KSIĄŻKI POWIĄZANE ZE SŁOWEM «UBIQUITINATION»
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1
Ubiquitination and Degradation of Neuronal Nitric Oxide Synthase
Through mutagenesis studies, we were able to localize the ubiquitination site to the calmodulin binding region of nNOS (residues 720-756).
2
The key role of
ubiquitination and sumoylation in signaling ...
K63-linked ubiquitination in kinase activation and cancer Guocan Wang', Yuan
Gao”, Liren Li", Guoxiang Jin”, Zhen Cai”, Jui-I Chao” and Hui-Kuan Linz'3 * '
Department of Cancer Biology, The University of Texas M. D. Anderson Cancer ...
3
Defining the Molecular Mechanism and Functions of PCNA ...
Neutralization of Cdc45 activity by addition of purified Cdc45 antibodies largely
abolished PCNA ubiquitination in the presence of aphidicolin (lane 3). As a
control, preincubation of Cdc45-neutralizing antibodies with recombinant His-
tagged ...
Debbie Jimway Chang,
2009
4
Casein Kinase I, Axin and GSK3-beta Regulate Smad3 ...
6 Conclusions and Future Directions 6.1 Smad3 Ubiquitination Negatively
Regulates TGF-fi Signaling. The theme of this entire thesis is negative
regulations of the TGF-(3 pathway through Smad3 ubiquitination and
degradation. As is true to ...
5
The Role of RIP
Ubiquitination in the TNFalpha Signaling Pathway
... NF-κB activation. In this study, we have investigated the role of RIP
ubiquitination by mapping its ubiquitination site. Our results indicate that K377 in
the intermediate domain of RIP is the functional ubiquitination site, since
expression of the ...
6
Regulation of Estrogen Receptor-alpha
Ubiquitination and ...
ABSTRACT Nicholas Brandon Berry Regulation of Estrogen Receptor-alpha (
ERα) Ubiquitination and Proteasome- mediated Receptor Degradation Breast
cancer is the most common cancer among women, and the majority (~70%)
express ...
Nicholas Brandon Berry,
2008
7
Role of
Ubiquitination in Caenorhabditis Elegans Development ...
2.4.5 In vivo defects in ubiquitination and embryogenesis The uba-1 gene
encodes the only known E1 ubiquitin-activating enzyme in C. elegans, so a
defect in its activity is predicted to impair subsequent steps in the enzymatic
cascade and ...
10.5 HISTONE UBIQUITINATION AND TRANSCRIPTION REGULATION H2A
and H2B are targets for ubiquitination which brings opposite effects on
transcription. In humans H2A K119 ubiquitination is mediated by Bmi-1 and
RING1/2, core ...
9
The Cell Cycle: Principles of Control
Protein Degradation in Cell-Cycle Control 3-9 SCF catalyzes ubiquitination of
phosphorylated substrates using interchangeable substrate-targeting subunits
SCF and the APC are members of a family of ubiquitin-protein ligases whose
active ...
10
Ubiquitin and Protein Degradation
Ubiquitination and degradation of IkB plays an essential role in NF-kB activation.
Here we describe an in vitro IkBo ubiquitination assay system in which purified El
, E2, sCF',Trcpl E3, IkBq, IKK2, and Ub were used to generate ubiquiti- nated ...
Raymond J. Deshaies,
2005
WIADOMOŚCI, KTÓRE ZAWIERAJĄ SŁOWO «UBIQUITINATION»
Sprawdź, o czym dyskutuje się w prasie krajowej i zagranicznej oraz jak jest stosowane słowo
ubiquitination w wiadomościach.
OTUB1 inhibits the ubiquitination and degradation of FOXM1 in …
Ubiquitination is a posttranslational modification that confers a range of protein regulatory functions, including targeting a substrate protein for degradation, ... «Nature.com, Lip 15»
Enhanced T-cell activation and differentiation in lymphocytes from …
The requirement for LAT ubiquitination in mediating TCR-induced T-cell proliferation was also examined. Purified CD4+ and CD8+ T cells from TG−, WT and ... «Nature.com, Cze 15»
Opening access to genes and environment research
These changes may involve modification of DNA bases and histones, such as methylation, ubiquitination or acetylation. A recently published systematic review ... «BMC Blogs Network, Cze 15»
Acute kidney injury Activated protein C protective in IRI
To investigate the mechanism by which aPC regulates YB-1 expression, the researchers examined ubiquitination. They found that aPC stabilized expression of ... «Nature.com, Cze 15»
UCSF Journal Club
IMMUNOLOGY: The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis. Onizawa, M., et al. (Ma, A.). «Synapse, Maj 15»
Researchers discover new mechanism controlling cell response to …
Moffitt researchers found that SIRT1 is modified by a process called ubiquitination, in which a small residue called ubiquitin is added to SIRT1. This modification ... «Phys.Org, Kwi 15»
Epigenetic Role for Ubiquitin Receptors
Due to its name, it's not difficult to think of the ubiquitination pathway as having a role in almost all cellular processes. However, until recently the evidence ... «Genetic Engineering & Biotechnology News, Kwi 15»
Breakthrough In Cancer Research
The ubiquitin system tags these proteins and sends them for destruction in the ... When ubiquitination is mediated by another component of the system (and ... «PR Newswire, Kwi 15»
Turned on by cleavage; turned off by methylation and ubiquitination
Notch signaling regulates several processes during development, and aberrant signaling contributes to human disease. The Notch receptor is proteolytically ... «Science Magazine, Mar 15»
The Link Between Ubiquitination & Receptor Stability
Modifying the stability of the AMPA receptor through ubiquitination could lead to new treatments for diseases such as Alzheimer's. Asian Scientist Newsroom ... «Asian Scientist Magazine, Lut 15»