for PKRGFQD and GRP78 as the receptor for ... «Nature.com, Mar 15»
Ibrutinib Approved in US for Rare Lymphoma
These abnormal B-cells also overproduce a protein known as immunoglobulin M or IgM (macroglobulin) that may lead to excess bleeding and ... «Medscape, Sty 15»
Final Phase 1 Trial Results Demonstrate Galectin Therapeutics' GR …
The decrease in FibroTest® score was attributable to a marked, statistically significant reduction in serum alpha-2 macroglobulin (A2M), ... «GlobeNewswire, Sty 15»