CE ÎNSEAMNĂ CISPLATIN ÎN ENGLEZĂ?
cisplatina
Cisplatin, cisplatinum sau cis-diamminedichloroplatinum este un medicament chimioterapic. A fost primul membru al unei clase de medicamente antineoplazice care conțin platină, care acum include și carboplatina și oxaliplatina. Aceste complexe de platină reacționează in vivo, legând și provocând reticularea ADN-ului, ceea ce declanșează în cele din urmă apoptoza.
Definiția cisplatin în dicționarul Engleză
Definiția cisplatinei din dicționar este un medicament citotoxic care acționează prin împiedicarea replicării ADN-ului și, prin urmare, a diviziunii celulare, utilizată în tratamentul tumorilor, în special a ovarelor și a testiculelor.
CĂRȚI ÎN ENGLEZĂ ÎN LEGĂTURĂ CU «CISPLATIN»
Descoperă întrebuințarea
cisplatin în următoarea selecție bibliografică. Cărți în legătură cu
cisplatin și extrase din aceasta pentru a furniza contextul de întrebuințare al acestuia în literatura Engleză.
1
Cisplatin: chemistry and biochemistry of a leading ...
This volume provides all scientists, from coordination chemists to oncologists, with a unique resource detailing the state-of-the-art and future research perspectives, together with the fascinating story, of cisplatin.
endolymphatic ionic concentrations are not altered, nor is strial sodium,
potassium adenosine triphosphatase (Na+, K+-ATPase) activity decreased.88
Other Manifestations of Cisplatin Ototoxicity Tinnitus as a sequela to cisplatin
therapy ...
Peter S. Roland, John A. Rutka,
2004
3
Principles of Chemistry: The Molecular Science
K2PtCl4(s) 2 NH3(aq) 9: Pt(NH3)2Cl2(s) 2 KCl(aq) potassium
tetrachloroplatinate ammonia cisplatin If the reaction starts with 5.00 g ammonia
and 50.0 g ktcp, (a) which is the limiting reactant? (b) How many grams of
cisplatin are produced?
John Moore, Conrad Stanitski, Peter Jurs,
2009
4
Principles and Practice of Gynecologic Oncology
Intraperitoneal (IP) cisplatin was administered in the following method in a Phase
III intergroup study (INT 0051) of IP cisplatin/IV cyclophosphamide versus IV
cisplatin/lV cyclophosphamide (2). A totally implantable device (intravenous port)
...
3 Cisplatin Cisplatin, cis-diamminedichloroplatinum(II), a square planar Pt2þ
complex (Figure 3.1), was the first metalbased agent to enter into worldwide
clinical use for the treatment of cancer. Currently, cisplatin is used either by itself
or in ...
6
Cancer Drug Resistance Research Perspectives
However, the current regimens of cisplatin-based chemotherapy have no
advantages for survival due to less sensitivity, or intrinsic, or acquired
chemoresistance. Despite the widespread study in this field, the exact
mechanisms of cisplatin ...
Reduced Drug Uptake Although a few studies have demonstrated a lack of
change in cisplatin uptake in cisplatin-resistant cells (15), these appear to be
isolated incidences. In fact, reduced drug uptake is prevalent and surfaces early
in the ...
8
Principles of Pharmacology: The Pathophysiologic Basis of ...
А5 with the alkylating agents, the anticancer properties of cisplatin were
discovered by a chance observation. While studying the effects of electricity on
bacteria, it was found that a product of the platinum electrode was inhibiting DNA
synthesis ...
David E. Golan, Armen H. Tashjian, Ehrin J. Armstrong,
2011
9
Involvement of P70S6K in
Cisplatin-induced Cell Death
Figure 2 shows that a 48 h exposure to cisplatin caused a concentration-
dependent increase in PARP cleavage in H69 cells such that the cleaved
fragment of PARP appeared when cells were treated with 20 uM cisplatin and
increased further ...
10
Biomechanics and Biomaterials in Orthopedics
Cisplatin is one of the antimitotics which would be suitable for mixing with cement
and it has the following characteristics: it is often used to treat primary bone
tumors; in the context of bone metastases from visceral tumors, it is generally
used in ...
Dominique G. Poitout,
2004
ȘTIRI NOI CARE INCLUD TERMENUL «CISPLATIN»
Află ce ziare naționale și internaționale au scris despre și cum este întrebuințat termenul
cisplatin în contextul următoarelor știri.
Cancer drug 49 times more potent than Cisplatin
Tests have shown that a new cancer drug, FY26, is 49 times more potent than the clinically used treatment Cisplatin. «Medical Xpress, Iul 15»
FDA asks panel to weigh benefit, risk of Lilly lung cancer drug
In a 1,093-patient clinical trial patients who received necitumumab together with the chemotherapy drugs gemcitabine and cisplatin survived an ... «Business Insider, Iul 15»
Concurrent Chemoradiotherapy Should Remain Standard of Care …
Researchers sought to assess the efficacy of consolidation chemotherapy with docetaxel plus cisplatin after concurrent chemoradiotherapy with ... «Cancer Therapy Advisor, Iul 15»
Mary Tankersley's Declaration of Independence: Childhood Cancer …
... hospital receiving a chemotherapy cocktail containing methotrexate, cisplatin and doxorubicin; drugs that are all part of our outdated arsenal. «Huffington Post, Iul 15»
5 Big Upcoming FDA Decisions Expected in July
... the Biologics License Application (BLA) filing of necitumumab injection in combination with gemcitabine and cisplatin for first-line treatment of ... «24/7 Wall St., Iul 15»
Ad Comm approaches for Lilly's necitumumab BLA (LLY)
... Eli Lilly's (LLY +1%) Biologics License Application (BLA) seeking approval for necitumumab, in combination with gemcitabine and cisplatin, ... «Seeking Alpha, Iul 15»
Few Approved Targeted Therapies for GE Cancers
Additive antitumor effects have been seen when trastuzumab was combined with capecitabine or fluorouracil (FU) plus cisplatin, she said. «Clinical Oncology News, Iul 15»
Eli Lilly preps a familiar case for FDA review of a marginal cancer drug
"Overall," Lilly noted in its review, "we found that the safety profile of necitumumab plus gemcitabine and cisplatin was acceptable and in line ... «FierceBiotech, Iul 15»
BIRC5/Survivin as a target for glycolysis inhibition in high-stage …
Paclitaxel, cisplatin and lonidamine in advanced ovarian cancer. A phase II study. Eur J Cancer 2001; 37: 364–368. | Article | PubMed | CAS ... «Nature.com, Iul 15»
OTUB1 inhibits the ubiquitination and degradation of FOXM1 in …
FOXM1 confers acquired cisplatin resistance in breast cancer cells. Mol Cancer Res 2010; 8: 24–34. | Article | PubMed | ISI | CAS |; McGovern ... «Nature.com, Iul 15»