与 «VALPROIC ACID»相关的英语书籍
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valproic acid的用法。与
valproic acid相关的书籍以及同一来源的简短摘要提供其在 英语文献中的使用情境。
Although valproic acid increased the concentrations of lamotrigine, the age effect
was less evident. In any age group, the dose-normalized lamotrigine
concentrations were approximately fivefold higher in patients comedicated with
valproic ...
2
Walker's Pediatric Gastrointestinal Disease
09 Valproic acid is related structurally to two known hepatotox- ins: hypoglycin,
which causes Jamaican vomiting sickness, characterized by microvesicular
steatosis, and 4-pentenoic acid, which causes microvesicular steatosis in rat liver
and ...
Ronald (Professor of Paediatrics Kleinman, 2008
3
Drug Interactions in Infectious Diseases
The co-administration of carbapenems and valproic acid may lead to decreased
concentrations of valproic acid [239]. The proposed mechanism is that
carbapenems may interfere with the hydrolysis of valproic acid's glucuronide
metabolite to ...
Stephen C. Piscitelli, Keith A. Rodvold, Manjunath P. Pai, 2011
4
Drugs in Pregnancy and Lactation: A Reference Guide to Fetal ...
Valproic acid and its salt form, sodium valproate, are anticonvulsants used in the
treatment of seizure disorders. The drugs readily cross the placenta to the fetus.
At term, the range of cord blood:maternal serum ratios of total valproic acid ...
Gerald G. Briggs, Roger K. Freeman, Sumner J. Yaffe, 2011
5
Lexicon of Psychiatry, Neurology, and the Neurosciences
valproic acid + ethosuximide valproic acid/panic disorder decrease in DMI
plasma levels. Discontinuation of VPA was followed by an increase in DMI
plasma levels that may have been caused by greater DMI binding or by
discontinuation of ...
Structures of valproic acid analogues and selected metabolites. valproic acid in a
1:1 molar ratio, the chemical form being described as sodium hydrogen-bis-(2-
propylpentanoate). The free acid (pKa = 4.56-4.8) [9] and sodium salt forms are ...
7
Side Effects of Drugs Annual: A worldwide yearly survey of ...
valproate. Reports that carbapenems markedly reduce serum concentrations of
valproic acid continue to appear [231–235A]. All carbapenems have been
implicated, although in one unusual case valproic acid concentrations were
reduced by ...
8
Tryptophan: Biochemical and Health Implications
At high doses, metyrapone (20 mg per 100 g body weight) appeared to inhibit
tryptophan-induced stimulation of hepatic protein synthesis. 6.6.3.4 Valproic Acid
Valproic acid, a branched-chain fatty acid, which has been used in the treatment
of ...
9
The Treatment of Epilepsy
Valproic acid glucuronide and 3-oxo-valproic acid are by far the most abundant
metabolites, representing about 40% and 33%, respectively, of the urinary
excretion of a valproic acid dose [11]. Anticonvulsant activity that is similar in
potency to ...
Simon D. Shorvon, Emilio Perucca, Jerome Engel, Jr., 2009
10
PNDR, Psychologists' Neuropsychotropic Drug Reference
cardiovascular malformations and anomalies involving various other body
systems, cranial defects, and spina bifida, The incidence of neural tube defects
among neonates born to women who received valproic acid pharmacotherapy
during ...
Louis A. Pagliaro, Ann M. Pagliaro, 1999
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Search for common targets of lithium and valproic acid identifies …
Valproic acid (VPA) is a histone deacetylase inhibitor, and lithium (Li) may have downstream epigenetic actions. To identify genes commonly affected by both ... «Nature.com, 七月 15»
Antipsychotics May Be Deadlier Than Thought for Dementia Patients
The investigators also looked at other psychiatric drugs and found the risk of death associated with the mood stabilizer valproic acid (Depakene) was similar to ... «U.S. News & World Report, 三月 15»
Enriched environment staves off autism-like behavior in rats
Rats exposed in utero to the epilepsy drug valproic acid (VPA), a risk factor for autism, do not develop autism-like behaviors if they are reared in a stimulating ... «SFARI News, 十一月 14»
Carbapenems and Valproic Acid: Risky Combination?
Valproic acid (VPA) is a common first-line antiepileptic medication used in a variety of patient populations, with a therapeutic target concentration of 50-100 ... «Medscape, 六月 14»
Old standby valproic acid appears effective against hyperactive …
NEW YORK – Valproic acid might be effective for treating hyperactive delirium, results ... Valproic acid is the most widely used agent for the treatment of seizures ... «Clinical Psychiatry News Digital Network, 五月 14»
Mood-Stabilizing Rx Tied to Lower Risk of Some Cancers
Valproic acid is a type of medication called a "mood-stabilizer" that is used to treat a number of conditions, including some types of seizures, mania in patients ... «dailyRx, 三月 14»
Mood Drug May Prevent Some Cancer, Study Finds
The drug, called valproic acid, is already being tested as a possible treatment for several cancers. But a new study shows that veterans who were taking the drug ... «NBCNews.com, 三月 14»
Valproic acid metabolism and obesity: an interview with Dr …
Valproic acid is one of the most widely prescribed drugs for the treatment of epilepsy. It has also been shown to be effective for the treatment of mood disorders ... «News-Medical.net, 二月 14»
Valproic acid may treat obesity
Scientists have discovered a potential new use for the epilepsy drug valproic acid. The drug activates a particular protein that is a known drug target in treating ... «Epilepsy Action, 二月 14»
Epilepsy drug could help cure fatty liver disease
Researchers have discovered that valproic acid - a widely prescribed drug for treating epilepsy ? is capable of reducing fat accumulation in the liver and ... «Daily News & Analysis, 一月 14»
