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在"英语"词典里phenformin}的意思

词典
词典
section

单词 PHENFORMIN的词源

From phen(yl) + form(aldehyde) +-in.
info
语源学是对单词起源和它们的结构和意义变化的研究
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英语中PHENFORMIN的发音

phenformin  [fɛnˈfɔːmɪn] play
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PHENFORMIN的语法类别

noun
形容词
动词
副词
代词
介词
连词
限定词
感叹词

PHENFORMIN在英语中的意思是什么?

点击查看«phenformin»在英语词典里的原始定义
点击查看在中文词典里此定义的自动翻译

苯乙双胍

Phenformin

苯乙双胍是双胍类的抗糖尿病药物。 它由Ciba-Geigy作为DBI上市,但是由于乳酸性酸中毒的风险很高,在20世纪70年代末期被淘汰,在50%的病例中是致命的。 苯乙双胍于1957年被Ungar,Freedman和Seymour Shapiro发现,为美国维生素公司工作。 1958年开始的临床试验表明其有效,但具有胃肠道副作用。 Phenformin is an antidiabetic drug from the biguanide class. It was marketed as DBI by Ciba-Geigy, but was withdrawn from most markets in the late 1970s due to a high risk of lactic acidosis, which was fatal in 50% of cases. Phenformin was discovered in 1957 by Ungar, Freedman and Seymour Shapiro, working for the US Vitamin Corporation. Clinical trials begun in 1958 showed it to be effective, but with gastrointestinal side effects.

在英语 词典里phenformin的定义

词典中苯乙双胍的定义是在糖尿病治疗中口服给药的双胍以降低血糖浓度; 它在很大程度上被二甲双胍取代。 分子式:C10H15N5。

The definition of phenformin in the dictionary is a biguanide administered orally in the treatment of diabetes to lower blood concentrations of glucose; it has been largely superseded by metformin. Formula: C10H15N5.

点击查看«phenformin»在英语词典里的原始定义
点击查看在中文词典里此定义的自动翻译

PHENFORMIN押韵的英语 单词


adermin
əˈdɜːmɪn
Brahmin
ˈbrɑːmɪn
determine
dɪˈtɜːmɪn
dormin
ˈdɔːmɪn
Emin
ˈiːmɪn
enlumine
ɛnˈljuːmɪn
ermine
ˈɜːmɪn
extermine
ɪkˈstɜːmɪn
haemin
ˈhiːmɪn
hemin
ˈhiːmɪn
illumine
ɪˈluːmɪn
legumin
lɪˈɡjuːmɪn
lumen
ˈluːmɪn
lumine
ˈluːmɪn
metformin
metˈfɔːmɪn
predetermine
ˌpriːdɪˈtɜːmɪn
redetermine
ˌriːdɪˈtɜːmɪn
reillumine
ˌriːɪˈluːmɪn
toxalbumin
ˌtɒksælˈbjuːmɪn
vermin
ˈvɜːmɪn

PHENFORMIN一样开头的英语单词

phenarsazine chloride
phenate
phenazine
phencyclidine
phene
phenetic
pheneticist
phenetics
phenetidine
phenetole
phengite
phengophobia
phenic
phenix
phenmetrazine
phenobarbital
phenobarbitone
phenocopies
phenocopy
phenocryst

PHENFORMIN一样开头的英语单词

admin
albumin
Amin
benjamin
cobalamin
cosmin
cumin
gamin
Jiang Zemin
maximin
min
multivitamin
provitamin
ramin
saimin
serum albumin
sysadmin
theremin
thiamin
vitamin

英语近义词词典里phenformin的近义词和反义词

近义词

«phenformin»的25种语言翻译

翻译者
online translator

PHENFORMIN的翻译

通过我们的英语多语言翻译器,找到phenformin25种语言翻译
该章节所呈现的将phenformin由 英语向其他语言的翻译是通过自动统计翻译获得的;在英语中基本的翻译单位是单词«phenformin»。

翻译者英语 - 中文

苯乙双胍
1,325 数百万发言者

翻译者英语 - 西班牙语

fenformina
570 数百万发言者

英语

phenformin
510 数百万发言者

翻译者英语 - 印地语

phenformin
380 数百万发言者
ar

翻译者英语 - 阿拉伯语

فينفورمين
280 数百万发言者

翻译者英语 - 俄语

фенформин
278 数百万发言者

翻译者英语 - 葡萄牙语

fenformina
270 数百万发言者

翻译者英语 - 孟加拉语

phenformin
260 数百万发言者

翻译者英语 - 法语

phenformin
220 数百万发言者

翻译者英语 - 马来语

Phenformin
190 数百万发言者

翻译者英语 - 德语

Phenformin
180 数百万发言者

翻译者英语 - 日语

フェンホルミン
130 数百万发言者

翻译者英语 - 韩语

펜 포르 민
85 数百万发言者

翻译者英语 - 印尼爪哇语

Phenformin
85 数百万发言者
vi

翻译者英语 - 越南语

phenformin
80 数百万发言者

翻译者英语 - 泰米尔语

phenformin
75 数百万发言者

翻译者英语 - 马拉地语

Phenformin
75 数百万发言者

翻译者英语 - 土耳其语

fenforminin
70 数百万发言者

翻译者英语 - 意大利语

fenformina
65 数百万发言者

翻译者英语 - 波兰语

fenformina
50 数百万发言者

翻译者英语 - 乌克兰语

фенформин
40 数百万发言者

翻译者英语 - 罗马尼亚语

phenformin
30 数百万发言者
el

翻译者英语 - 希腊语

phenformin
15 数百万发言者
af

翻译者英语 - 布尔语(南非荷兰语)

phenformin
14 数百万发言者
sv

翻译者英语 - 瑞典语

fenformin
10 数百万发言者
no

翻译者英语 - 挪威语

phenformin
5 数百万发言者

phenformin的使用趋势

趋势

词语 «PHENFORMIN»的使用趋势

0
100%
频率
很少使用
33
/100
此处所显示的地图给出了词语«phenformin»在不同国家的使用频率。
phenformin的主要搜索趋势和常见用法
用户为查找我们的英语在线词典以及单词«phenformin»的最常用表达而进行的主要搜索的列表。

词语«PHENFORMIN» 随时间而变化的使用频率

该图表展现了单词«phenformin»在过去500年中的用法频率的每年演化其实施是基于分析词语«phenformin»从1500年到现在在 英语数字出版物中出现的频率。

phenformin的英语文献、引用和新闻中的使用范例

示例

«PHENFORMIN»相关的英语书籍

在以下的参考文献中发现phenformin的用法。与phenformin相关的书籍以及同一来源的简短摘要提供其在 英语文献中的使用情境。
1
Endocrine Pharmacology: Physiological Basis and Therapeutic ...
Such a process is consistent with the occurrence of lactic acidosis, which in certain clinical circumstances may occur when phenformin is being used. c. It has also been suggested that these drugs produce a decline in gluconeogenesis from ...
P. J. Bentley, 1980
2
The Dictionary of Substances and Their Effects: O-S
phenformin. O". NH. NH. II. II. CH2CH2—. NH—. C—. NH—. C—. NH2. C10H15N5 Mol. Wt. 205.26 CAS Registry No. 114-86-3 Synonyms N-(2- phenylethyl)imidodicarbonimidic diamide; 1-phenethylbiguanide; Azucaps; fenformin; Glyphen; ...
S. Gangolli, Royal Society of Chemistry (Great Britain), 1999
3
Lewis' Dictionary of Toxicology
Upon decomposition by heating, it emits very toxic fumes (Cl" and NOX). phenestrin. fenesterine. phenethyl diguanide. phenformin. phenethylamine 03- phenethylamine; benzene- ethanamine; 0-phenylethylamine; 2- phenylethylamine; ...
Robert Alan Lewis, 1998
4
Frontiers in Neurodegenerative Disorders and Aging: ...
Vinnitski and lakumenko [135] have shown that treatment with phenformin increased the immunological reactivity and inhibited carcinogenesis induced by s.c. administration of 20- methylcholanthrene in BALB/c mice. 1n high fat-fed hamsters, ...
Tomris Özben, Mordechai Chevion, 2004
5
Clinical Drug Trials and Tribulations, Revised and Expanded, ...
Shortly afterwards, the labeling of phenformin was again changed in indicated that the drug should be considered only as a last resort when other oral agents were ineffective and insulin could not be used. This labeling change was a ...
Allen Cato, Lynda Sutton, Allen Cato III, 2002
6
Insulin Resistance and Cancer: Epidemiology, Cellular and ...
This notion is especially appealing since AMPK activators, such as metformin/ phenformin and TZDs, are already widely used for type 2 diabetes treatment and additional novel AMPK activators are being actively developed [15]. Indeed, in ...
I. George Fantus, 2011
7
ClinicalTrials: Design, Conduct and Analysis
The patient should be informed of the potential risks and This study providedno evidence that phenformin was more efficacious than diet alone or than diet and insulin in prolonging life for the patients studied. In fact, the observed mortality from ...
Curtis L. Meinert, 2012
8
Clinical Diabetes Mellitus: A Problem-oriented Approach
That phenformin was also associated with excess cardiovascular mortality in the UGDP study3 was hardly noticed; in fact, in this study, phenformin was also found to be associated with an increase in blood pressure, an observation that was ...
John K. Davidson, 2000
9
Consolidated List of Products Whose Consumption And/or Sale ...
BRA 14 Dec 1977 Combination products containing phenformin are prohibited. ( Reference: (BRAPT) Portaria do Servico Publico Federal, No.30, , Dec 1977) DNK 1978 Withdrawn following reports of occasional but sometimes fatal cases of ...
United Nations, 1983
10
PROGRESS IN MEDICINAL CHEMISTRY
Phenformin (/3-phenethylbiguanide, Dibotin) forms metal complexes with Cu and Ni, but not with Zn, Cd, Mg and the alkali earthsuzb. Assuming that chlorhexidine itself does not form a complex with Mg, then the observations that Mg++ ...
Gwynn Pennant Ellis, Geoffrey Buckle West, 2011

包含词语«PHENFORMIN»的新条目

找出国内和国际出版社所讨论的内容,以及词语phenformin在以下新条目的上下文中是如何使用的。
1
Discover China metformin market analysis and 2019 forecasts
However, influenced by the side effects of phenformin, metformin was once suggested to exit the market. Under the persistent exploration of ... «WhaTech, 七月 15»
2
Metformin induces ER stress-dependent apoptosis through miR-708 …
... Gonzalez-Herrera KN, Asara JM, Haigis MC, Struhl K. Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates ... «Nature.com, 六月 15»
3
Landmarks in Diabetes: 1995 to 2015
... while the US Food and Drug Administration (FDA) focused on removing a related but more toxic compound, phenformin, from the market. «Medscape, 五月 15»
4
What's more scary? Diabetes drugs, not disease, says doctor
There was a more dangerous form of the drug called phenformin. But following widespread report of complications, it was withdrawn. CVK ... «Times of India, 四月 15»
5
Nano packages for anti-cancer drug delivery
Phenformin-loaded nanoparticles kill both cancer cells and cancer stem cells, leading to tumor regression. Credit: A*STAR Institute of ... «Phys.Org, 三月 15»
6
Niewydolność serca a cukrzyca
BMJ, 2007; 335: 497 43. Misbin R.I.: Phenformin-associated lactic acidosis: pathogenesis and treatment. Ann. Intern. Med., 1977; 87: 591–595 «Medycyna Praktyczna, 一月 15»
7
Metformin Label Too Restrictive on Renal Grounds, Limits Use
The rationale behind the current FDA label for metformin was established in 1994, when there was strong evidence that phenformin, another ... «Medscape, 一月 15»
8
Outdated Warning on Antidiabetic Drug Curtails Its Use
The agency based its safety recommendations on the experience of phenformin, a similar drug that was implicated in fatal cases of lactic ... «Cornell Chronicle, 一月 15»
9
Regulated vs unregulated
This is why the public will hear of some drugs, for example Vioxx, Propulsid, Fen-Phen, Phenformin, and Melleril, that were withdrawn from the ... «Jamaica Observer, 九月 14»
10
The Vicious Cycle of Dangerous Diabetes Drugs
Two drugs in this class, Phenformin and Buformin, have been withdrawn from the market due to their tendency to cause lactic acidosis – a ... «Injury Lawyer News, 一月 14»

参考文献
« EDUCALINGO. Phenformin [在线]. 可用 <https://educalingo.com/zh/dic-en/phenformin>. 五月 2024 ».
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