O QUE SIGNIFICA RIBAVIRIN EM INGLÊS
Ribavirina
A ribavirina é um análogo de guanosina usado para parar a síntese de RNA viral e a coleta de ARNm viral, portanto, é um inibidor de nucleósido. As suas marcas incluem Copegus, Rebetol, Ribasphere, Vilona e Virazole, e é um medicamento anti-viral usado fora do rótulo para infecção severa por RSV, infecção por hepatite C e outras infecções virais. A ribavirina é um pró-fármaco, que quando metabolizado se assemelha a nucleótidos de ARN de purina. Nesta forma, interfere com o metabolismo do ARN necessário para a replicação viral. A forma como isso afeta exatamente a replicação viral é desconhecida; Muitos mecanismos foram propostos para isso, mas nenhum deles foi comprovado até o momento. Múltiplos mecanismos podem ser responsáveis por suas ações. É na Lista de Medicamentos Essenciais da Organização Mundial de Saúde, uma lista da medicação mais importante necessária em um sistema básico de saúde.
definição de ribavirin no dicionário inglês
A definição de ribavirina no dicionário é um tipo de medicamento antiviral usado contra muitos vírus como a gripe e, em combinação com outros medicamentos, a hepatite C.
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10 LIVROS EM INGLÊS RELACIONADOS COM «RIBAVIRIN»
Descubra o uso de
ribavirin na seguinte seleção bibliográfica. Livros relacionados com
ribavirin e pequenos extratos deles para contextualizar o seu uso na literatura.
1
Dr. Melissa Palmer's Guide to Hepatitis & Liver Disease
But not everyone experiences adverse side effects, and some people experience
no side effects at all. Newer improved drugs with a similar structure to ribavirin (
known as ribavi- rin analogues) but less side effects are in the process of being ...
TABLE 19-5. Factors Predictive of Viral Response to Interferon-Based Therapy
for Hepatitis C Virus FACTOR ASSOCIATION WITH VIRAL RESPONSE
Genotypes 2 and 3 significantly more responsive to peginterferon alfa plus
ribavirin than ...
3
Handbook of Modern Hospital Safety, Second Edition
Methods Site Visit #1 (July 17 and 18, 1990) Twenty milligrams per mililiter is the
recommended concentration of ribavirin prepared as the starting solution for the
drug reservoir of the Viratek small particle aerosol generator (SPAG) model ...
4
Biological, Chemical, and Radiological Terrorism: Emergency ...
Ribavirin, a nonimmunosuppressive nucleoside analogue, is effective for some of
the VHF viruses. High-risk Lassa fever patients treated with ribavirin have
decreased mortality, and ribavirin may reduce morbidity in all Lassa fever
patients.
5
The Guide to Off-label Prescription Drugs: New Uses for ...
In general,treatment with interferon-based drug regimens has shown limited
success in the treatment of hepatitis C.Combinations of pegylated interferons and
ribavirin (an antiviral drug) are now the preferred treatments for most patients with
...
Kevin R. Loughlin, Joyce A. Generali,
2006
One study conducted at FHCRC treated 25 HCT recipients with upper tract RSV
disease with low-dose aerosolized ribavirin administered at a high concentration
(60mg/mL) for 2 h each day (total: 2 g/day) (11). Unfortunately, 8 out of these 25 ...
Raleigh A. Bowden, Per Ljungman, David R. Snydman,
2010
7
Schiff's Diseases of the Liver
Ribavirin is a guanosine nucleoside analog approved initially for the treatment of
respiratory syncytial virus in neonates [552]. Several postulated mechanisms of
action of ribavirin for the treatment of hepatitis C have been proposed since its ...
Eugene R. Schiff, Willis C. Maddrey, Michael F. Sorrell,
2011
8
Curbside Consultation of the Liver: 49 Clinical Questions
The management of patients who develop anemia during treatment with peginter
- feron and ribavirin is an inexact science and remains controversial. This is
because it has been very difficult to interpret the retrospective analyses
performed on ...
Mitchell L. Shiffman,
2008
9
Primary Care Medicine: Office Evaluation and Management of ...
ribavirin doses of 1,000-1,200 mg daily are required. Sustained response rates of
42% to 51% have been reported. For patients with hepatitis C genotypes 2 and 3,
24 weeks of combination therapy suffice to achieve sustained response rates ...
Allan H. Goroll, Albert G. Mulley,
2009
10
Infectious Diseases in Immunocompromised Hosts
:3-26-38 5.1.3 EVOLUTION OF THERAPIES AND TREATMENT OF
RESPIRATORY SYNCYTIAL VIRUS INFECTIONS The use of aerosolized
ribavirin in the treatment of RSV-induced infections, particulary in severe disease,
has been well ...
Vassil St. Georgiev,
1997
10 NOTÍCIAS NAS QUAIS SE INCLUI O TERMO «RIBAVIRIN»
Conheça de que se fala nos meios de comunicação nacionais e internacionais e como se utiliza o termo
ribavirin no contexto das seguintes notícias.
AbbVie (ABBV) Announces FDA Approval of TECHNIVIE in …
"The approval of TECHNIVIE in combination with ribavirin is important for these patients who now have an approved all-oral, interferon-free treatment option that ... «StreetInsider.com, jul 15»
Sofosbuvir plus pegylated interferon/ribavirin is highly effective for …
A throwback regimen of sofosbuvir (Sovaldi), ribavirin and pegylated interferon taken for 12 weeks cured 93% of people with hepatitis C virus (HCV) genotype 3 ... «aidsmap, abr 15»
Merck's Grazoprevir/Elbasvir Posts High Hep C Cure Rates
Merck's fixed-dose combination tablet, grazoprevir/elbasvir, given with or without ribavirin, cured over 90 percent of various subgroups of people with hepatitis C ... «AIDSmeds.com HIV/AIDS Treatment News, abr 15»
Newer HCV Agents Mostly Cost-Effective
The question has been how the new agents compare, both in cost and efficacy, with earlier treatments using a protease inhibitor, peg-interferon, and ribavirin. «MedPage Today, mar 15»
NICE recommends simeprevir (Olysio) in combination with …
The draft guidance recommends simeprevir, in combination with peginterferon alfa and ribavirin, as an option for treating both genotypes 1 and 4 chronic ... «NICE, jan 15»
Valeant Pharmaceuticals North America LLC Issues Voluntary …
... North America LLC (VPNA) is issuing a voluntary recall of one lot of Virazole® (ribavirin powder for solution), 100 mL, 6g Vial, 4-pack to the user level. «PR Newswire, dez 14»
AbbVie 3D regimen and sofosbuvir/ribavirin show high cure rates for …
AbbVie's 3D regimen (paritaprevir/ombitasvir/ritonavir plus dasabuvir) with ribavirin for 12 weeks and Gilead Science's sofosbuvir (Sovaldi) plus ribavirin for 24 ... «aidsmap, nov 14»
New Agents Show Promise in Cirrhosis
And adding a third drug -- the relatively inexpensive, nonspecific antiviral ribavirin -- allowed investigators to get similar outcomes with just 12 weeks of therapy, ... «MedPage Today, nov 14»
Enanta Pharmaceuticals Announces Data Presentations on …
TURQUOISE-II: Regimens of ABT-450/r/Ombitasvir and Dasabuvir With Ribavirin Achieve High SVR12 Rates in HCV Genotype 1-Infected Patients with ... «Business Wire, out 14»
Achillion Pharma (ACHN) Issues Encouraging Update from ACH …
... proxy study evaluating ACH-3102, Achillion's second-generation NS5A inhibitor, in combination with sofosbuvir, without ribavirin, for eight weeks of treatment ... «StreetInsider.com, ago 14»